DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hr96 and nhr-242

DIOPT Version :9

Sequence 1:	NP_524493.1	Gene:	Hr96 / 42993	FlyBaseID:	FBgn0015240	Length:	723	Species:	Drosophila melanogaster
Sequence 2:	NP_001343692.1	Gene:	nhr-242 / 190547	WormBaseID:	WBGene00022097	Length:	305	Species:	Caenorhabditis elegans

Alignment Length:	290	Identity:	79/290 - (27%)
Similarity:	122/290 - (42%)	Gaps:	26/290 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 CAVCGDKALGYNFNAVTCESCKAFFRRNALAKKQFTCPFNQNCDITVVTRRFCQKCRLRKCLDIG 71
            |||||.||....:.|::|..|..||||....:|::.|..|:||:|.:.||..|:.|||:|||::|
Worm    21 CAVCGGKASSSRYGALSCIGCLVFFRRMTCGEKKWYCLRNRNCEINIATRNTCRACRLQKCLNVG 85

  Fly    72 MKSENIMSEEDKLIKRRKIETNRAKRRLMENGTDA----CDADGGEERDHKAPADSSSSNLDHYS 132
            |....|...::  |..||.:.::..::.....|.:    |...|.:.....|....|.|.|.|..
Worm    86 MNPNAIQRRDE--IGPRKPKVSKFSQKQYNAATSSECAMCLHIGFQNALEWANQLESFSMLSHVD 148

  Fly   133 GSQDSQSCGSA----DSGANGCSGRQASSPGTQVNPLQMTAEKIVDQIV--SDPDRASQAINRLM 191
            ........|.|    |.|.     :.|.....|...||..:....:|:.  ||.|..:|.|..:.
Worm   149 KQNILSEYGIAFTLIDQGY-----KTARDADEQCWLLQNGSVLHCEQLFNSSDADLVNQLIANIS 208

  Fly   192 RTQKEAISVMEKVISSQKDALRLVSHLIDYPGDALKIISKFMNSPFNALTVFTKFMSSPTDGVEI 256
            :..|. :.:.|......|..|.|.|   .:||: :::.|:  .|....||...:..:.|....||
Worm   209 QPLKR-LELDEYECGLLKSLLLLSS---SFPGE-VQLNSQ--QSRAKCLTEMLQHRNDPERFGEI 266

  Fly   257 ISKIVDSPADVVEFMQNLMHSPEDAIDIMN 286
            |..|....:.|..|......|  |..:::|
Worm   267 ILLIGSIRSSVKLFYNQTKRS--DLFNVLN 294

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hr96	NP_524493.1	NR_DBD_CAR	5..98	CDD:143524	35/90 (39%)
		NR_LBD	462..>573	CDD:299703
		NR_LBD_F1	523..702	CDD:132727
nhr-242	NP_001343692.1	NR_DBD_HNF4A	21..96	CDD:143518	32/74 (43%)
nhr-242	NP_001343692.1	Hormone_recep	105..289	CDD:306586	42/197 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D153746at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010