Protein Alignment ssh and Dusp10

DIOPT Version :10

• Sequence 1: NP_733063.1
• Gene: ssh / 42986
• FlyBaseID: FBgn0029157
• Length: 1193
• Species: Drosophila melanogaster
• Sequence 2: NP_071302.2
• Gene: Dusp10 / 63953
• MGIID: 1927070
• Length: 483
• Species: Mus musculus
• Alignment Length: 507
• Identity: 120/507 - (23%)
• Similarity: 202/507 - (39%)
• Gaps: 98/507 - (19%)

  Fly    48 LVLALKDIPPLTQSERRLSTDSTRSSNSTQSNNSDIQLHLQSMFYLLQREDTLKMA---VKLESQ 109
            :|:||.  .|:...:..|..||:...:::..:.|...:       |.....|||.|   ....|.
Mouse    10 VVVALS--RPVRPQDLNLCLDSSYLGSASPGSGSHAPV-------LATAVVTLKAANLTYMPSSS 65

  Fly   110 RSNRTRYLVIASRSCCRSGTSDRRRHRIMRHHSVKVGGSAGTKSSTSPAVPTQRQLSVEQTATEA 174
            .|.|:.....:|.|||...|.|:      .|.:.....:|||.:                ||...
Mouse    66 GSARSLNCGCSSTSCCTVATYDK------DHQAQTQAIAAGTAT----------------TAIGT 108

  Fly   175 SSKCDKTADKENATAAGDNKNTSGMEESCLLGIDCNERTTIGLVVP------ILADTTIHLDGDG 233
            |:.|.......|....|...:.||...|.:.|.. .:..:|.::.|      :...:..||...|
Mouse   109 STTCPANQMVNNNENTGSVLSPSGGVGSPVSGTP-KQLASIKIIYPNDLAKKMTKCSKSHLPSQG 172

  Fly   234 GFSVKV-----YEKTHIFKPVSV---------QAMWSALQTLHKVSKKARENNFYASGPSHDWLS 284
            ...:..     |.|:||...|.:         :.....:..|..:|.:..:::|
Mouse   173 PVIIDCRPFMEYNKSHIQGAVHINCADKISRRRLQQGKITVLDLISCREGKDSF----------- 226

  Fly   285 SYERRIESDQSCLNEWNAMDALESRRPPS-PDAIRNKPPEKEETES-VIKMKLKAIMM------- 340
               :||.|.:..:.:.|..:  .||..|| |..|..:..::|..|. |:|..|.:...
Mouse   227 ---KRIFSKEIIVYDENTNE--PSRVTPSQPLHIVLESLKREGKEPLVLKGGLSSFKQNHGNLCD 286

  Fly   341 -SVDLDEVTSKYIRG---RLEEILDMDLGEYKSFIDAEMLVILGQMDAPTKIFEHVYLGSEWNAS 401
             |:.|.|  .:.:.|   ....:|...:.......:||:          |.|...::||:|.:|.
Mouse   287 NSLQLQE--CREVGGGASAASSMLPQSVPTTPDIENAEL----------TPILPFLFLGNEQDAQ 339

  Fly   402 NLEELQKNGVRHILNVTREID--NFFPGTFEYFNVRVYDDEKTNLLKYWDDTFRYITRAKAEGSK 464
            :|:.:|:..:.:::|||..:.  ::..|.|.|..:...|..|.||.:|:::.|.:|..|...|..
Mouse   340 DLDTMQRLNIGYVINVTTHLPLYHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGKG 404

  Fly   465 VLVHCKMGVSRSASVVIAYAMKAYQWEFQQALEHVKKRRSCIKPNKNFLNQL 516
            :|:||:.||||||::||||.||..:.....|.:.||.:|..|.||.||:.||
Mouse   405 LLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQL 456

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ssh	NP_733063.1	SSH-N	21..313	CDD:212166	55/287 (19%)
		DEK_C	326..379	CDD:462592	11/64 (17%)
		DSP_slingshot	385..523	CDD:350363	49/134 (37%)
Dusp10	NP_071302.2	DSP_MapKP	150..285	CDD:238723	27/150 (18%)
		Interaction with MAP kinases. /evidence=ECO:0000250	200..216		1/15 (7%)
		DSP_DUSP10	323..474	CDD:350415	49/144 (34%)