Protein Alignment tnc and CG1647

DIOPT Version :10

• Sequence 1: NP_651318.3
• Gene: tnc / 42990
• FlyBaseID: FBgn0039257
• Length: 2819
• Species: Drosophila melanogaster
• Sequence 2: NP_651636.1
• Gene: CG1647 / 43401
• FlyBaseID: FBgn0039602
• Length: 1222
• Species: Drosophila melanogaster
• Alignment Length: 1411
• Identity: 280/1411 - (19%)
• Similarity: 486/1411 - (34%)
• Gaps: 369/1411 - (26%)

  Fly  1271 SEEDSKPIDESEEDKKPVE-----ESAEDKKPVEDSEEKEKPLPTVIPASEIEKESKPEDEKKTE 1330
            :|||:..:||....:|..|     .|.:||            :|..|.:..::|.:
  Fly    37 NEEDTIDLDEPRMSQKIYELVGFTVSVDDK------------MPQTICSQCVDKIN--------- 80

  Fly  1331 ADFAAPTEQPEATTPAQIADTAEKEVDDKLATTSAPVSGEDELKPADEKKRTETAQIPDAEIPAS 1395
             ||....|...||         .|:..:.|..                 |:.|.|::.|.:....
  Fly    81 -DFYEFREMCYAT---------NKQTRNLLGL-----------------KQIEPARLIDLKRIVK 118

  Fly  1396 TDEPESSTELPTVDLDKKPEEDSTKGTEA-PESDKV-PEVPTSASTENEIEESDKFTTVAPPKI- 1457
            .:.|.|..      :.|:..:  .||.|: |:::.| |:|...:...::.::      :.|.:|
  Fly   119 EERPISGA------VGKRGRK--RKGEESWPKNNNVKPQVKKESFVWHKKQK------LQPSQIT 169

  Fly  1458 SASDETEPTAEEDLVPATFEPIESEFEVSTKKPAVQGPPLPTLAPAQPEKK-------PVDAETS 1515
            |...:.||..::       ||.|.:       .:::|||          ||       .|..|..
  Fly   170 SLVSKREPEIKD-------EPAEQD-------TSLKGPP----------KKAGRKSICSVCGEKF 210

  Fly  1516 TEADISTEPSAEVEK--------EASGETSESDNEIDA-----GASSTPVPVSADEDKTPSTEKT 1567
            ...:::.|..:.|..        .|..:|..:.::|.|     ..|.||.       |.|..|.:
  Fly   211 LSKELADEHKSLVHVPSIPRYICNACNQTHHNQSDIRAHQLWHKLSKTPY-------KCPLCESS 268

  Fly  1568 VEADDKFTTVAPLAGDEEESNLPKLPQD--IFEEEAPVAVTTAAPS-------------KDDGEQ 1617
            |.....||.       ....:.|..|..  :.:.|.|:...|...:             |..|..
  Fly   269 VANAYAFTR-------HLREHTPPTPVQLLVLDRECPLCKKTFVTNFFYNTHRCAIRKRKCGGCS 326

  Fly  1618 KPVEVE----------EKPIEDGQKPIEDETSTPTSS---ENEIEPE---SDRATTIAPS--KEE 1664
            :.:..|          .|...:..|.|..:..|..:.   :||||.|   ...|||:.|.  .:|
  Fly   327 RTLNTEAAYMRHAPTCPKIYLNHSKHIMPQVVTNEAQMLIKNEIEEELLGLPPATTVPPDFVIDE 391

  Fly  1665 PSEPSTGAPTKDEP---AEPSTDAPESDESKETPESEVPTTVAPAGEKIPTSSIT-------PDE 1719
            ..:|.........|   :...||...:.:||.:........:....:.:..:..|       |:.
  Fly   392 GMQPVVVLERLSSPLLRSSSGTDQLVAAKSKNSDRVSARNYLKRVDQLLKNTINTLVSIKHEPEV 456

  Fly  1720 EPTATSAPVAKPDEDVEKETSTEIPTDAPASSEEDENSSTDQIPSEVPEKKPETPAQTPEEGDIV 1784
            ....|..|..:.:.|.|.|.:.|.|     |..:|..::.|    |..|.:|||      |.|.:
  Fly   457 HINDTGPPRGQAESDPEPERNEEHP-----SFGDDIQAAND----ECQECQPET------ESDKI 506

  Fly  1785 GATAAPTTSDEVPPVQRLPEEVLAEIPQPSTETGIKQQDETTAAPSIDRKEP------------- 1836
            ...|.    |::|.|....|   .|......:||:||             ||
  Fly   507 SVAAC----DDIPSVSVKQE---PEYDGYEKQTGVKQ-------------EPLKLKLKITKNHGK 551

  Fly  1837 ----YVTEIDEEATTVAPISEKDEKPTEEEKPVEQKPTGEEPSEEEEKEKPIEQDVSTEGPVSTE 1897
                .:.::||........|:|.:|                     .|.|..|::.|.|
  Fly   552 LNSSLIDDLDEAGQAFGRSSKKKKK---------------------RKHKEREKEASNE------ 589

  Fly  1898 ASEAGSTESSEEVKPSTEGEVAEKPEDKQPSSTAQAPVETIP--EISTELPAQDGDKPTSEAPVD 1960
             :|...|||..:  |:.  ::.::|.|..|.:|.   :.|||  :..:.|...:..:...||.:.
  Fly   590 -TENCRTESQNQ--PAI--KIKQEPVDYAPEATV---MTTIPMTQFESSLNESERSEEVDEAMIQ 646

