Protein Alignment Ythdf and ythdf3

DIOPT Version :9

• Sequence 1: NP_001262943.1
• Gene: Ythdf / 42995
• FlyBaseID: FBgn0039261
• Length: 700
• Species: Drosophila melanogaster
• Sequence 2: NP_956164.1
• Gene: ythdf3 / 334191
• ZFINID: ZDB-GENE-030131-6123
• Length: 600
• Species: Danio rerio
• Alignment Length: 423
• Identity: 178/423 - (42%)
• Similarity: 235/423 - (55%)
• Gaps: 77/423 - (18%)

  Fly   141 AAPKKTTWASIASQPAKLTSRAASTTSNSKKKGPGMPPPPMVPGKHNLDVNVWDLPNN--KPPPV 203
            :|||.|:||:||.:|||...:.....:.....|..:||||:   |||:::..|:...:  |||..
Zfish   230 SAPKPTSWAAIARKPAKPQPKMKPKPNMILGSGVTIPPPPI---KHNINIGTWEDKGSITKPPLA 291

  Fly   204 PSPPSPIDLGYSDLSSDFSISSNTAPPLGARAEKVHKDTENFLKYEHKGLGNNNNFSRAKVSPTG 268
            .....|..|....|      .:...|.|.:.....|:.....|:.:               ||..
Zfish   292 QQMLPPQQLVQQQL------LAQPPPMLQSPLPPQHQPQHQQLQVQ---------------SPQH 335

  Fly   269 PVRRNLGPQQPVHHAAPRPATNAGPFGPPNARRHDGGPHPS--------------RNSERSGNYS 319
            |  ::|.|..|.||:.|         |||...      |||              ||
Zfish   336 P--QHLPPGPPHHHSQP---------GPPQPL------HPSQAQNPLIQNRWVAPRN-------- 375

  Fly   320 SFRGSEFESASKFEYRDENQSRPVEATSATEELPVDSQLVLDELKDKNNYNPKVLD--LKKAGSA 382
              ||:.|...|..:........|:.::.::.|:    ..||::||..||||||..|  ||   :.
Zfish   376 --RGTMFNQNSGMDNFGLGTGVPMSSSPSSNEV----HPVLEKLKALNNYNPKDFDWTLK---NG 431

  Fly   383 RFFVIKSYSEDDIHRSIKYEIWCSTDHGNKRLDDAFKERHEEGGNIMLFFSVNGSGHFCGMAQMM 447
            |.|:|||||||||||||||.|||||:|||||||.|::....: |.:.|.|||||||||||:|:|.
Zfish   432 RVFIIKSYSEDDIHRSIKYSIWCSTEHGNKRLDGAYRSLSAK-GPLYLLFSVNGSGHFCGVAEMK 495

  Fly   448 TPVDYNSTSSVWSQDKWRGKFKVKWIYVKDVPNGTLRHIRLENNENKSVTNSRDTQEVPNDKGIE 512
            :.||||:.:.|||||||:|||:||||:||||||..|||||||||:||.|||||||||||.:|..:
Zfish   496 STVDYNAYAGVWSQDKWKGKFEVKWIFVKDVPNNQLRHIRLENNDNKPVTNSRDTQEVPLEKAKQ 560

  Fly   513 VLQILHSYNHSTSIFDDFFHYEKKQEEEVSSKR 545
            ||:|:.::.|:|||||||.||||:||||.:.:|
Zfish   561 VLKIIATFKHTTSIFDDFAHYEKRQEEEEAMRR 593

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ythdf	NP_001262943.1	YTH	382..518	CDD:309322	95/135 (70%)
ythdf3	NP_956164.1	YTH	432..565	CDD:282058	94/133 (71%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170586505
Domainoid	1	1.000	209	1.000	Domainoid score	I2786
eggNOG	1	0.900	-	-		E1_KOG1901
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	297	1.000	Inparanoid score	I2705
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000639
OrthoInspector	1	1.000	-	-		otm25020
orthoMCL	1	0.900	-	-		OOG6_102335
Panther	1	1.100	-	-	O	PTHR12357
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2345
SonicParanoid	1	1.000	-	-		X383
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	13	12.780