Protein Alignment tnc and CG34417

DIOPT Version :9

• Sequence 1: NP_001247300.1
• Gene: tnc / 42990
• FlyBaseID: FBgn0039257
• Length: 2819
• Species: Drosophila melanogaster
• Sequence 2: NP_001259282.1
• Gene: CG34417 / 31591
• FlyBaseID: FBgn0085446
• Length: 5182
• Species: Drosophila melanogaster
• Alignment Length: 2846
• Identity: 598/2846 - (21%)
• Similarity: 997/2846 - (35%)
• Gaps: 764/2846 - (26%)

  Fly   191 VRYSCDHENELDF----MDQSTTT-----TTTTVRPTTGFILASTMTPPTTTDCIHDGEIFADGA 246
            ||.|....:||.|    :.|..||     |::.|.|........|:......:.::.|.:    |
  Fly    99 VRDSTSPTHELRFHSMTLSQPNTTGWDVQTSSEVSPDGRAYRTETLAKTDGVEKLNGGGL----A 159

  Fly   247 SLKGKNACEHCYCMRGDIVCAVQECEVPMMAANGKSCRAMPAAEGECCPSNYVCE-DDSSTTEI- 309
            ..||:|........:||                               ..|:|.: .|||.|::
  Fly   160 EFKGRNEQRSSASHQGD-------------------------------DKNFVKQASDSSKTQLQ 193

  Fly   310 ------------VEITTPESATSVPAKGI-------HAEIPKEDVDLQE---------HIDDDDK 346
                        .|:....::||..:|.:       :.:.|:..:|.||         ..:.|.:
  Fly   194 ETVVFGDETSGRTEMKMSSTSTSSSSKVVSSSSTVEYGDEPRYLLDNQEKPHKQHQTREWEQDQR 258

  Fly   347 NKETATIPSAELGSGEIEEEEEEKDKATTVAPVQVTDEKDFSFEPESSTAGIPSDSRIDLPSSTE 411
            .:|.           .|:|:.:|:.    :...|:..:::|..:.:     |....:|......:
  Fly   259 RQEQ-----------RIQEQRQEQQ----IRQEQLQRQEEFQRQEQ-----IQRQEQIQRQEQVQ 303

  Fly   412 ESKESSTEAAEE-DIVKIVTTPE--PEGSGEEDVPKPSQIPEKEITE-----DELIKVSTSAPAK 468
            ..:|..||:.|: :..:.|.|.:  .|.....|:.|.|...::.:..     .|:|..:...|
  Fly   304 RQQERFTESREQSNSTRNVQTQQHYEENKRYVDMDKASPEYQRHVQHLMEQPGEIISNTVEYP-- 366

  Fly   469 ASPEEEVVTATTSAPTEEDVKPTTAGTI--SEEEEEGKPTPAEEGSGEEEKDVKVTAAPEETEDE 531
             .|..:::|.         ||....|||  ::..|..:.||::..:..::.:       .:|.::
  Fly   367 -KPNVKMITT---------VKRLPDGTIVKNKRYETEQLTPSQSHTTHKQTN-------NQTHNQ 414

  Fly   532 AKPTSAPVASDEKEQEPKPSEGSGDEELDLKPTTAPTAGATSASEESEEQDEGKSTEAPTSVDDI 596
               |...|.:..:||:.:.|:                   |....::.||.....:::.:||...
  Fly   415 ---TRNQVHNQRREQDEQDSQ-------------------TRDVVDNVEQKHVTESQSFSSVKKS 457

  Fly   597 EPAKPTESSEEASGEGEDVAKETTPAGEASIAGEEEIVKGTTPAGEPSSEGDEEIVKGTTPAEES 661
            .....||::.|...|.:|..:.|:          ..:.|..||:..|.|....:     :||::.
  Fly   458 SRRFSTETTSETVEEYDDRDQPTS----------RVVQKAPTPSYAPPSHSPRQ-----SPAKDF 507

