Protein Alignment Hr96 and nr1d1

DIOPT Version :9

• Sequence 1: NP_524493.1
• Gene: Hr96 / 42993
• FlyBaseID: FBgn0015240
• Length: 723
• Species: Drosophila melanogaster
• Sequence 2: NP_991292.2
• Gene: nr1d1 / 494487
• ZFINID: ZDB-GENE-050105-1
• Length: 637
• Species: Danio rerio
• Alignment Length: 726
• Identity: 150/726 - (20%)
• Similarity: 245/726 - (33%)
• Gaps: 267/726 - (36%)

  Fly     7 CAVCGDKALGYNFNAVTCESCKAFFRRNALAKKQF-TCPFNQNCDITVVTRRFCQKCRLRKCLDI 70
            |.||||.|.|:::....||.||.||||:.....|: .|..|:.|.|..:.|..||:||.:|||.:
Zfish   128 CKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKKCLKNETCTIMRINRNRCQQCRFKKCLSV 192

  Fly    71 GMKSENIMSEEDKLIKRRKIETNRAKRRLMENGTDACDADGGEERDHKAPADSSSSNLDHYSGSQ 135
            ||..:        .::..:| ..|.|:|::....:|.:.....:..::....|.:||
Zfish   193 GMSRD--------AVRFGRI-PKREKQRMLAEMQNAMNNMVNNQLQNEFQLASITSN-------- 240

  Fly   136 DSQSCGSADSGANGCSGRQASSPGTQVNPLQMTAEKIVDQIVSDPDRASQAINRLMRTQKEAISV 200
              ..|.|:.|.:|..|...:..||..|.|                           :.|..|:.|
Zfish   241 --TPCPSSSSPSNTSSSSSSPCPGLTVGP---------------------------QPQPPAVPV 276

  Fly   201 MEKVISSQKDALRLVSHLIDYPGDALKIISKFMNSPFNALTVFTKFMSSPTDGVEIISKIVDSPA 265
            .:                                              ||:           |||
Zfish   277 AQ----------------------------------------------SPS-----------SPA 284

  Fly   266 DVVEFMQNLMHSPEDAIDIMNKFMNTPAEALRILNRILSGGGANAAQQTADRKPLLDKEPAVKPA 330
            .....:| |..||.       ...:||...                     ..|.:||..|   |
Zfish   285 PTSPTVQ-LAQSPP-------PLTSTPPPC---------------------TSPGVDKTIA---A 317

  Fly   331 APAERADTVI--QSMLGNSPPISPHDAAVDLQ--------YHSPGVGEQPSTSSSHPLPYIANSP 385
            ......:|.|  ...||:  |:.||::.:|.:        ||..|          |
Zfish   318 ITRAHRETFIYAHDKLGS--PLLPHNSELDNRSNNRCMAGYHLNG----------H--------- 361

  Fly   386 DFDLKTFMQTNYNDEPSLDSDFSINSIESVLSEVIRIEYQAFNSIQQAASRVKEEMSYGTQSTYG 450
                    .|.|:.:            .:|.......|.|..||:...||:..|:
Zfish   362 --------NTIYHHD------------NNVAHHCNNFEVQQDNSLHFQASQTPEK---------- 396

  Fly   451 GCNSAANNSQPHLQQPICAPSTQ----QLDRELNEAEQ------MKLRELRLASEALYDPVDEDL 505
              :...||:.   |:|   |::.    ...:|:|.|.|      .|.:|:.||......|..:
Zfish   397 --HQQHNNNS---QRP---PNSNFYSIHHGQEMNSASQGQNCPWKKHKEILLACPMNMHPYSD-- 451

  Fly   506 SALMMGDDRIKPDDTRHNPKLLQLINLT-AVAIKRLIKMAKKITAFRDMCQEDQVALLKGGCTEM 569
                       |:.|..  ::.:..:|: ..|::.:::.||.|..|..:.|.|||.|||.|..|:
Zfish   452 -----------PNKTPQ--EIWEDFSLSFTPAVREVVEFAKHIPGFSTLSQNDQVTLLKAGTFEV 503

  Fly   570 MIMRSVMIYDDDRAAWKVPHTKENMGNIRTDLLKFAEGNIYE-EHQKFI-------TTFD--EK- 623
            :::|...::                 |::...:.|..|..|. |..|.:       |.||  ||
Zfish   504 LMVRFSSLF-----------------NVKEKTVTFISGATYSLEALKSMGMGDLLGTMFDFSEKL 551

  Fly   624 --WRMDENIILIMCAIVLFTSARSRVIHKDVIRLEQNSYYYLLRRYLESVYSGCEARNA--FIKL 684
              ..:....:.:..|:||.::.||.:.:.:.:.:.|.|    |.|.|.::.|.....:|  |.||
Zfish   552 NSLELSAEELGLFTAVVLVSADRSGIENVNSVEMLQES----LIRALRTLVSKSAPTDASRFTKL 612

  Fly   685 IQKISDVERLN 695
            :.|:.|:..||
Zfish   613 LLKLPDLRTLN 623

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hr96	NP_524493.1	NR_DBD_CAR	5..98	CDD:143524	33/91 (36%)
		NR_LBD	462..>573	CDD:299703	29/121 (24%)
		NR_LBD_F1	523..702	CDD:132727	46/189 (24%)
nr1d1	NP_991292.2	NR_DBD_REV_ERB	123..211	CDD:143540	33/91 (36%)
		NR_LBD_REV_ERB	448..635	CDD:132738	49/212 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593349
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840