DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment tnc and Ibsp

DIOPT Version :9

Sequence 1:NP_001247300.1 Gene:tnc / 42990 FlyBaseID:FBgn0039257 Length:2819 Species:Drosophila melanogaster
Sequence 2:NP_032344.2 Gene:Ibsp / 15891 MGIID:96389 Length:324 Species:Mus musculus


Alignment Length:286 Identity:70/286 - (24%)
Similarity:107/286 - (37%) Gaps:69/286 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   504 KPTPAEEGSGEEEKDVKVTAAPEETEDEAKPTSAPVASDEKEQEPKPSEGSGDEELDLKPTTAPT 568
            |..|.:.||...|::....::.||.|:|        .:..:|:..:.|||:.|:|.:.:.:|..|
Mouse    56 KRFPVQGGSDSSEENGDGDSSEEEGEEE--------ETSNEEENNEDSEGNEDQEAEAENSTLST 112

  Fly   569 AGATSASEESEEQDEGKSTE-----APTSVDDIEPAKP--TESSEEASGEGEDVAKETTPAGEAS 626
            ....:||..:|...:.::.|     .|....|.|...|  .||.||...|.|:...|..   ||.
Mouse   113 LSGVTASYGAETTPQAQTFELAALQLPKKAGDAESRAPKVKESDEEEEEEEEEEENENE---EAE 174

  Fly   627 IAGEEEIVKGTT------PAGEPSSEGDEEIVKGTTPAEESSSESEDELTKVTTPAGEPSVAGEE 685
            :...|..|.||:      ..|..||.||            :..|:|.|...||....|.:..|  
Mouse   175 VDENELAVNGTSTNSTEVDGGNGSSGGD------------NGEEAEAEEASVTEAGAEGTTGG-- 225

  Fly   686 EIAKETTPAGEPS---IAGEEEIVKVTTPAGESSIAGEEEIVKVTTPAGESSSE----GEEEIIK 743
               :|.|..|..:   :.|.::    |||..|:        ...|:|....||.    ||.|   
Mouse   226 ---RELTSVGTQTAVLLNGFQQ----TTPPPEA--------YGTTSPPIRKSSTVEYGGEYE--- 272

  Fly   744 VTTPAGESSSEGDEEIVKESTPAGEP 769
                  ::.:|.:.|........|||
Mouse   273 ------QTGNEYNNEYEVYDNENGEP 292

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
tncNP_001247300.1 VWC 235..296 CDD:214564
PHA02664 <433..595 CDD:177447 22/95 (23%)
Ehrlichia_rpt 529..1065 CDD:118064 63/261 (24%)
DUF863 <1684..>1788 CDD:283539
VWC 2762..>2805 CDD:302663
IbspNP_032344.2 BSP_II 17..321 CDD:283165 70/286 (24%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 60..228 48/195 (25%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 243..263 6/31 (19%)
Cell attachment site. /evidence=ECO:0000255 293..295 70/286 (24%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1181
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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