  Fly   662 SSESEDELTKVTTPAGEPSVAGEEEIAKETTPAGEPSIAGEEEIVKVTTPAGESSIAGEEEIVKV 726
            |:.            |.|||...:  |.:..|:..|.|||||.:|
  Fly   508 STH------------GFPSVRPNK--ATQEYPSQRPGIAGEEVVV-------------------- 538

  Fly   727 TTPAGESSSEGEEEIIKVTTPAGESSSEGDEEIVKESTPAGEPISEGEEDVIKATTSAPKSDIEG 791
                                ...|.|.:     ||:.|.:...|   |.:|:......|:
  Fly   539 --------------------VRSEKSRQ-----VKQQTSSQRTI---ETEVVGDDYQEPQ----- 570

  Fly   792 VKEPETATEVPAEEVEDFAKPTTPIAEAEEEPIAGTPIPTDGISGEEEIVKGTTPQTLEEQPEIS 856
             :.|:...|.|....|..|....|:    ||..:....|:         |:.||..|..:||:..
  Fly   571 -RSPQKLREAPTPSWEQPATRRQPV----EEDFSTHGFPS---------VRTTTTSTRPDQPDGE 621

  Fly   857 EESTEVPVAEDDLSS-STSASAIASSTEGVQDAASETT--SSAPARAGDKDEAATTVPTAQDKDD 918
            ...|...|:.:..:: .|:...|..:.....:|.|.:|  |.:|.|:..:|:.|::......|..
  Fly   622 VLHTSKTVSRNQSANRKTNTERIIETQVEHPNAPSHSTPRSGSPRRSQPRDDYASSPRGPAGKPS 686

  Fly   919 EEVEQDATDLPVEDVVQSTTAKTTTTEQP-------KEESSTEAEDA-EIEVTTSSPADK----- 970
            :....:...        |||.|||||.:|       ||.....|..| ...:.:|||||.
  Fly   687 QSRPSNTGG--------STTTKTTTTSEPLTRRQLQKEREVDAAHRAFAASLRSSSPADSTTSVG 743

  Fly   971 --QEVPEAEPAD------KDHKDEEDVQTATDLPIKSDIGPPVVDTEATTGQPETSD--ETATDK 1025
              .:.|.:..:.      :..:...|.|..::   .|.|....| |..|||...||:  :|.|.|
  Fly   744 SHHQTPRSSVSSNRTFRREMREGSHDSQAPSE---SSRISSTTV-TRHTTGGNVTSNTIKTKTTK 804

  Fly  1026 PPSVYLPP-------GGEKDTEKEDETTATEPSVQEEPSKPVDISPVSQEVPSSTAKVDNR---N 1080
            |......|       ||...|.....||.:.||  ..|:.|...:|.: ..|:|:|..||:   .
  Fly   805 PVKTASEPRSPTPKAGGSVTTTTTTITTKSSPS--PAPASPTTAAPPT-SAPASSAPPDNKLSQY 866

  Fly  1081 DFETEKP----TLPPSGEDQSSEPLPAMDLPAGIPGEGDCLVEGKTYANNTIVPATAPCDVSCKC 1141
            .:.|.||    :|||:             .|..|..| ..|...:.....|....||..|
  Fly   867 TYTTTKPGDIFSLPPT-------------TPPTINNE-PTLTTTRNTTTTTTTTTTATSD----- 912

  Fly  1142 ISSLVACQQMECKLPENLEKCTVAADLLDGCCPTYICDESTESA-EKDEESTAKPDNKIDEDVSE 1205
                            ||:                  :...:|| |...::.::|..|:....:|
  Fly   913 ----------------NLQ------------------NHPKKSAIEPATDTDSQPIRKVKLSANE 943

  Fly  1206 IS-TEEIP---KDVIMPTGITEQPLSHVKPDEEIQPVTSVPAQF----DE--------STTAKVD 1254
            .. .||.|   :.........|.|.:   |:....|....|.|.    ||        |.:..|:
  Fly   944 AKVVEEAPCVRRQYYQLGNEGENPET---PESSGTPANKKPHQMRRPHDEPEPQLRRSSKSPSVE 1005

