Protein Alignment ssh and ssh2b

DIOPT Version :10

• Sequence 1: NP_733063.1
• Gene: ssh / 42986
• FlyBaseID: FBgn0029157
• Length: 1193
• Species: Drosophila melanogaster
• Sequence 2: XP_009293925.1
• Gene: ssh2b / 557912
• ZFINID: ZDB-GENE-081205-4
• Length: 1179
• Species: Danio rerio
• Alignment Length: 1304
• Identity: 400/1304 - (30%)
• Similarity: 556/1304 - (42%)
• Gaps: 323/1304 - (24%)

  Fly    37 SECFFAGKGTALVLALKDIPPLTQSERRLSTDSTRSSNSTQSNNSDIQLHLQSMFYLLQREDTLK 101
            ||.|...||.||.|      |........|:.|:|.:.....:..|:|.|||:||.||:.||.::
Zfish    52 SESFLTVKGAALFL------PRGNGSSAASSCSSRITAQRSKHAGDLQQHLQTMFTLLRPEDNIR 110

  Fly   102 MAVKLESQRSNRTRYLVIASRSCCRSGTSDRRRHRIMRHHSVKVGGSAGTKSSTSPAVPTQRQLS 166
            :||:|||.....|||:|:.|    .:|..|
Zfish   111 LAVRLESTFPQCTRYMVVVS----TNGRQD----------------------------------- 136

  Fly   167 VEQTATEASSKCDKTADKENATAAGDNKNTSGMEESCLLGID---CNERTTIGLVVPILADTTIH 228
                                            .|||.:||:|   .:...:||:|:|:.:||.||
Zfish   137 --------------------------------TEESVVLGMDFSPSDSSCSIGMVLPLWSDTRIH 169

  Fly   229 LDGDGGFSVKVYEKTHIFKPVSVQAMWSALQTLHKVSKKARENNFYASGPSHDWLSSYERRIESD 293
            |||||||||....|.||||||||||||||||:|||..:.||.:|::.......|:|.|:.|:.||
Zfish   170 LDGDGGFSVSTDNKIHIFKPVSVQAMWSALQSLHKACEVARCHNYFPGSLFLTWVSYYQSRVSSD 234

  Fly   294 QSCLNEWNAMDALESRRPPSPDAIRNKPPEKEETESVIKMKLKAIMMSVDLDEVTSKYIRGRLEE 358
            |:.:||||||..::|.|..||....:.|.|:|.||..||.:|:.|||..||:.||||.||..||.
Zfish   235 QARINEWNAMQDVQSHRADSPVLFSDVPTERERTERFIKTRLREIMMLKDLENVTSKDIRTELEM 299

  Fly   359 ILDMDLGEYKSFIDAEMLVILGQMDAPTKIFEHVYLGSEWNASNLEELQKNGVRHILNVTREIDN 423
            .:..:|.|:|.:||.||:|||||||.|||||||||||||||||||||||..||::||||||||||
Zfish   300 QMVCNLREFKEYIDNEMIVILGQMDRPTKIFEHVYLGSEWNASNLEELQNTGVQYILNVTREIDN 364

  Fly   424 FFPGTFEYFNVRVYDDEKTNLLKYWDDTFRYITRAKAEGSKVLVHCKMGVSRSASVVIAYAMKAY 488
            ||||.|||.|:||||:|.|:||.||:||:::|:|||..|:|.|||||||||||||.|||||||.|
Zfish   365 FFPGLFEYHNIRVYDEEATDLLAYWNDTYKFISRAKKAGAKCLVHCKMGVSRSASTVIAYAMKEY 429

  Fly   489 QWEFQQALEHVKKRRSCIKPNKNFLNQLETYSGMLDAMKNK-EKLQRSKSETNL--------KST 544
            .|:.:||.|:||:||:..|||.:|:.||..|.|:|.|.|.: .||.||.|:::|        |:|
Zfish   430 GWDMEQAFEYVKERRAVTKPNPSFMRQLVEYQGILIASKQRHNKLWRSHSDSDLSERLEPLCKAT 494

  Fly   545 -------KDARLLPGSEPTPLIQALNQAKSKSTGEA-----GVTPDGEEEDGSRMHRRSIAQKSQ 597
                   ..:|.....:.:|.||.|.|..:.|:..|     .|.|:......|.:|..::.:.::
Zfish   495 AAQSLGRSSSRNQTFGQTSPSIQELLQTLTPSSATATGSNRPVEPNTTRWSDSHIHNGTLHEATE 559

  Fly   598 RRMVRRSSSTSPKTQTAVVTKQQSQSMENLTPERSVAEEPKNMRFPGSNGENYSVTQNQVLHIQK 662
                   :.:.|:.:.|.|..:....:.::|...:|:  |.....|.:           |||
Zfish   560 -------TLSFPRPRAATVVPEARPDITSVTVTETVS--PGRPHPPPA-----------VLH--- 601

