Protein Alignment Hr96 and vdr

DIOPT Version :10

• Sequence 1: NP_524493.1
• Gene: Hr96 / 42993
• FlyBaseID: FBgn0015240
• Length: 723
• Species: Drosophila melanogaster
• Sequence 2: XP_002935703.1
• Gene: vdr / 100491661
• XenbaseID: XB-GENE-486505
• Length: 420
• Species: Xenopus tropicalis
• Alignment Length: 738
• Identity: 137/738 - (18%)
• Similarity: 217/738 - (29%)
• Gaps: 366/738 - (49%)

  Fly     4 PKNCAVCGDKALGYNFNAVTCESCKAFFRRNALAKKQFTCPFNQNCDITVVTRRFCQKCRLRKCL 68
            |:.|.||||||.|::|||:|||.||.||||:...|..||||||.:|.||...||.||.|||::|:
 Frog    21 PRICGVCGDKATGFHFNAMTCEGCKGFFRRSMKRKAVFTCPFNGDCRITKDNRRHCQSCRLKRCV 85

  Fly    69 DIGMKSENIMSEEDKLIKRRKIETNRAKRRLMENGTDACDADGGEERDHKAPADSSSSNLDHYSG 133
            ||||..|.|:::|:...||..|...:.:..|.|:
 Frog    86 DIGMMKEFILTDEEVQRKREMITKRKEEEALKES------------------------------- 119

  Fly   134 SQDSQSCGSADSGANGCSGRQASSPGTQVNPLQMTAE--KIVDQIVSDPDRASQAINRLMRTQKE 196
                                        :.| :|:.|  |::|.:|
 Frog   120 ----------------------------MRP-KMSEEQQKMIDVLV------------------- 136

  Fly   197 AISVMEKVISSQKDALRLVSHLIDYPGDALKIISKFMNSPFNALTVFTKFMSSPTDGVEIISKIV 261
                         ||.|                 |..::.::....|     .|.....:..:|.
 Frog   137 -------------DAHR-----------------KTFDTTYSDFGQF-----RPPVRENVCKRIT 166

  Fly   262 DSPADVVEFMQNLMHSPEDAIDIMNKFMNTPAEALRILNRILSGGGANAAQQTADRKPLLDKEPA 326
            .|                                    :.||:.|
 Frog   167 RS------------------------------------SSILTQG-------------------- 175

  Fly   327 VKPAAPAERADTVIQSMLGNSPPISPHDAAVDLQYHSPGVGEQPSTSSSHPLPYIANSPDFDLKT 391
                                                          |||.......:|||.....
 Frog   176 ----------------------------------------------SSSEDSDVFTSSPDCSEHG 194

  Fly   392 FMQTNYNDEPSLDSDFSINSIESVLSEVIRIEYQAFNSIQQAASRVKEEMSYGTQSTYGGCNSAA 456
            |....     ||...|..:|::....::..:
 Frog   195 FFSAG-----SLFGHFEHSSMDGKAGDLSML---------------------------------- 220

  Fly   457 NNSQPHLQQPICAPSTQQLDRELNEAEQMKLRELRLASEALYDPVDEDLSALMMGDDRIKPDDTR 521
                ||
 Frog   221 ----PH----------------------------------------------------------- 222

  Fly   522 HNPKLLQLINLTAVAIKRLIKMAKKITAFRDMCQEDQVALLKGGCTEMMIMRSVMIYDDDRAAW- 585
                   |.:|.:.:|:::|..||.|..|||:..|||:||||....|::::||...:..|..:|
 Frog   223 -------LADLVSYSIQKVIGFAKMIPGFRDLIAEDQIALLKSSVIEVIMLRSNQSFSLDDMSWT 280

  Fly   586 -----------KVPHTKENMGNIRTDLLKFAEG----NIYEEHQKFITTFDEKWRMDENIILIMC 635
                       .|.....|| .:...|:||..|    |::||               |:::|:
 Frog   281 CGSEDFKYKVDDVTQAGHNM-ELLEPLVKFQVGLKKLNLHEE---------------EHVLLM-- 327

  Fly   636 AIVLFTSARSRVIHKDVIRLEQNSYYYLLRRYLESVYSGCEARNAFIKLIQKISDVERLNKFIIN 700
            ||.:.:..|..|..|.::...|:.....|:.|:...:....:|..:.|:|||::|:..||:....
 Frog   328 AICILSPDRPGVQDKALVESIQDRLSATLQTYILCKHPPPGSRLLYAKMIQKLADLRSLNEEHSK 392

  Fly   701 VYLNV-----NPSQVEPLLREIF 718
            .|.::     :..|:.||:.|:|
 Frog   393 QYRSISFLPEHSMQLTPLVLEVF 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hr96	NP_524493.1	NR_DBD_CAR	5..98	CDD:143524	48/92 (52%)
		NR_LBD	462..>573	CDD:472173	19/110 (17%)
		NR_LBD_F1	523..702	CDD:132727	50/194 (26%)
vdr	XP_002935703.1	NR_DBD_VDR	16..122	CDD:143513	51/159 (32%)
		NR_LBD_VDR	124..419	CDD:132731	85/575 (15%)