Protein Alignment AFF1 and MSN1

DIOPT Version :10

• Sequence 1: NP_001160165.1
• Gene: AFF1 / 4299
• HGNCID: 7135
• Length: 1218
• Species: Homo sapiens
• Sequence 2: NP_014525.1
• Gene: MSN1 / 854033
• SGDID: S000005476
• Length: 382
• Species: Saccharomyces cerevisiae
• Alignment Length: 325
• Identity: 68/325 - (20%)
• Similarity: 127/325 - (39%)
• Gaps: 66/325 - (20%)

Human     1 MAFTERVNSSGNSLYNDDRNLL--RIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKG------ 57
            ||..:.:   |.|..|::..:|  |:.|.|||.........|...::.|..:.|.....
Yeast     1 MASNQHI---GASNLNENEAILTNRVAELERRMSMFEGIFHALSNRLDLHFKKYDVVVNSQQQQI 62

Human    58 DELSSRIQNMLGNYEEVKEFLSTK-SHT-HRLDASENRLGKPKYPLIPDKGSSIPSS-SFHTSVH 119
            :||::.:..:|.:.:...|.||.| |.| |.:.|:...|.:...|.....|::.|.: ..:|||
Yeast    63 NELTAFLSTLLNDQQRHAEILSEKLSGTLHGVSATSISLSQTLDPQGFTDGTTAPGAPRNYTSV- 126

Human   120 HQSIHTPASGPLSVGNISHNPKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFGSSHHKKG 184
                      |:      :|.:.|.|:.|          |...::.|.:|.|..   .|..:.|.
Yeast   127 ----------PM------NNDQTAHPQNE----------GAVSNETLFEDILNG---NSQENDKS 162

Human   185 DRRADGDHCASVTDSAPERELSPLISLP-----SPVPPLSPIHSNQQTLPRTQG--SSKVHGSSN 242
            .::.:..:..|..:::....:....:.|     :.||.|....:|.   |...|  |..::.|||
Yeast   163 QQQTNSSNSISQENNSTNPSVDTRFNKPQNYNSNLVPSLEEYSANP---PNNDGGQSQGLYISSN 224

Human   243 NSKGYCPAKSPKDLAVKVHDKETP--QDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMD 305
            :|:.   .:||.      ..|.:|  ::::.:.||....||......:|: .:::|.....||.:
Yeast   225 SSQS---RQSPN------LQKVSPNHENAVESNAQESVPTFEEEQYETKT-GLKRKRIVCTRPFE 279

Human   306  305
            Yeast   280  279

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AFF1	NP_001160165.1	AF-4	15..527	CDD:461550	64/311 (21%)
		PHA03247	<533..800	CDD:223021
		AF-4_C	957..1218	CDD:465894
MSN1	NP_014525.1	GCR1_C	278..356	CDD:432628	0/2 (0%)