Protein Alignment Ythdf and ythdf3

DIOPT Version :9

• Sequence 1: NP_001262943.1
• Gene: Ythdf / 42995
• FlyBaseID: FBgn0039261
• Length: 700
• Species: Drosophila melanogaster
• Sequence 2: NP_001120433.1
• Gene: ythdf3 / 100145519
• XenbaseID: XB-GENE-5752937
• Length: 572
• Species: Xenopus tropicalis
• Alignment Length: 421
• Identity: 177/421 - (42%)
• Similarity: 226/421 - (53%)
• Gaps: 100/421 - (23%)

  Fly   141 AAPKKTTWASIASQPAKLTSRAASTTSNSKKKGPGMPPPPMVPGKHNLDVNVWDLPNN--KPPPV 203
            :|||.|:||:||.:|||...: ....:|.......:||||:   |||:::..||....  |.||:
 Frog   229 SAPKPTSWAAIARKPAKPQPK-LKPKNNVGIGSSAVPPPPI---KHNINIGTWDDKGAIVKTPPI 289

  Fly   204 PS--PPSPIDLGYSDLSSDFSISSNTAPPLGARAEKVHKDTENFLKYEHKGLGNNNNFSRAKVSP 266
            .|  ||.|:......|:....:..|..|....:.:
 Frog   290 QSVLPPQPVIQQPQPLTQPLPMVQNQLPQQQLQQQ------------------------------ 324

  Fly   267 TGPVRRNLGPQQPVHH---------AAPRPATNAGP-FGPPNARRHDGGPHPSRNSERSGNYSSF 321
                    |||||.|.         .|||   |.|. |...|.               |||
 Frog   325 --------GPQQPPHQIQQQLQNRWVAPR---NRGAGFNQNNV---------------SGN---- 359

  Fly   322 RGSEFESASKFEYRDENQSRPVEATSATEELPVDSQLVLDELKDKNNYNPKVLD--LKKAGSARF 384
                           ||.|..|...|::.. .|:...||::||..||||||..|  ||   :.|.
 Frog   360 ---------------ENFSLGVVPVSSSPS-GVEVHPVLEKLKAINNYNPKDFDWSLK---NGRV 405

  Fly   385 FVIKSYSEDDIHRSIKYEIWCSTDHGNKRLDDAFKERHEEGGNIMLFFSVNGSGHFCGMAQMMTP 449
            |:|||||||||||||||.|||||:|||||||.|::..:.: |.:.|.|||||||||||:|:|.:.
 Frog   406 FIIKSYSEDDIHRSIKYTIWCSTEHGNKRLDAAYRSLNGK-GPLYLLFSVNGSGHFCGVAEMKSV 469

  Fly   450 VDYNSTSSVWSQDKWRGKFKVKWIYVKDVPNGTLRHIRLENNENKSVTNSRDTQEVPNDKGIEVL 514
            ||||:.:.|||||||:|||.|||::||||||..|||||||||:||.|||||||||||.:|..:||
 Frog   470 VDYNAYAGVWSQDKWKGKFDVKWVFVKDVPNNQLRHIRLENNDNKPVTNSRDTQEVPLEKAKQVL 534

  Fly   515 QILHSYNHSTSIFDDFFHYEKKQEEEVSSKR 545
            :|:.::.|:|||||||.||||:||||.:.:|
 Frog   535 KIIATFKHTTSIFDDFAHYEKRQEEEEAMRR 565

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ythdf	NP_001262943.1	YTH	382..518	CDD:309322	94/135 (70%)
ythdf3	NP_001120433.1	YTH	404..537	CDD:367840	93/133 (70%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	208	1.000	Domainoid score	I2802
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	278	1.000	Inparanoid score	I2858
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000639
OrthoInspector	1	1.000	-	-		otm48549
Panther	1	1.100	-	-	O	PTHR12357
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2345
SonicParanoid	1	1.000	-	-		X383
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	9.090