Protein Alignment Hr96 and Rorc

DIOPT Version :9

• Sequence 1: NP_524493.1
• Gene: Hr96 / 42993
• FlyBaseID: FBgn0015240
• Length: 723
• Species: Drosophila melanogaster
• Sequence 2: XP_006232988.2
• Gene: Rorc / 368158
• RGDID: 1595785
• Length: 508
• Species: Rattus norvegicus
• Alignment Length: 751
• Identity: 134/751 - (17%)
• Similarity: 232/751 - (30%)
• Gaps: 324/751 - (43%)

  Fly     7 CAVCGDKALGYNFNAVTCESCKAFFRRNALAKKQFTCPFNQNCDITVVTRRFCQKCRLRKCLDIG 71
            |.:||||:.|.::..:|||.||.||||:......::|...|||.|...:|..||.|||:|||.:|
  Rat    31 CKICGDKSSGIHYGVITCEGCKGFFRRSQQCNVAYSCTRQQNCPIDRTSRNRCQHCRLQKCLALG 95

  Fly    72 MKSENI----MSEEDKLIKRRKIETNRAKRRLMENGTDACDADGGEERDHKA---PADS-SSSNL 128
            |..:.:    ||:     |:|.......:::|.:.          ::|:..|   ||.| .:..|
  Rat    96 MSRDAVKFGRMSK-----KQRDSLHAEVQKQLQQQ----------QQREQVAKTPPAGSHGADTL 145

  Fly   129 DHYSGSQDSQSCGSADSGANGCSGRQASSPGTQVNPLQMTAEKIVDQIVSDPDRASQA----INR 189
            .:..|..|.|....|.......|   |..||..                    |||.:    .|.
  Rat   146 TYTLGVPDGQLPLGASPDLPEAS---ACPPGLL--------------------RASGSGPPYSNT 187

  Fly   190 LMRTQKEAISVMEKVISSQKDALRLVSHLIDYPGDALKIISKFMNSPFNALTVFTKFMSSPTDGV 254
            |.:|:.:..|.
  Rat   188 LAKTEVQGASC------------------------------------------------------ 198

  Fly   255 EIISKIVDSPADVVEFMQNLMHSPEDAIDIMNKFMNTPAEALRILNRILSGGGANAAQQTADRKP 319
                              :|.:|||
  Rat   199 ------------------HLEYSPE---------------------------------------- 205

  Fly   320 LLDKEPAVKPAAPAERADTVIQSMLGNSPPISPHDAAVDLQYHSPGVGEQPSTSSSHPLPYIANS 384
                      ...||..|::..:           |..:.|......:||....|.||..|...::
  Rat   206 ----------RGKAEGRDSIYST-----------DGQLTLGRRGLQLGEPEQGSDSHCSPSFCSA 249

  Fly   385 PDFDLKTFMQTNYNDEPSLDSDFSINSIESVLSEVIRIEYQAFNSIQQAASRVKEEMSYGTQSTY 449
            |                           |:..:.:..|||
  Rat   250 P---------------------------EAPYASLTDIEY------------------------- 262

  Fly   450 GGCNSAANNSQPHLQQPICAPSTQQLDRELNEAEQMKLRELRLASEALYDPVDEDLSALMMGDDR 514
                         |.|.:|        :...|..|::|.:|......|:.
  Rat   263 -------------LVQNVC--------KSYRETCQLRLEDLLRQRTNLFS--------------- 291

  Fly   515 IKPDDTRHNPKLLQLI------NLTAVAIKRLIKMAKKITAFRDMCQEDQVALLKGGCTEMMIMR 573
             :.:.|.:..|.:..:      :||. ||:.:::.||:::.|.::||.||:.|||.|..|::::|
  Rat   292 -REEVTSYQRKSMWEMWERCAHHLTE-AIQYVVEFAKRLSGFMELCQNDQIILLKAGAMEVVLVR 354

  Fly   574 SVMIYDDDRAAWKVPHT---KENMGNIR-------TDLLKFAEGNIYE-EHQKFITTFDEKWRMD 627
            ....|:.:.      ||   :...|.:.       ::|:    .:|:: .|......|.|    |
  Rat   355 MCRAYNANN------HTVFFEGKYGGVELFRALGCSELI----SSIFDFSHFLSALCFSE----D 405

  Fly   628 ENIILIMCAIVLFTSAR------SRVIHKDVIRLEQNSYYYLLRRYLESVYSGCEARNAFIKL-- 684
            |  |.:..|:||..:.|      .||.|.. ..||...:::|.:.:.:.:.:....:.....|
  Rat   406 E--IALYTALVLINANRPGLQEKRRVEHLQ-YNLELAFHHHLCKTHRQGLLAKLPPKGKLRSLCS 467

  Fly   685 --IQKISDVERLNKFIINVYLNVNPSQVEPLLREIF 718
              ::|:.|.:.|:..::.       :...||.:|:|
  Rat   468 QHVEKLQDFQHLHPIVVQ-------AAFPPLYKELF 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hr96	NP_524493.1	NR_DBD_CAR	5..98	CDD:143524	35/94 (37%)
		NR_LBD	462..>573	CDD:299703	26/116 (22%)
		NR_LBD_F1	523..702	CDD:132727	44/205 (21%)
Rorc	XP_006232988.2	NR_DBD_ROR	24..118	CDD:143526	35/91 (38%)
		NR_LBD_ROR_like	258..496	CDD:132737	59/324 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351549
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840