Protein Alignment Hr96 and nr1d2

DIOPT Version :9

• Sequence 1: NP_524493.1
• Gene: Hr96 / 42993
• FlyBaseID: FBgn0015240
• Length: 723
• Species: Drosophila melanogaster
• Sequence 2: NP_001361696.1
• Gene: nr1d2 / 100101761
• XenbaseID: XB-GENE-478410
• Length: 601
• Species: Xenopus tropicalis
• Alignment Length: 720
• Identity: 135/720 - (18%)
• Similarity: 232/720 - (32%)
• Gaps: 280/720 - (38%)

  Fly     7 CAVCGDKALGYNFNAVTCESCKAFFRRNALAKKQF-TCPFNQNCDITVVTRRFCQKCRLRKCLDI 70
            |.||||.|.|:::....||.||.||||:.....|: .|..|::|.|..:.|..||:||.:|||.:
 Frog   117 CKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKKCLKNESCSIIRINRNRCQQCRFKKCLSV 181

  Fly    71 GMKSENIMSEEDKLIKRRKIETNRAKRRLMENGTDACDADGGEERDHKAPADSSSSNLDHYSGSQ 135
            ||..:.:  ...::.||.|      :|.|:|
 Frog   182 GMSRDAV--RFGRIPKREK------QRMLIE---------------------------------- 204

  Fly   136 DSQSCGSADSGANGCSGRQASSPGTQVNPLQMTAEKIVDQIVSDPDRASQAINRLMRTQKEAISV 200
                                                                   |:|      |
 Frog   205 -------------------------------------------------------MQT------V 208

  Fly   201 MEKVISSQKDALRLVSHLIDYPGDALKIISKFMNSPFNALTVFTKFMSSPTDGVEIISKIVDSPA 265
            |:.::|:|.....|...|.||                                        .:|:
 Frog   209 MKTMMSNQFSGSSLQETLPDY----------------------------------------QAPS 233

  Fly   266 DVVEFMQNLMHSPEDAIDIMNKFMNTPAEALRILNRILSGGGANAAQQTADRKPLLDKEPAVKPA 330
            .        :..|..|::.|                      |:..|..::.|.|   .|.:.|:
 Frog   234 S--------LQLPHTALEKM----------------------ASKTQHYSENKAL---TPPLPPS 265

  Fly   331 APAERADTVIQSMLGNSPPISPHDAAVDLQYHSPGVGEQPSTSSSHPLPYIANSPDFDLKTFMQT 395
            .|             :.||:...|.:.:     ..:|   :.:.:|            .:|||
 Frog   266 LP-------------HPPPVMSMDISKE-----DVIG---TVTGAH------------RETFM-- 295

  Fly   396 NYNDEPSLDSDFSINSIESVLSEVI-RIEYQAFNSIQQAASRVKEEMSYGTQSTYGGCNSAAN-- 457
             ||..|......:....|.:.|.|. |......|.|..|...|.:...|        .|.|.|
 Frog   296 -YNQVPVEFPSEAGRQQEEIHSNVTHRNNDHMRNGIIAAHCPVNKSKQY--------LNEADNDR 351

  Fly   458 NSQPHLQQPI-CAPSTQQLDR-------------ELNEAEQMKL----RELRLASEALYDPVDED 504
            |...:...|: |..:.|.:..             :::....:.|    |.:.|.......|.
 Frog   352 NFMHYPNGPVNCFSNGQNISSGWSHRGCISEKMLDVSHVNSVNLCNRGRRMHLVCPMSMTPF--- 413

  Fly   505 LSALMMGDDRIKPDDTRHNPKLLQLINLT-AVAIKRLIKMAKKITAFRDMCQEDQVALLKGGCTE 568
                        .|..:...::.:..::: ..|:|.::..||.|..|:|:.|.|||.|||.|..|
 Frog   414 ------------MDPNKSGTQIWEEFSMSFTPAVKEVVDFAKGIPGFKDLSQHDQVNLLKAGTFE 466

  Fly   569 MMIMRSVMIYD-DDRAAWKVPHTKENMGNIRT----DLLKFAEGNIYEEHQKFITTFDEK---WR 625
            ::::|...::| .:|....:...|.::..:|.    |||    .:::|        |.||   .:
 Frog   467 VLMVRFASLFDAKERTVTFLSGKKYSVDELRLMGAGDLL----NSVFE--------FSEKLSALQ 519

  Fly   626 MDENIILIMCAIVLFTSARSRVIHKDVIRLEQNSYYYLLRRYLESVYSGCEARNAFIKLIQKISD 690
            :.|..:.:..|:||.::.||.:.:.:.:...|.:....||..:...:.. || :.|.||:.|:.|
 Frog   520 LSEEEMSLFTAVVLVSADRSGIENVNSVEALQETLLRALRTLIMRNHQN-EA-STFTKLLLKLPD 582

  Fly   691 VERLN 695
            :..||
 Frog   583 LRSLN 587

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hr96	NP_524493.1	NR_DBD_CAR	5..98	CDD:143524	33/91 (36%)
		NR_LBD	462..>573	CDD:299703	24/129 (19%)
		NR_LBD_F1	523..702	CDD:132727	46/182 (25%)
nr1d2	NP_001361696.1	NR_DBD_REV_ERB	112..200	CDD:143540	33/90 (37%)
		NR_LBD_REV_ERB	412..599	CDD:132738	48/205 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000