Protein Alignment Nmnat and nmnat2

DIOPT Version :10

• Sequence 1: NP_651315.2
• Gene: Nmnat / 42987
• FlyBaseID: FBgn0039254
• Length: 389
• Species: Drosophila melanogaster
• Sequence 2: NP_956298.1
• Gene: nmnat2 / 336257
• ZFINID: ZDB-GENE-030131-8201
• Length: 304
• Species: Danio rerio
• Alignment Length: 307
• Identity: 98/307 - (31%)
• Similarity: 147/307 - (47%)
• Gaps: 71/307 - (23%)

  Fly    37 EETKSLLPRIAFIACGCFSPPTPMHLRMFEIAKDHFEMQGTHRVVGGIISPTHDSYGKKGLASAL 101
            |.||:   .:..::||.|:|.|..|:.|||.|:::....|...|:|||:||.||||||.||..:.
Zfish     3 ENTKT---HVILLSCGSFNPITKGHIHMFEKAREYLHKTGRFIVIGGIVSPVHDSYGKPGLVPSR 64

  Fly   102 DRCAMVKLATQSSNWIRLSDWEVHQNQWMRTQAVLQHH--------------------------- 139
            .|..|.:||.|||:|||:..||.:|:.|..|.:||:||
Zfish    65 HRLTMCQLAVQSSDWIRVDPWECYQDTWQTTCSVLEHHRDLMKRVTGCILSNVNTPSTTPVIGQP 129

  Fly   140 --------QNYINNHINSGGGGG---------------------DDGENTHLPGWLPRGLHDSRD 175
                    ||.:|..:.....|.                     |:..|      |...:.....
Zfish   130 QNETSAIYQNTVNKSVAIKFWGKMSESLGKICCVRPHMDRFTFVDENAN------LGTAMRYEEI 188

  Fly   176 PVHLKLLCGADLLESFAVPGLWAEADIEDIVANHGLVVITRAGSNPGKFIFDSDILTKYQSNITL 240
            .:.:.||||:||||||.:||||.|:|:|.||.:.|:||:.|.|::..:.:..|.:|.|::.||.:
Zfish   189 ELRILLLCGSDLLESFCIPGLWNESDMEVIVGDFGIVVVPRDGADTERIMNHSSVLRKHKDNIIV 253

  Fly   241 ITNWVPNE---VSSTLIRRLL--GRGQSVKYLLDDLVLEYIKRQRLF 282
            :.:.:.:.   ||||..|..|  |.|..|.| |...|::||.:.:|:
Zfish   254 VKDEIDHPMSIVSSTKSRLALQHGDGHVVDY-LSQPVIDYILQSQLY 299

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nmnat	NP_651315.2	NMNAT_Eukarya	46..282	CDD:185681	94/296 (32%)
nmnat2	NP_956298.1	NMNAT_Eukarya	9..299	CDD:185681	94/296 (32%)