Protein Alignment Ythdf and ECT2

DIOPT Version :10

• Sequence 1: NP_651322.1
• Gene: Ythdf / 42995
• FlyBaseID: FBgn0039261
• Length: 700
• Species: Drosophila melanogaster
• Sequence 2: NP_187955.2
• Gene: ECT2 / 820548
• AraportID: AT3G13460
• Length: 667
• Species: Arabidopsis thaliana
• Alignment Length: 637
• Identity: 169/637 - (26%)
• Similarity: 261/637 - (40%)
• Gaps: 133/637 - (20%)

  Fly    31 ASYENLSSPTHDEVSGNDNSMQFQYP-------------PFNFKENCN--------TPWNNMNKG 74
            |.|:......|.:|...|.|:....|             |:|..:..|        |.:......
plant    37 AVYQYGGVDVHGQVPSYDRSLTPMLPSDAADPSVCYVPNPYNPYQYYNVYGSGQEWTDYPAYTNP 101

  Fly    75 RKANANHDSYRRHGHSI-PNNTRRDEHQVNPWNSRKP---------AAQSFRNENDQPSTKLDNR 129
            ...:.|...|..:|..: |.......:..:|..|..|         .||.::..|..|::. ...
plant   102 EGVDMNSGIYGENGTVVYPQGYGYAAYPYSPATSPAPQLGGEGQLYGAQQYQYPNYFPNSG-PYA 165

  Fly   130 TSDEAQNQEVVAAPKKTTWASIASQPAKLTSRAASTTSNSKKKGPGMPPPPMVPGKHNLDVNVWD 194
            :|.....|..::|.|.   |.:.:.||. ::..||....:|......|..|......|...|::.
plant   166 SSVATPTQPDLSANKP---AGVKTLPAD-SNNVASAAGITKGSNGSAPVKPTNQATLNTSSNLYG 226

  Fly   195 LPNNKPPPVPSPPSPIDLGYSDLSSDFSISSNTAP-PL--GARAEKVHKDTENFLKYEHKGLGNN 256
            :        .:|...:..||.|  ..::.....|| |.  |::...|.:..        .|.|..
plant   227 M--------GAPGGGLAAGYQD--PRYAYEGYYAPVPWHDGSKYSDVQRPV--------SGSGVA 273

  Fly   257 NNFSRAKVSPTGPVRRNLGPQQPVHHAA---PRPATN----------------AGPFGPP--NAR 300
            :::|:   |.|.|..||...:...|:.:   |...|.                .|.:|..  :|.
plant   274 SSYSK---SSTVPSSRNQNYRSNSHYTSVHQPSSVTGYGTAQGYYNRMYQNKLYGQYGSTGRSAL 335

  Fly   301 RHDGGPHPSRNSERSGNYSSFRGSEFESASKFEYRDENQSRPVEATSATEELP-----------V 354
            .:....:.||.:.|....:..:...:...:.:.|.:||.   |:..:.....|           :
plant   336 GYGSSGYDSRTNGRGWAATDNKYRSWGRGNSYYYGNENN---VDGLNELNRGPRAKGTKNQKGNL 397

  Fly   355 DSQLVLDE------------------LKDKNNYNPKVLDLKKAGSARFFVIKSYSEDDIHRSIKY 401
            |..|.:.|                  :.|:..||.:...:..| :|.||:||||||||:|:||||
plant   398 DDSLEVKEQTGESNVTEVGEADNTCVVPDREQYNKEDFPVDYA-NAMFFIIKSYSEDDVHKSIKY 461

  Fly   402 EIWCSTDHGNKRLDDAFKERHEEGGN--IMLFFSVNGSGHFCGMAQMMTPVDYNSTSSVWSQDKW 464
            .:|.||.:|||:|..|::|..::.|.  |.||||||.||.|.|:|:|..|||:|:....|.||||
plant   462 NVWASTPNGNKKLAAAYQEAQQKAGGCPIFLFFSVNASGQFVGLAEMTGPVDFNTNVEYWQQDKW 526

  Fly   465 RGKFKVKWIYVKDVPNGTLRHIRLENNENKSVTNSRDTQEVPNDKGIEVLQILHSYNHSTSIFDD 529
            .|.|.:||..||||||..|:||.|||||||.||||||||||..::|:::::|...::..|.|.||
plant   527 TGSFPLKWHIVKDVPNSLLKHITLENNENKPVTNSRDTQEVKLEQGLKIVKIFKEHSSKTCILDD 591

  Fly   530 FFHYEKKQ----------------EEEVS-SKRPPMHGPDGNNHAPAPLARS 564
            |..||.:|                ||:|: .|:........:..:||.:..|
plant   592 FSFYEVRQKTILEKKAKQTQKQVSEEKVTDEKKESATAESASKESPAAVQTS 643

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ythdf	NP_651322.1	YTH	382..518	CDD:461195	80/137 (58%)
ECT2	NP_187955.2	YTH	444..580	CDD:461195	79/135 (59%)