DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hr96 and rargb

DIOPT Version :9

Sequence 1:	NP_524493.1	Gene:	Hr96 / 42993	FlyBaseID:	FBgn0015240	Length:	723	Species:	Drosophila melanogaster
Sequence 2:	NP_001076779.1	Gene:	rargb / 100034753	ZFINID:	ZDB-GENE-070314-1	Length:	489	Species:	Danio rerio

Alignment Length:	375	Identity:	83/375 - (22%)
Similarity:	130/375 - (34%)	Gaps:	124/375 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SPP------KNCAVCGDKALGYNFNAVTCESCKAFFRRNALAKKQFTCPFNQNCDITVVTRRFCQ 60
            |||      |.|.||.||:.||::...:||.||.||||:......:||..::||.|..|||..||
Zfish    54 SPPPPPRVYKPCFVCQDKSSGYHYGVSSCEGCKGFFRRSIQKNMVYTCHRDKNCQINKVTRNRCQ 118

  Fly    61 KCRLRKCLDIGMKSENIMSEEDKLIKRRKIE----------------TNRAKRRLMENGTDACDA 109
            .||||||.::||..|.:.::.:|..|..|.|                .|:..:...|.....|..
Zfish   119 YCRLRKCFEVGMSKEAVRNDRNKKKKDVKEEVVLPESYELSGELEELVNKVSKAHRETFPSLCQL 183

  Fly   110 ---DGGEERDHKAPAD---------------------------------------SSSSNLD--- 129
               ......||:...|                                       ..|:.||
Zfish   184 GKYTTNSSADHRVQLDLGLWDKFSELSTKCIIKIVEFAKRLPGFTSLTIADQITLLKSACLDILM 248

  Fly   130 -----HYSGSQDSQSCGSA---------DSGANGCSGRQASSPGTQVNPLQM--TAEKIVDQI-- 176
                 .|:..||:.:....         ::|....:....:..| |:.||:|  |...::..|
Zfish   249 LRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFAFAG-QLLPLEMDDTETGLLSAICL 312

  Fly   177 -------VSDPDRASQAINRLMRTQKEAISV----------------MEKVIS----SQKDALRL 214
                   :.:|.|..|....|:    ||:.:                :.||..    |.|.|.|.
Zfish   313 ICGDRMDLEEPHRVDQLQEPLL----EALKIYARRRRPNKPHMFPRMLMKVTDLRGISTKGAERA 373

  Fly   215 VSHLIDYPGDALKIISKFMNSPFNALTVFTKFMSSPTDGVEIISKIVDSP 264
            ::..::.||....:|.:.:.:|    .:|.....|...|.   :.:|.:|
Zfish   374 ITLKMEIPGPMPPLIREMLENP----EIFEDSSDSNDSGA---AAVVPAP 416

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hr96	NP_524493.1	NR_DBD_CAR	5..98	CDD:143524	40/108 (37%)
		NR_LBD	462..>573	CDD:299703
		NR_LBD_F1	523..702	CDD:132727
rargb	NP_001076779.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	37..57		2/2 (100%)
		NR_DBD_RAR	60..140	CDD:143522	35/79 (44%)
		NR_LBD_RAR	164..394	CDD:132735	35/234 (15%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	398..489		5/22 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593335
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930