| Sequence 1: | NP_524493.1 | Gene: | Hr96 / 42993 | FlyBaseID: | FBgn0015240 | Length: | 723 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_068370.1 | Gene: | NR1D1 / 9572 | HGNCID: | 7962 | Length: | 614 | Species: | Homo sapiens |
| Alignment Length: | 750 | Identity: | 142/750 - (18%) |
|---|---|---|---|
| Similarity: | 225/750 - (30%) | Gaps: | 318/750 - (42%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 1 MSPPKN-------------CAVCGDKALGYNFNAVTCESCKAFFRRNALAKKQF-TCPFNQNCDI 51
Fly 52 TVVTRRFCQKCRLRKCLDIGMKSENIMSEEDKLIKRRKIETNRAKRRLMENGTDACDADGGEERD 116
Fly 117 HKAPADSSSSNLDHYSGSQDSQSCGSADS-------GANGCSGRQASSPGTQVN----PLQMTAE 170
Fly 171 KIVDQIVSDPDRASQAINRLMRTQKEAISVMEKVISSQKDALRLVSHLIDYPGDALKIISKFMNS 235
Fly 236 PFNALTVFTKFMSSPTDGVE-IISKIVDSPADVVEFMQNLMHSPEDAIDIMNKFMNTPAEALRIL 299
Fly 300 NRILSGGGANAAQQTADRKPLLDKEPAVKPAAPAERADTVIQSMLGNSPPISPHDAAVDLQYHSP 364
Fly 365 GVGEQPSTSSSHPLPYIANSPDFDLKTFMQTNYNDEPSLDSDFSINSIESVLSEVIRIEYQAFNS 429
Fly 430 IQQAASRVKEEMSYGTQSTYGGCNSAANNSQPHLQQPICAPSTQQLDRELNEAEQMKLRELRLA- 493
Fly 494 ---------SEALYDPVDEDLSALMMGDDRIKPDDTRHNPKLLQLINLTAVAIKRLIKMAKKITA 549
Fly 550 FRDMCQEDQVALLKGGCTEMMIMRSVMIYDDDRAAWKVPHTKENMGNIRTDLLKFAEGNIYEEHQ 614
Fly 615 ----------KFITTFDEKWR---MDENIILIMCAIVLFTSARSRVIHKDVIRLEQNSYYYLLR- 665
Fly 666 -----RYLESVYSGCEARNAFIKLIQKISDVERLN 695 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Hr96 | NP_524493.1 | NR_DBD_CAR | 5..98 | CDD:143524 | 35/106 (33%) |
| NR_LBD | 462..>573 | CDD:299703 | 27/120 (23%) | ||
| NR_LBD_F1 | 523..702 | CDD:132727 | 42/191 (22%) | ||
| NR1D1 | NP_068370.1 | Modulating | 1..128 | 3/14 (21%) | |
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..119 | 3/5 (60%) | |||
| Required for phosphorylation by CSNK1E and cytoplasmic localization. /evidence=ECO:0000250|UniProtKB:Q3UV55 | 1..70 | ||||
| Crucial for activation of GJA1. /evidence=ECO:0000250 | 49..284 | 62/276 (22%) | |||
| NR_DBD_REV_ERB | 127..215 | CDD:143540 | 34/95 (36%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 233..285 | 17/126 (13%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 311..345 | 10/85 (12%) | |||
| NR_LBD | 418..611 | CDD:325017 | 46/230 (20%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C165157566 | |
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.840 | |||||