DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hr96 and nr1h5

DIOPT Version :9

Sequence 1:	NP_524493.1	Gene:	Hr96 / 42993	FlyBaseID:	FBgn0015240	Length:	723	Species:	Drosophila melanogaster
Sequence 2:	XP_005166790.1	Gene:	nr1h5 / 557500	ZFINID:	ZDB-GENE-080403-3	Length:	487	Species:	Danio rerio

Alignment Length:	236	Identity:	69/236 - (29%)
Similarity:	102/236 - (43%)	Gaps:	64/236 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 CAVCGDKALGYNFNAVTCESCKAFFRRNALAKKQFTCPFNQNCDITVVTRRFCQKCRLRKCLDIG 71
            |.||||||.||::||:|||.||.||||:...|..:.|....:|::.:..||.||.||||||..:|
Zfish   130 CVVCGDKASGYHYNALTCEGCKGFFRRSVTKKAVYHCKSGGSCEMDMYMRRKCQDCRLRKCRAVG 194

  Fly    72 MKSENIMSEEDKLIKR-RKIETNRAKRRLMENGTDACDADGGEERDHKAPADSSSSNLDHYSGSQ 135
            |.:|.:::|.....|| ||                     |.:.|.|..   ||:...|.||.|:
Zfish   195 MLAECLLTEVQCQSKRLRK---------------------GSKHRGHNG---SSARAEDDYSESR 235

  Fly   136 DSQSCGSADSG-ANGCSGRQ---------------------------ASSPGTQVNPLQMTAEKI 172
            ...|....::. ::|.|..|                           :|...|.:.|.|  .||:
Zfish   236 SVSSTSRINTRVSSGFSREQRCILNRIVEAFRRYIIQDNTHCRVPLWSSLTNTHLTPPQ--TEKL 298

  Fly   173 VDQIVSDP-----DRASQAINRLMRTQKEAISVMEKVISSQ 208
            :..:.|.|     |.:.|  |.|:  ...::.||..:::.|
Zfish   299 LQFLRSVPGFDLLDSSDQ--NTLL--SSASVEVMFLLLAQQ 335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hr96	NP_524493.1	NR_DBD_CAR	5..98	CDD:143524	41/91 (45%)
		NR_LBD	462..>573	CDD:299703
		NR_LBD_F1	523..702	CDD:132727
nr1h5	XP_005166790.1	NR_DBD_like	127..210	CDD:295381	37/79 (47%)
nr1h5	XP_005166790.1	NR_LBD	288..478	CDD:299703	14/54 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593333
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D153746at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24082
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.950