DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment beta4GalT7 and sqv-3

DIOPT Version :9

Sequence 1:	NP_651319.2	Gene:	beta4GalT7 / 42991	FlyBaseID:	FBgn0039258	Length:	322	Species:	Drosophila melanogaster
Sequence 2:	NP_499164.1	Gene:	sqv-3 / 176382	WormBaseID:	WBGene00005021	Length:	289	Species:	Caenorhabditis elegans

Alignment Length:	253	Identity:	124/253 - (49%)
Similarity:	172/253 - (67%)	Gaps:	9/253 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 DEKQPQPHDHGASVHKMALLVPFRDRFEELLQFVPHMTAFLKRQGVAHHIFVLNQVDRFRFNRAS 125
            |...|:|..  .|.||:.::||:|||.|||.:|.|||:.||..|.|:|||.::||.|..||||||
Worm    39 DYVDPRPLQ--TSYHKLCVIVPYRDRLEELREFSPHMSKFLHNQNVSHHILIINQTDPLRFNRAS 101

  Fly   126 LINVGFQFASDV-YDYIAMHDVDLLPLNDNLLYEYPSSLGPL-HIAGPKLHPKYHYDNFVGGILL 188
            |||||:..|..: .||:.|:||||||:|..:.|::| .:|.: ||..|:.||||||:.|:||||:
Worm   102 LINVGWNEADRLGCDYMVMNDVDLLPVNPEVPYDFP-GIGVIRHITSPQYHPKYHYEKFIGGILM 165

  Fly   189 VRREHFKQMNGMSNQYWGWGLEDDEFFVRIRDAGLQVTRPQNIKTGTNDTFSHIHNRYHRKRD-- 251
            :..:.:|::|||||:|||||||||||::||.|:.|.:||...:.|.:::||.|||.. .||||
Worm   166 LTLKDYKKLNGMSNKYWGWGLEDDEFYLRIIDSKLNLTRVSGLSTDSSNTFRHIHGP-KRKRDYT 229

  Fly   252 -TQKCFNQKEMTRKRDHKTGLDNVKYKILKVHEMLIDQVPVTILNILLDCDVNKTPWC 308
             .:...||.|:.|||||.:||.:|:|.|.....:......|||:|:.|.||:|.||:|
Worm   230 PKKNDKNQWEIKRKRDHVSGLHDVRYLIDSRQLLDFSGTSVTIINVALHCDLNWTPYC 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
beta4GalT7	NP_651319.2	b4GalT	75..299	CDD:132999	113/228 (50%)
sqv-3	NP_499164.1	b4GalT	50..278	CDD:132999	113/229 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167341
Domainoid	1	1.000	104	1.000	Domainoid score	I4240
eggNOG	1	0.900	-	-		E1_KOG3917
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5248
Inparanoid	1	1.050	246	1.000	Inparanoid score	I2044
Isobase	1	0.950	-	0	Normalized mean entropy	S3314
OMA	1	1.010	-	-		QHG48176
OrthoDB	1	1.010	-	-		D1201618at2759
OrthoFinder	1	1.000	-	-		FOG0008371
OrthoInspector	1	1.000	-	-		oto19725
orthoMCL	1	0.900	-	-		OOG6_106739
Panther	1	1.100	-	-	LDO	PTHR19300
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2814
SonicParanoid	1	1.000	-	-		X6358
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	18	17.750