DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hr96 and Nr1h5

DIOPT Version :9

Sequence 1:	NP_524493.1	Gene:	Hr96 / 42993	FlyBaseID:	FBgn0015240	Length:	723	Species:	Drosophila melanogaster
Sequence 2:	XP_003749414.1	Gene:	Nr1h5 / 690430	RGDID:	1596077	Length:	504	Species:	Rattus norvegicus

Alignment Length:	218	Identity:	61/218 - (27%)
Similarity:	105/218 - (48%)	Gaps:	30/218 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 CAVCGDKALGYNFNAVTCESCKAFFRRNALAKKQFTCPFNQNCDITVVTRRFCQKCRLRKCLDIG 71
            |.||||||.||::||:|||.||.||||:......::|....:|::.:..||.|.:|||:||..:|
  Rat   121 CMVCGDKASGYHYNALTCEGCKGFFRRSITKNAVYSCKNGGHCEMDMYMRRKCPECRLKKCKAVG 185

  Fly    72 MKSENIMSEEDKLIKRRKIETNRAKRRLMENGTDACDADGGEERDHKAPADSSSSNLDHYSGSQD 136
            |.:|.:::|..  .|.:::..:...|..:.:.....|    |..|.|..:.:|.|.    .|:||
  Rat   186 MLAECLLTEIQ--CKSKRLRKSFKHRPTLSSAIQVED----EGTDTKHVSSTSRSG----KGAQD 240

  Fly   137 SQSCGSADS---GANGCSGRQASSPGTQVNPLQMTAEKIVDQIVSDPD----RASQA----INRL 190
            ..:..:.:.   .....:.|::..|..:::.|.        |..|:|:    |.|:|    .|.|
  Rat   241 DMTLTAEERRLLNTIVTAHRKSMVPVGEISALL--------QEYSNPELSFLRLSEASILHANWL 297

  Fly   191 MRTQKEAISVMEKVISSQKDALR 213
            |:..| .:...|.:.:..:.||:
  Rat   298 MKFTK-GLPGFENLTAEDQTALQ 319

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hr96	NP_524493.1	NR_DBD_CAR	5..98	CDD:143524	35/90 (39%)
		NR_LBD	462..>573	CDD:299703
		NR_LBD_F1	523..702	CDD:132727
Nr1h5	XP_003749414.1	NR_DBD_FXR	118..201	CDD:143520	35/81 (43%)
Nr1h5	XP_003749414.1	NR_LBD	247..496	CDD:299703	16/82 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351536
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24082
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.940