Protein Alignment Hr96 and nr1d2a

DIOPT Version :9

• Sequence 1: NP_524493.1
• Gene: Hr96 / 42993
• FlyBaseID: FBgn0015240
• Length: 723
• Species: Drosophila melanogaster
• Sequence 2: NP_001124064.2
• Gene: nr1d2a / 402815
• ZFINID: ZDB-GENE-040504-1
• Length: 504
• Species: Danio rerio
• Alignment Length: 709
• Identity: 132/709 - (18%)
• Similarity: 215/709 - (30%)
• Gaps: 324/709 - (45%)

  Fly     7 CAVCGDKALGYNFNAVTCESCKAFFRRNALAKKQF-TCPFNQNCDITVVTRRFCQKCRLRKCLDI 70
            |.||||.|.|:::....||.||.||||:.....|: .|...::|.|..:.|..||:||.:|||.:
Zfish    86 CKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKKCLKTESCTIVRINRNRCQQCRFKKCLSV 150

  Fly    71 GMKSENIMSEEDKLIKRRK----IETNRAKRRLMENGTDACDADGGEERDHKAPADSSSSNLDHY 131
            ||..:.:  ...::.||.|    :|...|...:|.|..       .:...|.:|:|||||:
Zfish   151 GMSRDAV--RFGRIPKREKQRMLLEMQTAMNNMMNNSQ-------LQHMLHVSPSDSSSSS---- 202

  Fly   132 SGSQDSQSCGSADSGANGCSGRQASSPGTQVNPLQMTAEKIVDQIVSDPDRASQAINRLMRTQKE 196
                                   ::||                     ||..        |:..|
Zfish   203 -----------------------SASP---------------------PDSP--------RSSTE 215

  Fly   197 AISVMEKVISSQKDALRLVSHLIDYPGDALKIISKFMNSPFNALTVFTKFMSSPTDGVEIISKIV 261
            ::..|:...|...|                                     |...||
Zfish   216 SLVPMDTASSCSSD-------------------------------------SGEEDG-------- 235

  Fly   262 DSPADVVEFMQNLMHSPEDAIDIMNKFMNTPAEALRILNRILSGGGANAAQQTADRKPLLDKEPA 326
                   .|..:...||                               ||.:|..|:   ::||.
Zfish   236 -------RFSYSASVSP-------------------------------AASETLSRE---EEEPQ 259

  Fly   327 VKPAAPAERADTVIQSMLGNSPPISPHDAAVDLQYHSPGVGEQPSTSSSHPLPYIANSPDFDLKT 391
            ::   ...|:|  .|:..|                                 ||
Zfish   260 MQ---CWRRSD--CQNTTG---------------------------------PY----------- 275

  Fly   392 FMQTNYNDEPSLDSDFSINSIESVLSEVIRIEYQAFNSIQQAASRVKEEMSYGTQSTYGGCNSAA 456
                                .|....:.||:.              .|.|||..::...|.|.|
Zfish   276 --------------------REQTAQQCIRLP--------------TENMSYCRRNMNEGGNRA- 305

  Fly   457 NNSQPHLQQPICAPSTQQLDRELNEAEQMKLRELRLASEALYDPVDEDLSALMMGDDRIKPDDTR 521
                 ||..|:.|.......|..:|                   |.|:.|...:
Zfish   306 -----HLVCPMSASPFVDASRPGHE-------------------VWEEFSRSFI----------- 335

  Fly   522 HNPKLLQLINLTAVAIKRLIKMAKKITAFRDMCQEDQVALLKGGCTEMMIMRSVMIYDDDRAAWK 586
                         .|::.:::.||:|..|:::.|.|||.|||.|..|::::|.|.::|
Zfish   336 -------------PAVREVVEFAKRIPGFQELSQHDQVNLLKAGTFEVLMVRFVPLFD------- 380

  Fly   587 VPHTKENMGNIRTDLLKFAEGNIYE----------EHQKFITTFDEK---WRMDENIILIMCAIV 638
                      ::...:.|..|..|.          |....:..|.||   .::::..:.:..|:|
Zfish   381 ----------VQQRTVSFMSGRRYSVDLLRSMGAGELLNCMFEFSEKLAALQLNDEEMSLFSAVV 435

  Fly   639 LFTSARSRVIHKDVIRLE--QNSYYYLLRRYLESVYSGCEARNAFIKLIQKISDVERLN 695
            |.::.||.:  :||:.:|  |.|....||..:...:|  ...:.|.||:.|:.::..||
Zfish   436 LVSADRSAI--EDVVGVEALQESLIRALRNLIMKNHS--NESSVFTKLLLKLPELRSLN 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hr96	NP_524493.1	NR_DBD_CAR	5..98	CDD:143524	34/95 (36%)
		NR_LBD	462..>573	CDD:299703	23/110 (21%)
		NR_LBD_F1	523..702	CDD:132727	43/188 (23%)
nr1d2a	NP_001124064.2	NR_DBD_REV_ERB	81..169	CDD:143540	32/84 (38%)
		NR_LBD	314..502	CDD:299703	48/241 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593343
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840