DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mah and Slc38a8

DIOPT Version :9

Sequence 1:	NP_651316.1	Gene:	mah / 42988	FlyBaseID:	FBgn0285912	Length:	527	Species:	Drosophila melanogaster
Sequence 2:	XP_006255783.1	Gene:	Slc38a8 / 502208	RGDID:	1560237	Length:	476	Species:	Rattus norvegicus

Alignment Length:	473	Identity:	91/473 - (19%)
Similarity:	169/473 - (35%)	Gaps:	127/473 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    81 FPFV------TLPALLVKLGYFGILLVLSIIILQIYTSFLLSQCWTMAELLDPSIQQKRNYPYAA 139
            ||:.      .:|..||.|  ..::.::|.:::..|.:.:..|.                 .|..
  Rat    45 FPWAFYKAGGLVPTFLVAL--VSLVFLISGLVILGYAASVSGQT-----------------TYQG 90

  Fly   140 LAELAYGPYMSLLVSVLLDLSIFAMAVPSVVMAAQNLEGVV--LRMSAGQ--YNFSYCYWAIIVG 200
            :.....||.|..|.......::..::|..:.:....||.:.  |...|.|  |........:|..
  Rat    91 VVRELCGPAMGKLCEACFLTNLLMISVAFLRVIGDQLEKLCDSLLPDAPQPWYAAQSFTLPLISV 155

  Fly   201 LVICPLMWL---GSPKHMRGLAIIAVCVMIVIVALLWFCLFAAPAIGTPFEGISLELPGFLTVLN 262
            |||.||..|   ...::...|..:|.|.:.:::.:.:: |:....|..|  |..|....:.:|.:
  Rat   156 LVIFPLSALRDIALQEYTSILGTLAACYLALVITVQYY-LWPQGLIRQP--GPLLSPSPWTSVFS 217

  Fly   263 SYSILAFQFDIHPVLLTLQIDMKQKSQVSW--AALIGIAITCSVAIFGSIIAAYKFGSMIADNLL 325
            .:..:.|.|..|...:::...|:.:|...|  .:::.:...|.|.....:.....||:.::.::|
  Rat   218 VFPTICFGFQCHEAAVSIYCSMQNQSLPHWTLVSVLSLMACCLVYTLTGVYGFLTFGTEVSADIL 282

  Fly   326 QSLP-TSVPFYVMLILMALQLCFSVTVASSAMFM---QIENYFK------------LPESLSFKR 374
            .|.| ......|..:|.|:.:   |||....:|:   .:::::|            ...|..:.|
  Rat   283 MSYPGNDTAIIVARVLFAVSI---VTVYPIVLFLGRSVMQDFWKKSYWATQGSPVLADPSGPWVR 344

  Fly   375 MLIRSSVLALEVLVAEFVPSFDALMDVVGGTITGPLVFILPPLLYRRIRRMERVHQRIAAEASYG 439
            :.:....:|:.:.:|.|:|....::.|:|| ::...:||.|.|..            |:|
  Rat   345 LPLTFLWVAVTLAMALFLPDLSEIIGVIGG-LSAFFIFIFPGLCL------------ISA----- 391

  Fly   440 SLPLDLNYDPVDLEMEPLLVISPPTTPR--GC-------------W-------LRFVRLLHRLEC 482
                      ||.|         |..||  ||             |       .|..|:.|||
  Rat   392 ----------VDTE---------PIGPRVKGCSGRLYANCFVSTRWFLEQAVGFRHGRVHHRL-- 435

  Fly   483 DVSCTMAVLIFGLLATFL 500
                      ||...:||
  Rat   436 ----------FGFQDSFL 443

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mah	NP_651316.1	SLC5-6-like_sbd	110..426	CDD:294310	64/340 (19%)
Slc38a8	XP_006255783.1	SLC5-6-like_sbd	29..386	CDD:294310	70/366 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352555
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840