Protein Alignment Ythdf and ECT5

DIOPT Version :10

• Sequence 1: NP_651322.1
• Gene: Ythdf / 42995
• FlyBaseID: FBgn0039261
• Length: 700
• Species: Drosophila melanogaster
• Sequence 2: NP_187912.2
• Gene: ECT5 / 820492
• AraportID: AT3G13060
• Length: 634
• Species: Arabidopsis thaliana
• Alignment Length: 582
• Identity: 173/582 - (29%)
• Similarity: 244/582 - (41%)
• Gaps: 114/582 - (19%)

  Fly    25 SQQVDEASYENLSSPT--HDEVSGNDNSMQFQY-PPFNFKENCNTPWNNMNKGRKANANHDSYRR 86
            |.|.....|....:||  .||.|...|...... .|..|.||.
plant    76 SPQAQGFYYRGYENPTGEWDEYSSYVNVEGLDITSPVGFNENA---------------------- 118

  Fly    87 HGHSIPNNTRRDEHQVNPWNSRKPAAQSFRNENDQPSTKLDNRTSDEAQNQEVVAAPKKTTWASI 151
               |:...|....:...|:....|||....:|....|.:....:......|:||  |....:.:.
plant   119 ---SLVYQTGYGYNPQMPYGPYSPAASPLPSEGQLYSPQQFPFSGASPYYQQVV--PPSMQYITS 178

  Fly   152 ASQPAKLTSRAASTTSNSKKKGP--GMPPPPMVPGKHN------------LDVNVWDLPNNKPPP 202
            .:|| :||| ...........||  ...|.|:.|...|            .|..:|. ..:||..
plant   179 PTQP-ELTS-LVGVDQQGDNIGPRQSYHPHPIGPFNGNQPNLGFPEWQQGFDGGIWS-DWSKPSD 240

  Fly   203 VPSPPSPID--LGYSDLSSDFSISSNTAPPLGARAEK----VHKDTENFLK-YEHK-GLGNNNNF 259
            :....|.|.  |....|.|..|...|.  |:|::.::    ....:.::.: |.|. |.|..:|:
plant   241 MHRHSSSISPALSPQPLGSYGSYGQNI--PMGSQRQRSFYGFGSGSNSYNRGYMHSGGRGQGSNY 303

  Fly   260 SRAKVSPTGPVRRNLGPQQPVHHAAPRPATNAGPFGPPNARRHDGGPHPSRNSERSGNYSSFRGS 324
            ....:|..|     :|              |.|..|..|:|.......||.....:|.:.....
plant   304 GSRLISNVG-----MG--------------NQGWIGVDNSRGRGRVSDPSLGGAYNGTFDILNE- 348

  Fly   325 EFESASKFEYRDENQSRPVEATSATEELPVDSQLVLDELKD-KNNYNPKVLDLKKAGSARF---- 384
                    :.|....|:|  .|...||        ||...| |.|......:.:::.:|.|
plant   349 --------QNRGPRASKP--KTQVLEE--------LDSAADSKKNNKGSAKEHEESNNADFVTDY 395

  Fly   385 -----FVIKSYSEDDIHRSIKYEIWCSTDHGNKRLDDAFKERHEEGGNIMLF--FSVNGSGHFCG 442
                 |:|||||||::|:||||.:|.||.:|||:||.|::|..:|.....||  ||||.|..|||
plant   396 TNAKLFIIKSYSEDNVHKSIKYNVWASTPNGNKKLDAAYREAKDEKEPCPLFLLFSVNASSQFCG 460

  Fly   443 MAQMMTPVDYNSTSSVWSQDKWRGKFKVKWIYVKDVPNGTLRHIRLENNENKSVTNSRDTQEVPN 507
            :|:|:.|||:..:...|.||||.|:|.|||..:|||||...|||.||||:||.||||||||||..
plant   461 VAEMVGPVDFEKSVDYWQQDKWSGQFPVKWHIIKDVPNSQFRHIILENNDNKPVTNSRDTQEVKL 525

  Fly   508 DKGIEVLQILHSYNHSTSIFDDFFHYEKKQE--EEVSSKRPPMHGPDG-----NNHAPAPLA 562
            ::|||:|:|..:|:..|||.|||..||::::  ::..::|.|.....|     |.|.||..|
plant   526 EQGIEMLKIFKNYDADTSILDDFGFYEEREKIIQDRKARRQPSLPSAGVVAGENEHKPASAA 587

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ythdf	NP_651322.1	YTH	382..518	CDD:461195	80/146 (55%)
ECT5	NP_187912.2	YTH	398..536	CDD:461195	78/137 (57%)