DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mah and Slc36a1

DIOPT Version :9

Sequence 1:	NP_651316.1	Gene:	mah / 42988	FlyBaseID:	FBgn0285912	Length:	527	Species:	Drosophila melanogaster
Sequence 2:	NP_569099.1	Gene:	Slc36a1 / 155205	RGDID:	619801	Length:	475	Species:	Rattus norvegicus

Alignment Length:	522	Identity:	97/522 - (18%)
Similarity:	192/522 - (36%)	Gaps:	134/522 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 AYEDEPENLSL--FIAILYVV------DLFGIFPFVTLPALLVKLG-YFGILLVLSIIILQIYTS 112
            :|:...||.|:  |..:::::      .|.|      ||..:...| ..|.|.:|.|.|:.::..
  Rat    36 SYQRLGENSSMTWFQTLIHLLKGNIGTGLLG------LPLAVKNAGLLLGPLSLLVIGIVAVHCM 94

  Fly   113 FLLSQCWTMAELLDPSIQQKRNYPYAALAE-LAYGPYMS-------------------LLVSVLL 157
            .:|.:|       ...:.::.|.|:....: :.||...|                   |:|:.|.
  Rat    95 GILVKC-------AHHLCRRLNKPFLDYGDTVMYGLECSPSTWIRNHSHWGRRIVDFFLVVTQLG 152

  Fly   158 DLSIF----AMAVPSVVMAA-------QNLEGVVL--RMSAGQYNFSYCYWAIIVGLVICPLMWL 209
            ...::    |.....|:.||       .|.|.|:|  .|.:..|..::..:.:::..:
  Rat   153 FCCVYFVFLADNFKQVIEAANGTTTNCNNNETVILTPTMDSRLYMLTFLPFLVLLSFI------- 210

  Fly   210 GSPKHMRGLAIIAVCVMI-VIVALLWFCLFAAPAIGTPFEGISLELPGFLTVLNSYSILAFQFDI 273
               :::|.|:|.::...| :.|:|:....|....|..| ..:.|..| :.|....:....|.|:.
  Rat   211 ---RNLRILSIFSLLANISMFVSLIMIYQFIVQRIPDP-SHLPLVAP-WKTYPLFFGTAIFAFEG 270

  Fly   274 HPVLLTLQIDMKQKSQVSWAALIGIAITCSVAIFGSIIAAYKFGSMIADNLLQSLPTSVPFYVML 338
            ..|:|.|:..||...:......:|:||...:.|....:...:||:.|..::..:||....:..:.
  Rat   271 IGVVLPLENKMKDSQKFPLILYLGMAIITVLYISLGSLGYLQFGADIKGSITLNLPNCWLYQSVK 335

  Fly   339 IL--------MALQLCFSVTVASSAMFMQIENYFKLPESLSFKRMLIRSSVLALEVLVAEFVPSF 395
            :|        .|||...:..:...|:..::...|:|...||     .|::::.:..::|..:|..
  Rat   336 LLYSIGIFFTYALQFYVAAEIIIPAIVSRVPERFELVVDLS-----ARTAMVCVTCVLAVLIPRL 395

  Fly   396 DALMDVVGGTITGPLVFILPPLLYRRIRRMERVHQRIAAEASYGSLPLDLNYDPVDLEMEPLLVI 460
            |.::.:||...:..|..|:||||            .:......|..||.:..|.:
  Rat   396 DLVISLVGSVSSSALALIIPPLL------------EVTTYYGEGISPLTITKDAL---------- 438

  Fly   461 SPPTTPRGCWLRFVRLLHRLECDVSCTMAVLIFGLLATFLSTYLNIFSLASLFTNNSPCLSNLTK 525
                                         :.|.|.:...:.||.:::.|  :..::|...:|.|.
  Rat   439 -----------------------------ISILGFVGFVVGTYESLWEL--IQPSHSDSSTNSTS 472

  Fly   526 HF 527
            .|
  Rat   473 AF 474

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mah	NP_651316.1	SLC5-6-like_sbd	110..426	CDD:294310	69/357 (19%)
Slc36a1	NP_569099.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..32
Slc36a1	NP_569099.1	SLC5-6-like_sbd	47..452	CDD:382020	86/485 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352571
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.750