Protein Alignment Hr96 and vdrb

DIOPT Version :10

• Sequence 1: NP_524493.1
• Gene: Hr96 / 42993
• FlyBaseID: FBgn0015240
• Length: 723
• Species: Drosophila melanogaster
• Sequence 2: XP_073809191.1
• Gene: vdrb / 564511
• ZFINID: ZDB-GENE-080403-10
• Length: 431
• Species: Danio rerio
• Alignment Length: 747
• Identity: 157/747 - (21%)
• Similarity: 235/747 - (31%)
• Gaps: 381/747 - (51%)

  Fly     4 PKNCAVCGDKALGYNFNAVTCESCKAFFRRNALAKKQFTCPFNQNCDITVVTRRFCQKCRLRKCL 68
            |:.|.||||||.|::|||:|||.||.||||:...|..||||||.:|.||...||.||.|||::||
Zfish    29 PRICGVCGDKATGFHFNAMTCEGCKGFFRRSMKRKASFTCPFNGSCTITKDNRRHCQACRLKRCL 93

  Fly    69 DIGMKSENIMSEED-----KLIKRRKIETNRAKRRLMENGTDACDADGGEERDHKAPADSSSSNL 128
            ||||..|.|:::|:     :||:|||                       :|..|
Zfish    94 DIGMMKEFILTDEEVQRKKELIQRRK-----------------------DEEAH----------- 124

  Fly   129 DHYSGSQDSQSCGSADSGANGCSGRQASSPGTQVNPLQMTAEKIVDQIVSDPDRASQAINRLMRT 193
                                    |:|..|.                 :||..|
Zfish   125 ------------------------REAQKPR-----------------LSDEQR----------- 137

  Fly   194 QKEAISVMEKVISSQKDALRLVSHLIDYPGDALKIISKFMNSPFNALTVFTKFMSSPTDGVEIIS 258
                                                                         .||.
Zfish   138 -------------------------------------------------------------NIID 141

  Fly   259 KIVDSPADVVEFMQNLMHSPEDAIDIMNKFMNTPAEALRILNRILSGGGANAAQQTADRKPLLDK 323
            .:||                                               |..:|.|
Zfish   142 TLVD-----------------------------------------------AHHKTYD------- 152

  Fly   324 EPAVKPAAPAERADTVIQSMLGNSPPISPHDAAVDLQYHSPGVGEQPSTSSSHPLPYIANSPDFD 388
                                          |:..|.....|.|.|.|.|.|
Zfish   153 ------------------------------DSYSDFSRFRPPVREGPVTRS-------------- 173

  Fly   389 LKTFMQTNYNDEPSLDSDFSINSIESVLSEVIRIEYQAFNSIQQAASRVKEEMSYGTQSTYGGCN 453
                                                         |||.         ::....:
Zfish   174 ---------------------------------------------ASRA---------ASLHSLS 184

  Fly   454 SAANNSQPHLQQPICAPSTQQLDRELNEAE-QMKLRELRLASEALYDPVDEDLSALMMGDDRIKP 517
            .|:::|..|        |.:..||::|.:. .|..:|..|:|..  |..:||.|:|.|
Zfish   185 DASSDSFSH--------SPESGDRKMNLSNLLMMYQEQGLSSSP--DSKEEDGSSLSM------- 232

  Fly   518 DDTRHNPKLLQLINLTAVAIKRLIKMAKKITAFRDMCQEDQVALLKGGCTEMMIMRSVMIYDDDR 582
                    |..|.:|.:.:|:::|..||.|..||::..|||:||||....|::::||...:..:.
Zfish   233 --------LPHLADLVSYSIQKVIGFAKMIPGFRELTAEDQIALLKSSAIEVIMLRSNQSFSLED 289

  Fly   583 AAW---------------KVPHTKENMGNIRTDLLKFAEG----NIYEEHQKFITTFDEKWRMDE 628
            .:|               |..||.|    :...|:||..|    |::||               |
Zfish   290 MSWSCGGPEFKYCVNDVTKAGHTLE----LLEPLVKFQVGLKKLNLHEE---------------E 335

  Fly   629 NIILIMCAIVLFTSARSRVIHKDVIRLE--QNSYYYLLRRYLESVYSGCEARNAFIKLIQKISDV 691
            :::|:  ||.|.:..|..|  :|.:|:|  |:....:|:.|:.:.:.|  .|..:.|:|||::|:
Zfish   336 HVLLM--AICLLSPDRPGV--QDHVRVEALQDKVSEVLQAYIRAHHPG--GRLLYAKMIQKLADL 394

  Fly   692 ERLNKFIINVY--LNVNPS---QVEPLLREIF 718
            ..||:.....|  |:..|.   |:.||:.|:|
Zfish   395 RSLNEEHSKQYRSLSFQPEHSMQLTPLVLEVF 426

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hr96	NP_524493.1	NR_DBD_CAR	5..98	CDD:143524	51/97 (53%)
		NR_LBD	462..>573	CDD:472173	33/111 (30%)
		NR_LBD_F1	523..702	CDD:132727	54/199 (27%)
vdrb	XP_073809191.1	None