  Fly  1255 KKPID-ESAEDKKPIGESEEDSKPIDE---SEE-------DKKPVEESAEDKKPVEDSEEKEKPL 1308
            .:.:. |:..:.:.:.:..|.|  |||   .||       .|.|...:....||...|:..|||.
  Fly  1006 PRQVQRETTFEGRRVSQDREIS--IDELILIEETSGAPGSPKIPSPRAQSPGKPATRSQSPEKPQ 1068

  Fly  1309 PTVIPASEIEKES---KPEDEKKTEADFAAPTEQ-PEATTPAQIADTAEKEVDDKLA-TTSAPVS 1368
            |...|....|||.   |...|..|.:.   |.:| |.|.:|.:.....:.:|..:.: ....|.:
  Fly  1069 PRATPRQSPEKEQPAFKQTHEVYTPSQ---PEKQFPRARSPEKTPGWTQPQVSPRQSPEKQLPRA 1130

  Fly  1369 GEDELKPADEKKRTETAQIPDAEIPASTDEPESSTE---LPTVDLDKKPEED-----STKGTEAP 1425
            ...|..||..:......|.|:.:||    :|::..:   ||.:...:.||:.     ..|..::|
  Fly  1131 QSPEKVPAVRQPSVSPRQSPEKQIP----DPKTRDQGPGLPRISPRQSPEKQLPKDVPQKSRQSP 1191

  Fly  1426 ESDKVPEVPTSASTENEIEESDKFTTVAPPKISASDETEPTAEEDLVPATFEPIESEFEVSTKKP 1490
            |.|    :......|.||..|...||        ...|.....|:.:  |.|.......:|.|||
  Fly  1192 EKD----LTNQQRREEEIFRSTITTT--------QKRTTNNLNEEFI--TNERDNQNQPISEKKP 1242

  Fly  1491 AVQGPPLPTLAPAQPEKKPVDAETSTEADISTEPSAEVEKEASGETSES---------------- 1539
            .:.       |.|:|..||.:...|.:...   ||...|.||..|..||
  Fly  1243 QIP-------ANAEPNTKPSETIESPDGGF---PSKTTEVEAQPEVKESPTYRKKGLTRRETFED 1297

  Fly  1540 --------DNEIDAGASSTPVPVSADEDKTPS--TEKTVEADDKFTTVAPLAGDEEESNLPKL-- 1592
                    :.:.|...:.|..|.:..||...|  |.:|::     ..:.....|:|:....::
  Fly  1298 RCRQILGMEEDGDTQGTYTERPNNEQEDVNVSHTTIETIQ-----VKIEDCPNDDEDDKPRRVTE 1357

  Fly  1593 -------PQDIFEEEAPVAVTTA------------APSKDDGEQKP--VEVEEKPIEDGQKPIED 1636
                   |:...|||..|.||.|            :|.::|..:.|  .|..:.|..|.:.|
  Fly  1358 TYVVRTQPKIKVEEELFVDVTEAEDVEILVNPSKKSPKEEDSPKYPKGPETPKSPRNDQRIP--- 1419

  Fly  1637 ETSTPTSSENEIEPESDRATTIAPSKEE--PSEPSTGAPTKDEPAEPSTDAPESDESKETPESEV 1699
              |.|...::.::.:::. |...|.::|  |.||.|....|:.|..|..||...:.::||
  Fly  1420 --SIPKKGQSPVQFKTEE-TPRYPQEQERYPKEPETSQYPKESPRNPKEDAETININEET----- 1476

  Fly  1700 PTTVAPAGEKIPTSSITPDEE---------PTATSAPVAKPDEDVEKETSTEIPTDAPASSEEDE 1755
            ...:...|.|.|:...:|..|         |:.|::|...|      .:..:||      :|.:.
  Fly  1477 TIVITKEGSKSPSPRWSPSPERRVPKSQQPPSPTASPSVSP------VSGRKIP------NEVES 1529

