DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hr96 and Rarg

DIOPT Version :9

Sequence 1:	NP_524493.1	Gene:	Hr96 / 42993	FlyBaseID:	FBgn0015240	Length:	723	Species:	Drosophila melanogaster
Sequence 2:	NP_035374.3	Gene:	Rarg / 19411	MGIID:	97858	Length:	458	Species:	Mus musculus

Alignment Length:	109	Identity:	41/109 - (37%)
Similarity:	59/109 - (54%)	Gaps:	17/109 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SPP------KNCAVCGDKALGYNFNAVTCESCKAFFRRNALAKKQFTCPFNQNCDITVVTRRFCQ 60
            |||      |.|.||.||:.||::...:||.||.||||:......:||..::||.|..|||..||
Mouse    79 SPPPPPRVYKPCFVCNDKSSGYHYGVSSCEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQ 143

  Fly    61 KCRLRKCLDIGMKSENIMSEEDKLIKRRKIETNRAKRRLMENGT 104
            .|||:||.::||..|.:.::.           |:.|:.:.|.|:
Mouse   144 YCRLQKCFEVGMSKEAVRNDR-----------NKKKKEVKEEGS 176

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hr96	NP_524493.1	NR_DBD_CAR	5..98	CDD:143524	36/92 (39%)
		NR_LBD	462..>573	CDD:299703
		NR_LBD_F1	523..702	CDD:132727
Rarg	NP_035374.3	Modulating	1..89		3/9 (33%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	58..83		3/3 (100%)
		NR_DBD_RAR	85..165	CDD:143522	34/90 (38%)
		Hinge	156..184		5/32 (16%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	161..180		4/27 (15%)
		NR_LBD_RAR	188..418	CDD:132735
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	409..458
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847961
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930