Protein Alignment Ythdf and ythdf2

DIOPT Version :9

• Sequence 1: NP_001262943.1
• Gene: Ythdf / 42995
• FlyBaseID: FBgn0039261
• Length: 700
• Species: Drosophila melanogaster
• Sequence 2: XP_031752749.1
• Gene: ythdf2 / 100379960
• XenbaseID: XB-GENE-977191
• Length: 517
• Species: Xenopus tropicalis
• Alignment Length: 411
• Identity: 165/411 - (40%)
• Similarity: 210/411 - (51%)
• Gaps: 134/411 - (32%)

  Fly   140 VAAPKKTTWASIASQPAKLTSRAASTTSNSKKKGPGMPPPPMVPGKHNLDVNVWDLPNNKPPPVP 204
            ||.||:.:||.|||:|||.|....            :||||  |.|||:::..||   ||
 Frog   232 VAPPKQASWADIASKPAKQTLAKI------------LPPPP--PSKHNMEIGTWD---NK----- 274

  Fly   205 SPPSPIDLGYSDLSSDFSISSNTAPPLGARAEKVHKDTENFLKYEHKGLGNNNNFSRAKVSPTGP 269
                         .|..|:...::||:                       ...:...|.::|..|
 Frog   275 -------------VSTVSVCQASSPPI-----------------------LQQSIPNAAIAPHAP 303

  Fly   270 VR----RNLGPQQPVHHAAPRPATNAGPFGPPNARRHDGGPHPSRNSERSGNYSSFRGSEFESAS 330
            .|    ||...:|    ..|.|.|              ..|||
 Frog   304 TRWSAHRNRSSEQ----TQPPPLT--------------AEPHP---------------------- 328

  Fly   331 KFEYRDENQSRPVEATSATEELPVDSQLVLDELKDKNNYNPKVLDLK-KAGSARFFVIKSYSEDD 394
                                        ||::|:..||||||..|.. |.|  |.|::|||||||
 Frog   329 ----------------------------VLEKLRSVNNYNPKDFDFSLKLG--RVFIVKSYSEDD 363

  Fly   395 IHRSIKYEIWCSTDHGNKRLDDAFKERHEEGGNIMLFFSVNGSGHFCGMAQMMTPVDYNSTSSVW 459
            |||||||.:||||:|||||||.|::..:.: |.:.|.|||||||||||:|:|.:.||||:.:.||
 Frog   364 IHRSIKYNVWCSTEHGNKRLDAAYRSLNGK-GPLYLLFSVNGSGHFCGVAEMRSAVDYNTCAGVW 427

  Fly   460 SQDKWRGKFKVKWIYVKDVPNGTLRHIRLENNENKSVTNSRDTQEVPNDKGIEVLQILHSYNHST 524
            |||||:|:|.|:|::|||||||.|||||||||:||.|||||||||||.:|..:||:|:.||.|:|
 Frog   428 SQDKWKGRFDVRWLFVKDVPNGQLRHIRLENNDNKPVTNSRDTQEVPLEKARQVLRIIASYKHTT 492

  Fly   525 SIFDDFFHYEKKQEEEVSSKR 545
            ||||||.||||:||||.|.|:
 Frog   493 SIFDDFSHYEKRQEEEDSVKK 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ythdf	NP_001262943.1	YTH	382..518	CDD:309322	91/135 (67%)
ythdf2	XP_031752749.1	SPT5	<112..321	CDD:227493	37/150 (25%)
		YTH	352..485	CDD:398013	90/133 (68%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	208	1.000	Domainoid score	I2802
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	278	1.000	Inparanoid score	I2858
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000639
OrthoInspector	1	1.000	-	-		otm48549
Panther	1	1.100	-	-	O	PTHR12357
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2345
SonicParanoid	1	1.000	-	-		X383
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.090