DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mah and slc38a4

DIOPT Version :9

Sequence 1:	NP_651316.1	Gene:	mah / 42988	FlyBaseID:	FBgn0285912	Length:	527	Species:	Drosophila melanogaster
Sequence 2:	NP_001005944.2	Gene:	slc38a4 / 449771	ZFINID:	ZDB-GENE-041010-14	Length:	538	Species:	Danio rerio

Alignment Length:	405	Identity:	91/405 - (22%)
Similarity:	158/405 - (39%)	Gaps:	99/405 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    98 ILLVLSIIILQIYTSFLLSQCWTMAELLDPSIQQKRNYPYAALAELAYG--PYMSLLVSVLLD-- 158
            ::|:|.:.||.:|:          ..||..:.::..:..|..|.|.|:|  ..|:...|:.|.
Zfish   106 VILLLGVAILSLYS----------VHLLLVTAKEGGSLIYEKLGERAFGWPGKMAAFGSITLQNI 160

  Fly   159 ------LSIFAMAVPSVVMAAQNLE-------------------GVVLRMS-----------AGQ 187
                  |.|....:|.|:.|...||                   |::|.:|           :|
Zfish   161 GAMSSYLFIVKYELPEVIRAFLGLEESSGEWYLNGNYVVVLVSIGIILPLSLLKNLGYLGYTSG- 224

  Fly   188 YNFSYCYWAIIVGLVI-------CPLMWL---GSPKHMRGLAIIAVCVMIVIVALLWFCLFAAPA 242
              ||.......:|::|       |||.:.   ||...:.|...||:..:....||.:....||.|
Zfish   225 --FSLSCMVFFLGVLIYKKTILPCPLPFFFEHGSNVSINGSDAIALYGLHNASALAYMSETAANA 287

  Fly   243 IG--TPFEGISLEL------------PGFLTVLNSYS-----ILAFQFDIHPVLLTLQIDMKQKS 288
            :.  ||... |::.            |.:. :.||.:     ||||.|..||.:|.:..::|.:|
Zfish   288 VDPHTPLHD-SVQFSAHPEDHQDMCTPKYF-IFNSQTVYTVPILAFAFVCHPEVLPIYSELKNRS 350

  Fly   289 QVSWAALIGIAITCSV------AIFGSIIAAYKFGSMIADNLLQSLPTSVPFYVMLILMALQLCF 347
            :....::..::|...:      |:||.:    .|...:...||.:......|..||:::.|.:..
Zfish   351 RRRMQSVSNLSILAMLVMYLLSALFGYL----TFYDHVEAELLHTFTKVYKFDTMLLMVRLAVLT 411

  Fly   348 SVTVASSAMFMQIEN-----YFKLPESLSFKRMLIRSSVLALEVLVAEFVPSFDALMDVVGGTIT 407
            :||:....:...|.:     .|...|....:..||.:::||...|:..|||:...:...:|.:..
Zfish   412 AVTLTVPIVLFPIRSSVITLCFAGKEFSWIRHFLIAAAILAFNNLLVIFVPTIRDIFGFIGSSAA 476

  Fly   408 GPLVFILPPLLYRRI 422
            ..|:||||...|.|:
Zfish   477 TMLIFILPAAFYLRL 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mah	NP_651316.1	SLC5-6-like_sbd	110..426	CDD:294310	87/393 (22%)
slc38a4	NP_001005944.2	DUF4404	3..90	CDD:291055
		SdaC	68..520	CDD:223884	91/405 (22%)
		SLC5-6-like_sbd	72..525	CDD:294310	91/405 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	1	1.010	-	-		D403368at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920