Protein Alignment Hr96 and RORC

DIOPT Version :9

• Sequence 1: NP_524493.1
• Gene: Hr96 / 42993
• FlyBaseID: FBgn0015240
• Length: 723
• Species: Drosophila melanogaster
• Sequence 2: XP_006711547.2
• Gene: RORC / 6097
• HGNCID: 10260
• Length: 651
• Species: Homo sapiens
• Alignment Length: 771
• Identity: 134/771 - (17%)
• Similarity: 227/771 - (29%)
• Gaps: 354/771 - (45%)

  Fly     7 CAVCGDKALGYNFNAVTCESCKAFFRRNALAKKQFTCPFNQNCDITVVTRRFCQKCRLRKCLDIG 71
            |.:||||:.|.::..:|||.||.||||:......::|...|||.|...:|..||.|||:|||.:|
Human   164 CKICGDKSSGIHYGVITCEGCKGFFRRSQRCNAAYSCTRQQNCPIDRTSRNRCQHCRLQKCLALG 228

  Fly    72 MKSENI----MSEEDKLIKRRKIETNRAKRRLMEN----GTDACDADGGEE-------RDHKAPA 121
            |..:.:    ||::.:.....:::....:|:..:.    .|....|.|.:.       .|.:.|.
Human   229 MSRDAVKFGRMSKKQRDSLHAEVQKQLQQRQQQQQEPVVKTPPAGAQGADTLTYTLGLPDGQLPL 293

  Fly   122 DSSSS---------NLDHYSGSQDSQSCGSADSGANGCSGRQASSPGTQVNPLQMTAEKIVDQIV 177
            .||..         .|...|||..|.|...|.:|.||.|
Human   294 GSSPDLPEASACPPGLLKASGSGPSYSNNLAKAGLNGAS-------------------------- 332

  Fly   178 SDPDRASQAINRLMRTQKEAISVMEKVISSQKDALRLVSHLIDYPGDALKIISKFMNSPFNALTV 242
                                                                             
Human   333 ----------------------------------------------------------------- 332

  Fly   243 FTKFMSSPTDGVEIISKIVDSPADVVEFMQNLMHSPE-DAIDIMNKFMNTPAEALRILNRILSGG 306
                                         .:|.:||| ...:....|.:|
Human   333 -----------------------------CHLEYSPERGKAEGRESFYST--------------- 353

  Fly   307 GANAAQQTADRKPLLDKEPAVKPAAPAERADTVIQSMLGNSPPISPHDAAVDLQYHSPGVGEQPS 371
               .:|.|.||..|..:|                                    :..||:||...
Human   354 ---GSQLTPDRCGLRFEE------------------------------------HRHPGLGELGQ 379

  Fly   372 TSSSHPLPYIANSPDFDLKTFMQTNYNDEPSLDSDFSINSIESVLSEVIRIEYQAFNSIQQAASR 436
            ...|:..|...::|:                                   ..|.:...|:
Human   380 GPDSYGSPSFRSTPE-----------------------------------APYASLTEIE----- 404

  Fly   437 VKEEMSYGTQSTYGGCNSAANNSQPHLQQPICAPSTQQLDRELNEAEQMKLRELRLASEALYDPV 501
                                     ||.|.:|        :...|..|::|.:|......::.
Human   405 -------------------------HLVQSVC--------KSYRETCQLRLEDLLRQRSNIFS-- 434

  Fly   502 DEDLSALMMGDDRIKPDDTRHNPKLLQLI------NLTAVAIKRLIKMAKKITAFRDMCQEDQVA 560
                          :.:.|.:..|.:..:      :||. ||:.:::.||:::.|.::||.||:.
Human   435 --------------REEVTGYQRKSMWEMWERCAHHLTE-AIQYVVEFAKRLSGFMELCQNDQIV 484

  Fly   561 LLKGGCTEMMIMRSVMIYDDDRAAWKVPHTKENMGNIRTDLLKFAEG------------------ 607
            |||.|..|::::|....|:.|.               ||   .|.||
Human   485 LLKAGAMEVVLVRMCRAYNADN---------------RT---VFFEGKYGGMELFRALGCSELIS 531

  Fly   608 NIYE-EHQKFITTFDEKWRMDENIILIMCAIVLFTSAR-----SRVIHKDVIRLEQNSYYYLLRR 666
            :|:: .|......|.|    ||  |.:..|:||..:.|     .|.:.:....||...:::|.:.
Human   532 SIFDFSHSLSALHFSE----DE--IALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKT 590

  Fly   667 YLESVYSGCEARNAFIKLIQKISDVERLNKFIINVYLNVNPSQVE----PLLREIF 718
            :.:|:.:....:.....|..:  .||||     .::.:::|..|:    ||.:|:|
Human   591 HRQSILAKLPPKGKLRSLCSQ--HVERL-----QIFQHLHPIVVQAAFPPLYKELF 639

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hr96	NP_524493.1	NR_DBD_CAR	5..98	CDD:143524	33/94 (35%)
		NR_LBD	462..>573	CDD:299703	26/116 (22%)
		NR_LBD_F1	523..702	CDD:132727	46/208 (22%)
RORC	XP_006711547.2	NR_DBD_ROR	157..251	CDD:143526	33/86 (38%)
		NR_LBD_ROR_like	401..639	CDD:132737	61/323 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157564
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840