DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hr96 and Ppara

DIOPT Version :9

Sequence 1:	NP_524493.1	Gene:	Hr96 / 42993	FlyBaseID:	FBgn0015240	Length:	723	Species:	Drosophila melanogaster
Sequence 2:	XP_006242213.1	Gene:	Ppara / 25747	RGDID:	3369	Length:	605	Species:	Rattus norvegicus

Alignment Length:	318	Identity:	73/318 - (22%)
Similarity:	120/318 - (37%)	Gaps:	90/318 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 CAVCGDKALGYNFNAVTCESCKAFFRRNALAKKQF-TCPFNQNCDITVVTRRFCQKCRLRKCLDI 70
            |.:|||||.||::....||.||.||||....|..: .|  :::|.|....|..||.||..|||.:
  Rat   239 CRICGDKASGYHYGVHACEGCKGFFRRTIRLKLAYDKC--DRSCKIQKKNRNKCQYCRFHKCLSV 301

  Fly    71 GMKSENI------MSEEDKLIKRRKIETNRAKRRLMENGTDACDADGGEERDHKAPADSSSSN-- 127
            ||....|      .||:.||    |.|....:..|.::.|  .|.....:|.|:|...:.:.|
  Rat   302 GMSHNAIRFGRMPRSEKAKL----KAEILTCEHDLKDSET--ADLKSLAKRIHEAYLKNFNMNKV 360

  Fly   128 -----LDHYSGSQDSQSCGSADSGANGCSGRQASSPGTQVNPLQ---MTAEKIVDQIVSDPDRAS 184
                 |                      :|:.:::|...::.::   |..:.:|.::|::.....
  Rat   361 KARVIL----------------------AGKTSNNPPFVIHDMETLCMAEKTLVAKMVANGVENK 403

  Fly   185 QAINRLMRTQKEAISVMEKVISSQKDALRLVSHLIDYPGDALKIISKFMNSPFNALTVFTKFMSS 249
            :|..|...             ..|..::..|:.|.::    .|.|..|.|...|......|:
  Rat   404 EAEVRFFH-------------CCQCMSVETVTELTEF----AKAIPGFANLDLNDQVTLLKY--- 448

  Fly   250 PTDGV-----EIISKIVDSPADVV---------EFMQNLMHSP-----EDAIDIMNKF 288
               ||     .::|.:::....::         ||::|| ..|     |...|...||
  Rat   449 ---GVYEAIFTMLSSLMNKDGMLIAYGNGFITREFLKNL-RKPFCDIMEPKFDFAMKF 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hr96	NP_524493.1	NR_DBD_CAR	5..98	CDD:143524	37/97 (38%)
		NR_LBD	462..>573	CDD:299703
		NR_LBD_F1	523..702	CDD:132727
Ppara	XP_006242213.1	NR_DBD_Ppar	238..321	CDD:143523	33/83 (40%)
Ppara	XP_006242213.1	NR_LBD_PPAR	338..604	CDD:132730	34/211 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351552
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	3	2.890