DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hr96 and Rara

DIOPT Version :9

Sequence 1:	NP_524493.1	Gene:	Hr96 / 42993	FlyBaseID:	FBgn0015240	Length:	723	Species:	Drosophila melanogaster
Sequence 2:	XP_017452499.1	Gene:	Rara / 24705	RGDID:	3534	Length:	462	Species:	Rattus norvegicus

Alignment Length:	392	Identity:	93/392 - (23%)
Similarity:	154/392 - (39%)	Gaps:	102/392 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SPP------KNCAVCGDKALGYNFNAVTCESCKAFFRRNALAKKQFTCPFNQNCDITVVTRRFCQ 60
            |||      |.|.||.||:.||::....||.||.||||:......:||..::||.|..|||..||
  Rat    77 SPPPLPRIYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQ 141

  Fly    61 KCRLRKCLDIGMKSENIMSEEDKLIKRRKIETNRAKRRLMENGTDACDADGGE--ERDHKAPADS 123
            .|||:||.::||..|::.::.:|    :|.||  .|....|:.|  ...:.||  |:..||..::
  Rat   142 YCRLQKCFEVGMSKESVRNDRNK----KKKET--PKPECSESYT--LTPEVGELIEKVRKAHQET 198

  Fly   124 --SSSNLDHYSGSQDSQSCGSADSGANGCSGRQASSPGTQVNPLQMTAEKIVDQIVSDPDRASQA 186
              :...|..|:.:..|:...|.|                 ::.....:|.....|:...:.|.|.
  Rat   199 FPALCQLGKYTTNNSSEQRVSLD-----------------IDLWDKFSELSTKCIIKTVEFAKQL 246

  Fly   187 INRLMRTQKEAISVMEKV------------ISSQKDALRLVSHLIDYPGDALKI-ISKFMNSPFN 238
            ......|..:.|::::..            .:.::|.:..        .|.|.: .::..|:.|.
  Rat   247 PGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTF--------SDGLTLNRTQMHNAGFG 303

  Fly   239 ALT--VF---TKFMSSPTDGVE--IISKIVDSPADVVEFMQNLMHSPEDAIDIMNKFMNTPAEAL 296
            .||  ||   .:.:....|..|  ::|.|.....|..:..|      .|.:|::.:.:   .|||
  Rat   304 PLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQ------PDKVDMLQEPL---LEAL 359

  Fly   297 RILNRILSGGGANAAQQTADRKPLLDKEPAVKP-------------AAPAERADTVIQSMLGNSP 348
            ::..|              .|:|   ..|.:.|             |..|||..|:...:.|:.|
  Rat   360 KVYVR--------------KRRP---SRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPGSMP 407

  Fly   349 PI 350
            |:
  Rat   408 PL 409

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hr96	NP_524493.1	NR_DBD_CAR	5..98	CDD:143524	39/92 (42%)
		NR_LBD	462..>573	CDD:299703
		NR_LBD_F1	523..702	CDD:132727
Rara	XP_017452499.1	NR_DBD_RAR	82..166	CDD:143522	35/87 (40%)
Rara	XP_017452499.1	NR_LBD_RAR	186..416	CDD:132735	48/275 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351555
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930