DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tnc and Ibsp

DIOPT Version :9

Sequence 1:	NP_001247300.1	Gene:	tnc / 42990	FlyBaseID:	FBgn0039257	Length:	2819	Species:	Drosophila melanogaster
Sequence 2:	NP_036719.2	Gene:	Ibsp / 24477	RGDID:	2855	Length:	319	Species:	Rattus norvegicus

Alignment Length:	276	Identity:	67/276 - (24%)
Similarity:	109/276 - (39%)	Gaps:	54/276 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   504 KPTPAEEGSGEEEKDVKVTAAPEETEDEAKPTSAPVASDEKEQEPKPSEGSGDEELDLKPTTAPT 568
            |..|.:.||...|::....::.||.|:|        .:..:|:..:.|||:.|:|.:.:  .|..
  Rat    56 KRFPVQGGSDSSEENGDGDSSEEEGEEE--------ETSNEEENNEDSEGNEDQEAEAE--NATL 110

  Fly   569 AGATSASEESEEQDEGK----STEAPTSVDDIEPAKPTESSEEASGEGEDVAKETTPAGEASIAG 629
            :|.|::.......|.||    :.:.|....|.|...|  ..:|:..|.|:..:|.....||.:..
  Rat   111 SGVTASYGVETTADAGKLELAALQLPKKAGDAEGKAP--KMKESDEEEEEEEEEENENEEAEVDE 173

  Fly   630 EEEIVKGTTPAGEPSSEGDEEIVKGTTPAEESSSESEDELTKVTTPAGEPSVAGEEEIA------ 688
            .|::|.||       |....|:..|..|:...:.|..:| ..||....|.:.||..|:.
  Rat   174 NEQVVNGT-------STNSTEVDGGNGPSGGDNGEEAEE-ASVTEAGAEGTTAGARELTSYGTTT 230

  Fly   689 -------KETTPAGEPSIAGEEEIVKVTTPAGESSIA--GE--EEIVKVTTPAGESSSEGEEEII 742
                   ::|||  .|...|     ..:.||.:||..  ||  |:|......|.|:..|...|
  Rat   231 AVLLNGFQQTTP--PPEAYG-----TTSPPARKSSTVEYGEEYEQIGNEYNTAYETYDENNGE-- 286

  Fly   743 KVTTPAGESSSEGDEE 758
                |.|::....::|
  Rat   287 ----PRGDTYRAYEDE 298

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tnc	NP_001247300.1	VWC	235..296	CDD:214564
		PHA02664	<433..595	CDD:177447	22/94 (23%)
		Ehrlichia_rpt	529..1065	CDD:118064	60/251 (24%)
		DUF863	<1684..>1788	CDD:283539
		VWC	2762..>2805	CDD:302663
Ibsp	NP_036719.2	BSP_II	17..316	CDD:283165	67/276 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	59..116		17/66 (26%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	135..224		26/98 (27%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	237..263		9/32 (28%)
		Cell attachment site	288..290		0/1 (0%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1181
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900