DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mah and CG1139

DIOPT Version :9

Sequence 1:	NP_651316.1	Gene:	mah / 42988	FlyBaseID:	FBgn0285912	Length:	527	Species:	Drosophila melanogaster
Sequence 2:	NP_647686.1	Gene:	CG1139 / 38264	FlyBaseID:	FBgn0035300	Length:	451	Species:	Drosophila melanogaster

Alignment Length:	512	Identity:	97/512 - (18%)
Similarity:	193/512 - (37%)	Gaps:	129/512 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 HQHDQL--PFLRRSRFSALPHFRAYEDEPENLSLFIAILYVVDLFGIFPFVTLPALLVKLGYF-G 97
            |||.:|  |   .:.|....||.       ..|:...:|            .:|:.....||. |
  Fly    34 HQHRELKNP---TTNFQTFAHFL-------KASVGTGVL------------AMPSAFAHAGYVNG 76

  Fly    98 ILLVLSIIILQIYTSFLLSQCWTMAELLDPSIQQKRNYPYAALAE-----LAYG-PYMSLLVSV- 155
            .||.|.|..|.:|...:|.:|..:       :.:::..||.:.::     |..| |::..|..:
  Fly    77 TLLTLIIGSLALYCLHILIKCMYI-------LCKRQRVPYVSFSQAMNLGLKQGPPWLRCLAPIA 134

  Fly   156 ------LLDLSIFAMAVPSVVMAAQNLEGVVLRMSAGQYNFSYCYWAIIVG--LVICPLMWLGSP 212
                  .|....|.:....||..|::::.:|     .:|   ...|.:.:.  ::|.||:.:.|.
  Fly   135 VPFVDGFLAFYHFGICCVYVVFIAESIKQLV-----DEY---LVVWDVRIHMCIIIVPLLLIYSI 191

  Fly   213 KHMRGLAIIAVCVMIVIVA----LLWFCLFAAPAIG--TPFEGISLELPGFL-TVLNSYSILAFQ 270
            |:::.||..:....::::.    :|::.....|.:.  .||.... :||.|. |||       |.
  Fly   192 KNLKLLAPFSSAANLLLLVGFGIILYYIFEELPPLSERDPFVAAG-KLPTFFGTVL-------FA 248

  Fly   271 FDIHPVLLTLQIDM-KQKSQVSWAALI--GIAITCSVAIFGSIIAAYKFGSMIADNLLQSLPTS- 331
            .:...|:|.::.:| ..||.|....::  |::|...:.:.......:|:|:....::..::|.|
  Fly   249 LEAVGVILAIEENMATPKSFVGPCGILNSGMSIVLGLYVLLGFFGYWKYGNESEGSITLNIPQSE 313

  Fly   332 VPFYVMLILMALQLCFSVTV-----ASSAMFMQIENYFKLPESLSFKRMLIRSSVLALEVLVAEF 391
            :|..|:.:..|:....|..:     |.......:...||.... :|..::.|:.::.|....|..
  Fly   314 IPAQVVKVFFAITTWISYALQGYVTAHILWDKYLAKRFKETRQ-TFYELIFRAIIVLLTFGCAVA 377

  Fly   392 VPSFDALMDVVGGTITGPLVFILPPLLYRRIRRMERVHQRIAAEASYGSLPLDLNYDPVDLEMEP 456
            :|.....:.:||......|..|.|.||            :|..:.:.|       |.|..::
  Fly   378 IPDLSVFLSLVGSFCLSILGLIFPVLL------------QICVQYTEG-------YGPFRIK--- 420

  Fly   457 LLVISPPTTPRGCWLRFVRLLHRLECDVSCTMAVLIFGLLATFLSTYLNIFSLASLF 513
             |:|:                          :.:|.||:....:.||::|..:.:::
  Fly   421 -LIIN--------------------------LLLLCFGIFGGVVGTYVSILDIIAVY 450

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mah	NP_651316.1	SLC5-6-like_sbd	110..426	CDD:294310	66/346 (19%)
CG1139	NP_647686.1	SdaC	36..404	CDD:223884	81/413 (20%)
CG1139	NP_647686.1	SLC5-6-like_sbd	42..444	CDD:294310	92/496 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468321
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740