DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ssh and Dusp18

DIOPT Version :9

Sequence 1:	NP_733063.1	Gene:	ssh / 42986	FlyBaseID:	FBgn0029157	Length:	1193	Species:	Drosophila melanogaster
Sequence 2:	NP_776106.1	Gene:	Dusp18 / 75219	MGIID:	1922469	Length:	188	Species:	Mus musculus

Alignment Length:	165	Identity:	47/165 - (28%)
Similarity:	75/165 - (45%)	Gaps:	10/165 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   386 TKIFEHVYLGSEWNASNLEELQKNGVRHILNVTREIDNFFPGTFEYFNVRVYDDEKTNLLKYWDD 450
            ::|.:.:::.:...|:|...|..|.:..::||:.|:.|.|....:|..|.|.|.....|..::|.
Mouse    21 SQITKSLFISNGVAANNKLLLSSNQITTVINVSVEVANTFYEDIQYVQVPVVDAPVARLSNFFDS 85

  Fly   451 TFRYITRAKAEGSKVLVHCKMGVSRSASVVIAYAMKAYQWEFQQALEHVKKRRSCIKPNKNFLNQ 515
            ....|...:.:..:.|:||..||||||::.:||.||.:......|....|..|..|:||..|..|
Mouse    86 VADRIHSVEMQKGRTLLHCAAGVSRSAALCLAYLMKYHAMSLVDAHTWTKSCRPIIRPNSGFWEQ 150

  Fly   516 LETYSGMLDAMKNKEKLQRS---------KSETNL 541
            |..|...|.. ||..::..|         :.||.|
Mouse   151 LIHYELQLFG-KNTMQMMDSPMGRIPDIYEKETRL 184

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ssh	NP_733063.1	SSH-N	21..313	CDD:212166
		DEK_C	328..379	CDD:285919
		DSPc	385..519	CDD:238073	39/132 (30%)
Dusp18	NP_776106.1	PTP_DSP_cys	19..176	CDD:391942	44/155 (28%)
Dusp18	NP_776106.1	Sufficient for mitochondrial localization	95..141		16/45 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1576308at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2281
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.950