DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Nmnat and nmat-2

DIOPT Version :9

Sequence 1:	NP_651315.2	Gene:	Nmnat / 42987	FlyBaseID:	FBgn0039254	Length:	389	Species:	Drosophila melanogaster
Sequence 2:	NP_492480.1	Gene:	nmat-2 / 172754	WormBaseID:	WBGene00009176	Length:	223	Species:	Caenorhabditis elegans

Alignment Length:	247	Identity:	85/247 - (34%)
Similarity:	127/247 - (51%)	Gaps:	34/247 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 LPRIAFIACGCFSPPTPMHLRMFEIAKDHFEMQGTHRVVGGIISPTHDSYGKK-GLASALDRCAM 106
            :.|:|.:|.|.|:|||..||||.|:|:.|.|...| :||.||:||..|||..| .|..:..|..|
Worm     1 MKRVALLAVGSFNPPTIAHLRMLEVARSHLETINT-QVVEGIMSPVADSYNNKPTLIKSNFRIQM 64

  Fly   107 VKLATQSSNWIRLSDWEVHQNQWMRTQAVLQHHQNYINNHINSGGGGGDDGENTHLPGWLPRGLH 171
            |:.||:||:|||..|||..:..|.||..||:||:..:.....|..|
Worm    65 VRAATKSSDWIRADDWECTRTTWTRTIDVLRHHRELVQEKFGSDVG------------------- 110

  Fly   172 DSRDPVHLKLLCGADLLESFA--VP---GLWAEADIEDIVANHGLVVITRAGSNPGKFIFDSDIL 231
                   :.|:.|.|:::||.  :|   .||..:||..|:...||:|::|.||||...|.....:
Worm   111 -------MMLVVGGDVVDSFTRILPDGSNLWNSSDIRTIITEFGLIVLSREGSNPLNTIQSMPAI 168

  Fly   232 TKYQSNITLITNWV-PNEVSSTLIRRLLGRGQSVKYLLDDLVLEYIKRQRLF 282
            :::...|..:.:.| |:.||||.:|..:...:|:||...|.|:.:|:...|:
Worm   169 SEFCDRIIQVKDEVCPSGVSSTRLRAAIMNKKSIKYSTPDEVINFIRENNLY 220

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nmnat	NP_651315.2	NMNAT_Eukarya	46..282	CDD:185681	83/242 (34%)
nmat-2	NP_492480.1	NMNAT_Eukarya	4..220	CDD:185681	83/242 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	116	1.000	Domainoid score	I3731
eggNOG	1	0.900	-	-		E1_COG1057
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H39772
Inparanoid	1	1.050	135	1.000	Inparanoid score	I3145
Isobase	1	0.950	-	0	Normalized mean entropy	S1288
OMA	1	1.010	-	-		QHG54406
OrthoDB	1	1.010	-	-		D1308027at2759
OrthoFinder	1	1.000	-	-		FOG0000967
OrthoInspector	1	1.000	-	-		otm14657
orthoMCL	1	0.900	-	-		OOG6_100907
Panther	1	1.100	-	-	LDO	PTHR12039
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R815
SonicParanoid	1	1.000	-	-		X704
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.820