  Fly  1756 NSSTDQI----PSEVPEK---KPETPAQTPEEGDIVGATAAPTTSDEVPPVQRLPEEVLAEIPQP 1813
            |..|::|    ...|.||   :|.||:.|             |......|.|::||.|    |:.
  Fly  1530 NFVTEKIIDCRGKTVVEKISQRPRTPSPT-------------TPKKNTKPSQKIPERV----PET 1577

  Fly  1814 STETGIKQQDET--TAAPSIDRKEPYVTEIDEEATTVAPISEKDEKPTEEEKPVEQKPTGEEPSE 1876
            .:|.....:.||  |.:.|:.:.|   ||.....||      |.::|...::|..:.|.|:.|.:
  Fly  1578 ESEPEKDSESETKKTTSVSVTKTE---TERRNSRTT------KTKQPLPLKEPQSKVPAGKSPRK 1633

  Fly  1877 E----EEKEKPIEQDVSTEGPVSTEASEAGSTESSEEVKPSTEGEVAEKPEDKQPSSTAQAPVET 1937
            :    .:::..:|:   |....:|..:..|...|.....||.:..:...|. ||.:|..|.
  Fly  1634 DSLTGRKRDSLVEE---TRITTTTTTTRQGRKPSDTNGSPSIKDRLRSSPR-KQKTSPQQT---- 1690

  Fly  1938 IPEISTELPAQDGDKPTSEAPVDSDEDTSAPSDEKIPSVSGEEVEGPEVTTASPQAAEEDELKTP 2002
                .|..|||     |.....|.|.|:|:| |.....|..|......::..:....:....|:|
  Fly  1691 ----RTPTPAQ-----TRNPEDDVDGDSSSP-DASPTRVGNERRRSSNISVHTEIIIDHMAPKSP 1745

  Fly  2003 AESE---------PSSTDKVPETEYQ------------KPEDETKADETPESVTQVSDVA--TST 2044
            ....         ||...|:|.||.:            |.|..|::  |.|::.::|...  ...
  Fly  1746 KTERRSQGGTGNVPSPIRKLPVTERKESAPVPRVTRRDKAEKVTRS--TSENIIKMSGTKPHPEM 1808

  Fly  2045 SAPVAGGDIEKDEQATTASPEEEEEIKPTIAPAAEIPQPSEKEPVDEQEVESGTKATPAESDGQP 2109
            |:...|||..:..:..|.......|.:  |..|.:|    |...:|.|:.:|..:.:|
  Fly  1809 SSLKPGGDRSRPSKCCTTKTINLSEQR--INTATDI----EGVIIDIQQAKSSREPSP------- 1860

  Fly  2110 IDEIAPATSGPIDEASTAAPTKEESTTVASAASPAVHDDEIKDVTTTQPVADEKEVAAPQDETKT 2174
             |.|.|          |..|.:.|:      ..|...|                .|..|.||.:.
  Fly  1861 -DRIVP----------TPVPAELET------GKPRYPD----------------VVQEPDDEPRR 1892

  Fly  2175 SIDVSTDSPTAQDDEKQDKTEAPVAPTTVSSPTADSAADSSTPTVEVPSPVE--IDTKPMDDIMS 2237
            ...| |:.|.. ::|.|......::....|:.......|:  ||||.|..::  ::|...|:.:
  Fly  1893 KPQV-TNIPIF-EEESQTYVGCQISELHSSNGIEVDILDN--PTVEAPKSLDYPVNTPDTDESL- 1952

  Fly  2238 QTIAPHTADGAASTSTEDEDQAPVTVSPQDAEKTPVSPAPQDSDKTPSSEAPQDADEIPATATPL 2302
              ::.|......:.|.| :.:.|...:|...|....:..|::.|...|..  |..|:...||
  Fly  1953 --LSVHEKVSRFTHSAE-KVKEPKVSAPFSREFDVNAKIPENDDCLLSIN--QKVDKFLRTA--- 2009