  Fly  1961 SDEDTSAPSDE-----KIPSV-SGEEV-EGPEVTTASPQAAEEDEL---KTPAESEPSSTDKVPE 2015
            |.||......|     :|.:| ||.:: |.......:.:|..||.|   |:...:...||.....
  Fly   647 SQEDVKPNRMELDRMMQISNVTSGVDMAEEAMALERAEEACPEDSLHKVKSVKSTARKSTGGAER 711

  Fly  2016 TEYQKPEDETKADETPESVTQVSDVATSTSAPV-------AGGDIEKDEQATTASP-------EE 2066
            ..|..|...|    .|:.|..||..:......:       ..||.|.::|..|...       ||
  Fly   712 KTYSPPRTNT----LPQIVAVVSGESAFNMISIKPEPRNLGYGDEEPEDQRETTEEINHNDMMEE 772

  Fly  2067 EEEIKPTIAPAAEIPQPSEKEPVDEQEVE----SGTKATPAESDGQPIDEIAPATSGPIDEASTA 2127
            |:|...:: ..:::....|:| :|..|::    :|.:.:..:.|....|..:.|     |||..|
  Fly   773 EKEYIGSL-DLSDVSVKQERE-LDICEIDAVHRNGLEKSDEDDDDGNEDSASSA-----DEAEEA 830

  Fly  2128 APTKEESTTVASAASPAVHDDEIKDVTTTQPVADEKEVAAPQDETKTSIDVSTDSPTAQDD---- 2188
            .....|.........|.:   |:::.::.:.:..|:    ...|..|::..| ::|:...|
  Fly   831 MERDTEERIYREIELPPL---ELQNESSRKDLESER----MDTEVSTALPAS-ETPSQTRDVLGV 887

  Fly  2189 EKQDKTEAPVAPTTVSSPTADSAADSSTPTVEV---PSPVEIDTKPMDDIMSQTIAP--HTADGA 2248
            ||.:.:...:..|.:.|......:.:.:..:|.   |||            |.|..|  ||.:..
  Fly   888 EKSEASAFSLVITNICSQAVPQPSAACSNDIECSIGPSP------------STTNEPHSHTVENV 940

  Fly  2249 ASTSTEDEDQAPVTVSPQDAEKTPVSPAPQDSDKTPSSEAPQDADEIPATATPL---DDNKIPAT 2310
            .|.:.:.:..|.|.::.|......:...|     ..|||:..|..::|..|:.:   :...:|..
  Fly   941 QSPANDLQTSAQVAIAAQSQPDPCIVSQP-----AASSESQADTKDLPPAASQIQTFNTESLPIH 1000

  Fly  2311 VAPQTDDGVPATAAPLDEDKIQTTAAPLDEEKIPSTAAPLDDEKIPAP--VSPVVFDVEPSSEKP 2373
            |..:|:|......|...|.:.|........|. ||.... .:|.:|:.  |||:     |.:..|
  Fly  1001 VHSETEDNSIENDASYLESRAQVDCQSAGTEN-PSVVLE-QNESLPSGSCVSPI-----PENPSP 1058

  Fly  2374 AVSEYDGEESTEPPVHDVETSTDEPTSDAKLKPPTSAPATPS-ESPA-TEAEIVPETAAPELEKE 2436
            ..|         ||.||...|.|:|...|   ......||.| ::|. |||..:|...|..::..
  Fly  1059 GNS---------PPQHDESESLDKPEMAA---GSAYCLATVSLDAPKDTEALALPPCDAAIIDSN 1111

  Fly  2437 VPEKATEQPELEKETPEKATEQPELEKETPEKATEQPELEKETPEKATEQPELEKEVTDKATEQP 2501
            ......:|..|..|..|:  :...:|........|||.|.:..|...:.:|..|.|  ::..||.
  Fly  1112 YTSDEEQQNVLNHELSEQ--QLAIMEHRQLLVHEEQPALLEVIPPGLSSRPIEETE--NRINEQQ 1172

  Fly  2502 ESVDEKTTPEPVVKPSLDSTEEDEESVESEEESADKKDKNKETEED 2547
            :.:::.....|..:.:      |:.::....|:.:..:..:|.::|
  Fly  1173 QDLEQGEERPPRFQAN------DDSNINEIAENNNNANIERELQDD 1212

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tnc	NP_651318.3	VWC	47..105	CDD:450195
		VWC	235..296	CDD:214564
		LGT	<469..641	CDD:469786
		MDN1	484..1426	CDD:444083	30/160 (19%)
		PRK12323	<1240..1648	CDD:481241	77/432 (18%)
		MDN1	1523..2549	CDD:444083	231/1144 (20%)
		VWC	2762..>2805	CDD:450195
CG1647	NP_651636.1	zf-AD	19..95	CDD:214871	18/88 (20%)
		C2H2 Zn finger	203..224	CDD:275368	3/20 (15%)
		C2H2 Zn finger	233..253	CDD:275368	4/19 (21%)
		C2H2 Zn finger	262..282	CDD:275368	5/26 (19%)
		C2H2 Zn finger	297..314	CDD:275368	2/16 (13%)