Protein Alignment tnc and leo1

DIOPT Version :9

• Sequence 1: NP_001247300.1
• Gene: tnc / 42990
• FlyBaseID: FBgn0039257
• Length: 2819
• Species: Drosophila melanogaster
• Sequence 2: NP_996950.1
• Gene: leo1 / 404599
• ZFINID: ZDB-GENE-040426-2435
• Length: 696
• Species: Danio rerio
• Alignment Length: 830
• Identity: 169/830 - (20%)
• Similarity: 292/830 - (35%)
• Gaps: 229/830 - (27%)

  Fly   484 TEEDVKPTTAGTISEEEEEGKPTPAEEGSGEEEKDVKVTAAPEETEDEAKPTSAPVASDEKEQEP 548
            ::.:.:.:.:|:.|:.:.| :|..|...||.|..........:|.||..||::..:..|:.|.|
Zfish    14 SDNEQRDSGSGSGSDSDHE-RPRSASNASGSESAQSDRDHDDDEDEDGGKPSNKELFGDDSEDE- 76

  Fly   549 KPSEGSGDEELDLKPTTAPTAGAT------SASEESEEQDE--GKSTEAPTSVDDIEPAKPTESS 605
            ..|:.||.:....:.:.:..:|:.      |.|:.|..|.|  |..::|....|:..........
Zfish    77 HGSQHSGSQHSGSRHSGSRHSGSRHSGSRHSGSQHSGSQSERSGNQSDATMHSDNEHSMSEAHRG 141

  Fly   606 EEASGEGEDVAKETTPAGEASIAGEEEIVKGTTPAGEPSSEGDEEIVKGTTPAEESSSESEDELT 670
            |:...:.:|....:.....||.||.....:|   :|.|.||..       :|..|:.|...|
Zfish   142 EQDDEDDDDRGHRSDVGSPASGAGSRRSDRG---SGSPGSEAG-------SPRSEAGSGHSD--- 193

  Fly   671 KVTTPAGEPSVAGEEEIAKETTPAGEPSIAGEEEIVKVTTPAGESSIAGEEEIVKVTTPAGESSS 735
                 .|.|...||        .:|:.:.:|:|:    ....|:|..:.:|:        .:.:|
Zfish   194 -----PGTPHTDGE--------GSGKDAHSGDEK----WGGDGKSDQSEDED--------KQQNS 233

  Fly   736 EGEEEIIKVTTPAGESSSEGDEEIVKESTPAGEPISEGEEDVIK------ATTSAPKSDIE--GV 792
            :.|.|         .|..||:.:  |..:..|   |:.|:|..:      |:.|...||.|  |.
Zfish   234 DDERE---------RSDEEGERQ--KSESIKG---SDSEDDFTRKKKKKIASDSDSDSDAETQGG 284

  Fly   793 KEPET------ATEVPAEEVEDFAKPTTPIAEAEEEPIAGTPIPT-DGISGEEEIVKGTTPQTLE 850
            |:|..      |.::.::  .|..||.||          |.|:.. ||:.|::       |:. |
Zfish   285 KKPAANDLFGEADDISSD--SDAEKPLTP----------GQPLDADDGMEGDQ-------PEE-E 329

  Fly   851 EQPEISEESTEVPVAEDDLSSSTSASAIASSTEGVQDAASETTSSAPARAGD----KDEAATTVP 911
            ..||...| .|:|....||.|......:.:..            |...|..|    :||.
Zfish   330 PAPETRIE-VEIPKVSTDLGSDLYFVKLPNFL------------SVEPRPFDPQYYEDEF----- 376

  Fly   912 TAQDKDDEEV--EQDAT--DLPVEDVVQSTTAKTTTTEQPKEESSTEAEDAEIEVTTSSPADKQE 972
                 :|||:  |:..|  .|.||:.::..:.:.....:.||.::...:.::..::.....:..:
Zfish   377 -----EDEEMLDEEGRTRLKLKVENTIRWRSRRDEEGNEVKESNARIVKWSDGSMSLHLGNEVFD 436

  Fly   973 VPEAEPADKDHKDEEDVQTATDLPIKSDIGPPVVDTEATTGQPETSDETATDKPPSVYLPPGGEK 1037
            |.:| |...|| :...::..|.|.     |..|..|:.|. :|.::| :||.:..::.|
Zfish   437 VYKA-PLQGDH-NHLFIRQGTGLQ-----GQAVFKTKLTF-RPHSTD-SATHRKMTLSL------ 486

  Fly  1038 DTEKEDETTATEPSVQEEPSKPVDISPVSQEVPSSTAKVDNRND-FETEKPTLPPSGEDQSS--- 1098
                .|..:.|:         .:.|.|::...|.|     .||: .:.|:..|..|...:|.
Zfish   487 ----ADRCSKTQ---------KIRILPMAGRDPES-----QRNEMIKKEEERLRASIRRESQQRR 533

  Fly  1099 --EPLPAMDLPAGI--PGEGDCLVEGKTYANNTIVPATAPCDVSCKCISSLVACQQMECKLPENL 1159
              |......|.||.  |...|...||:.             .:|...|.|
Zfish   534 MREKQHQRGLNAGYLEPDRYDEDEEGEE-------------SISLAAIKS--------------- 570

  Fly  1160 EKCTVAADLLDGCCPTYICDESTESAEKDEESTAKPDNKIDEDVSEISTEEIPKDVIMPTGITEQ 1224
             |......|.:.....|..| |.|.:::|:........::|.
Zfish   571 -KYKGGGGLREERARIYSSD-SDEGSDEDKAQRLMKAKRLDS----------------------- 610

  Fly  1225 PLSHVKPDEEIQPVTSVPAQFDESTTAKVDKKPIDESAEDKKPIGESEED 1274
                   |||.:......|:.||.:.:|..||.:....||:...||.:.|
Zfish   611 -------DEEGENSGKRKAEEDEESASKKPKKYVISDEEDEDGDGERDGD 653

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tnc	NP_001247300.1	VWC	235..296	CDD:214564
		PHA02664	<433..595	CDD:177447	27/118 (23%)
		Ehrlichia_rpt	529..1065	CDD:118064	118/566 (21%)
		DUF863	<1684..>1788	CDD:283539
		VWC	2762..>2805	CDD:302663
leo1	NP_996950.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..336		87/395 (22%)
		PHA02664	<161..260	CDD:177447	33/150 (22%)
		Leo1	352..510	CDD:281933	37/212 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	526..560		8/33 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	584..696		20/101 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1181
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900