  Fly  2303 DDNKIPATVAPQTDDGVPATAAPLDEDKIQ---TTAAPLDEEKIPSTAAPLDDEKIPAPVSP--- 2361
             :|.|..|..|...:........:||:.::   |.:......|...||     ||: ||..|
  Fly  2010 -ENVIRPTSLPSRPEIERPGLEEIDEELLRDDCTLSVSQKVHKFIDTA-----EKL-APTMPQKS 2067

  Fly  2362 --VVFDVEPSSEKPAVSEYDGEESTEPPV-HDVETSTDEPTSDAKLKPPTSAPATPSESPATEAE 2423
              :|.::|....:.:..|.:.:|.:||.: .|.:...|:.||..:.:...:...|..|:.....:
  Fly  2068 PRLVANIERHISRQSEPERELDEESEPELDRDTDVEDDDQTSQLETEEEITQTVTKKETLKEFKQ 2132

  Fly  2424 IVPET--------AAPE-LEKEVP-----EKATEQPELEKETPEKATE-----QPELE-----KE 2464
            ...||        |.|| |:|:.|     |::...|:.:.:..:|.::     ||:.|     ||
  Fly  2133 QTKETRETRRDSKAEPEKLQKKSPQTKVKEESARVPKYQAKVSQKVSQWEPKKQPQREPKVTQKE 2197

  Fly  2465 TPEKATEQP-ELEKETPEKATE-QPEL-EKEVTDKATEQPESVDEKT-TPEPVVKPSLDSTEEDE 2525
            ||.:..:|| ...|:.|||..: :|:: :||...|..|:||.|.:|| ..||..:|...|  |||
  Fly  2198 TPLEPKKQPLSKVKDEPEKVNKREPKVPQKESQTKLKEEPERVTKKTPQKEPRKEPLRQS--EDE 2260

  Fly  2526 ESVESEEESADK---KDKNKETEEDTDKKHEEPEVPAVVSE-IPQPSEEAVP-------TTGHPL 2579
            .....|||..|:   ..|...|..:..::.:....|:|..: .|:......|       |.|.|
  Fly  2261 PEFSPEEEFDDEPLPMTKTHTTAIEMKRQKDILNRPSVFGQRTPERKSSTTPSPTKLNGTRGRP- 2324

  Fly  2580 FPHLASSTTTPPAVDDRVGEEDEENTTVKLSSSTTTSTTESPVTSAPSTTTVASQQQQPITPPPY 2644
                  |.:|....:::....::.....|..:..||.:..||..|.|..||..|::.:.|:...:
  Fly  2325 ------SPSTNLITEEKRSYRNQVTNVSKPGTRKTTPSANSPAQSPPPKTTSISKRMEQISQQSW 2383

  Fly  2645 GHAPEYEDEYDEEEVFGPGTCRYAGKLYVSAQQIPRDDPCDFCFCFRSDIICLQQSCPPPIAGCH 2709
                ..:|...:.||.||     |...::|.:.                    |...|.|.:
  Fly  2384 ----VVQDVDVDVEVVGP-----APPSHISEKP--------------------QGKSPSPTS--- 2416

  Fly  2710 EEPISGFCCPRYECPVSMAAVLNITTSTTTTSTTLPPHFLHYSHGEAVKHT 2760
            ...:|.  .|........:..|| ||||.||:||        .|...:|.|
  Fly  2417 SRSLSR--SPSRSPSRRTSTNLN-TTSTNTTTTT--------EHPSTIKTT 2456

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tnc	NP_001247300.1	VWC	235..296	CDD:214564	7/60 (12%)
		PHA02664	<433..595	CDD:177447	28/170 (16%)
		Ehrlichia_rpt	529..1065	CDD:118064	118/568 (21%)
		DUF863	<1684..>1788	CDD:283539	26/119 (22%)
		VWC	2762..>2805	CDD:302663
CG34417	NP_001259282.1	Smoothelin	2594..2636	CDD:289290
		Smoothelin	3127..3176	CDD:289290
		GBP_C	<3810..3882	CDD:303769
		coiled coil	3857..3868	CDD:293879
		CH	5076..5179	CDD:237981

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1181
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900