Protein Alignment mah and SLC36A1

DIOPT Version :10

• Sequence 1: NP_651316.1
• Gene: mah / 42988
• FlyBaseID: FBgn0285912
• Length: 527
• Species: Drosophila melanogaster
• Sequence 2: XP_047272876.1
• Gene: SLC36A1 / 206358
• HGNCID: 18761
• Length: 507
• Species: Homo sapiens
• Alignment Length: 359
• Identity: 67/359 - (18%)
• Similarity: 136/359 - (37%)
• Gaps: 71/359 - (19%)

  Fly   175 NLEGVVL--RMSAGQYNFSYCYWAIIVGLVICPLMWLGSPKHMRGLAIIAVCVMI-VIVALLWFC 236
            |.|.|:|  .|.:..|..|:..:.:::..:          :::|.|:|.::...| ::|:|:...
Human   213 NNETVILTPTMDSRLYMLSFLPFLVLLVFI----------RNLRALSIFSLLANITMLVSLVMIY 267

  Fly   237 LFAAPAIGTPFEGISLELPGFLTVLNSYSILAFQFDIHPVLLTLQIDMKQKSQVSWAALIGIAIT 301
            .|....|..| ..:.|..| :.|....:....|.|:...::|.|:..||...:......:|:.|.
Human   268 QFIVQRIPDP-SHLPLVAP-WKTYPLFFGTAIFSFEGIGMVLPLENKMKDPRKFPLILYLGMVIV 330

  Fly   302 CSVAIFGSIIAAYKFGSMIADNLLQSLPTSVPFYVMLILMALQLCFSVTVASSAMFMQIENYF-- 364
            ..:.|....:...:||:.|..::..:||....:..:.:|.::.:.|:..:........|..:|
Human   331 TILYISLGCLGYLQFGANIQGSITLNLPNCWLYQSVKLLYSIGIFFTYALQFYVPAEIIIPFFVS 395

  Fly   365 KLPESLSF-KRMLIRSSVLALEVLVAEFVPSFDALMDVVGGTITGPLVFILPPLLYRRIRRMERV 428
            :.||.... ..:.:|:.::.|..::|..:|..|.::.:||...:..|..|:||||
Human   396 RAPEHCELVVDLFVRTVLVCLTCILAILIPRLDLVISLVGSVSSSALALIIPPLL---------- 450

  Fly   429 HQRIAAEASYGSLPLDLNYDPVDLEMEPLLVISPPTTPRGCWLRFVRLLHRLECDVSCTMAVLIF 493
              .:....|.|..||.:..|.:                                       :.|.
Human   451 --EVTTFYSEGMSPLTIFKDAL---------------------------------------ISIL 474

  Fly   494 GLLATFLSTYLNIFSLASLFTNNSPCLSNLTKHF 527
            |.:...:.||..::.|  :..:|:|...|.|..|
Human   475 GFVGFVVGTYEALYEL--IQPSNAPIFINSTCAF 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mah	NP_651316.1	SLC5-6-like_sbd	110..426	CDD:444915	52/256 (20%)
SLC36A1	XP_047272876.1	SLC5-6-like_sbd	78..484	CDD:444915	59/333 (18%)