  Fly   663 HTPLSVRTRIHDLEAHRADQLPQQPVWTSLTKLITQTSHLGKSVSGSSSGNIDSRRDSSCSDVFS 727
              |.|....:.|.:|.:.  ||:          ::....|.|| |.....:::.|....|:..
Zfish   602 --PPSSPKLLSDAKAKQG--LPE----------VSNLVPLEKS-SPKVHSSVNIRTPEPCTQA-- 649

  Fly   728 SQVDSVFAKDEGEKRQRRKT------HSWTESLGPSGGI---VLDPTP-------------QQQK 770
              :||...:|..::....:|      ||..|...||..:   .|.|||             .::|
Zfish   650 --LDSPGLQDLSQQVPNMETDCAGLSHSSDEDHHPSATLQRAELTPTPPSTLSIDRIDFFSAREK 712

  Fly   771 QQ--SNAILRPRGTRQ----------------RELPSRHASWGSGDNRCCLPQRTSSGSYYDSN- 816
            .|  |..|   |||.|                |.||.............|.....|..|..:|.
Zfish   713 FQGLSQEI---RGTDQVVGQAPRDKSPSVETKRLLPDNPIKEEEQKKESCSVSVHSKMSGVESTW 774

  Fly   817 RNTTAIFEGVIQDLKRSSN-----CNVI--EGVAVAVEPIVGVGEGTVKRTKQKLEESTSLKKRC 874
            .|.|.......|.:..||:     ..|:  |.....||......:|||.|..::||:     |..
Zfish   775 HNVTPSPPPTSQPVSSSSSEEEEFAQVMSAEAEMEKVEHGKDWPKGTVWRATRELEQ-----KIK 834

  Fly   875 QEESQELLLEAVDAGQRRCPSLYRSASSAHSPRQRQPLRCNSEELMHTSDIENKNTTPGDHEATV 939
            ||.|...|:.:...    ||       |..||.....:....|...||....:.||....|.
Zfish   835 QEVSSVALVSSAPV----CP-------SRRSPVNTSSMEKTEETSSHTHLTPDPNTVSTRHH--- 885

  Fly   940 VLRVQGQTLADDQRISGNVQILKQNFEAKAGVVGTGGGGGGGTAAGSGSSSTIATSVSAVAGACS 1004
              :.|...:..|:..|         ||                 .||.|...:........|...
Zfish   886 --QPQYHKVEKDRSFS---------FE-----------------EGSESERRLREGEHRNTGLTH 922

  Fly  1005 ANPGKKTTSHQSLPSSPVAQHANHVSAASNSNSS----------------------ASNSSDSSV 1047
            :   :::.||.|..|.|:......::...:...|                      .||.||..:
Zfish   923 S---RQSHSHSSSCSPPLVLQLEGITEQESYTDSRCPKDMRETWETLKELGAFLWQVSNCSDRRL 984

  Fly  1048 SENCDRNV--KGLVHKYQT--TTSCSSQAAATP--------------TVACAP-------LPPA- 1086
            |:...|..  ||...:.:|  ..:...||..||              ::..:|       |.||
Zfish   985 SQPWSRREQRKGRAARERTKEVEARIRQAGLTPPSKMKRSASLAKLGSLEISPIDLSELDLSPAL 1049

  Fly  1087 -GTASNISHSCSTTTTTSFKQR----------------PLSYYDRSLSNRSTHD-------YSDS 1127
             ...:|.....|.:..||.|||                |:|.....:...:.:|       |||:
Zfish  1050 LSAPTNKPRPNSYSDDTSKKQRVLPHCTPAPLPSSSASPVSSTGSPMLGHAENDDTTEEGEYSDN 1114

  Fly  1128 RPPPAPVRVSHSSNV---QHQQQQQQQLQPEQHQQQVQIRRLAQHGKTHPLSRLSAPKTGFNTAA 1189
            ...|.|:..|..||.   ....|::....|......:.:....|:|:||||.||.  |...|  .
Zfish  1115 DVMPMPLPHSPPSNQCWRGGNAQEEAGCAPLPASTLIPVATRQQYGRTHPLRRLK--KRTVN--P 1175

  Fly  1190 YNTM 1193
            |:||
Zfish  1176 YHTM 1179

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ssh	NP_733063.1	SSH-N	21..313	CDD:212166	96/278 (35%)
		DEK_C	326..379	CDD:462592	26/52 (50%)
		DSP_slingshot	385..523	CDD:350363	98/137 (72%)
ssh2b	XP_009293925.1	SSH-N	38..254	CDD:212166	96/278 (35%)
		DEK_C	262..320	CDD:462592	29/57 (51%)
		DSP_slingshot_2	323..466	CDD:350417	101/142 (71%)