Protein Alignment ssh and DUSP13B

DIOPT Version :10

• Sequence 1: NP_733063.1
• Gene: ssh / 42986
• FlyBaseID: FBgn0029157
• Length: 1193
• Species: Drosophila melanogaster
• Sequence 2: NP_001350443.1
• Gene: DUSP13B / 51207
• HGNCID: 19681
• Length: 334
• Species: Homo sapiens
• Alignment Length: 343
• Identity: 77/343 - (22%)
• Similarity: 135/343 - (39%)
• Gaps: 86/343 - (25%)

  Fly   215 IGLVVPILADTTIHLDGDGGFSVKVYEKTHIFKPV-SVQAMWS-----------ALQTLH----- 262
            :.|..|..:...:...|.|    ..|::..:|.|| :..:.||           ...|.|
Human    37 VSLAKPAASWVPVSFSGPG----TAYQREKMFFPVCTFPSHWSRGSGAVSKDRTPSPTRHQAHIL 97

  Fly   263 ---KVSKKARENNFYASGPSHDWLSSYERRIESDQSCLNEWNAMDALES---RRPPSPDAIR--- 318
               |:..:...::|....|.    :||..|:..|..|..|...||:|:.   |||....|::
Human    98 VPLKIQLRRVPDSFSQQMPE----TSYLTRVGPDIQCWPESWGMDSLQKQDLRRPKIHGAVQASP 158

  Fly   319 NKPPEKEETESVIKMKLKAIMMSVDLDEVTSKYIRGRLEEILDMDLGEYKSFIDAEMLVILGQMD 383
            .:||.....:.::.::..|.:..:|
Human   159 YQPPTLASLQRLLWVRQAATLNHID---------------------------------------- 183

  Fly   384 APTKIFEHVYLGSEWNASNLEELQKNGVRHILNVTR---EID---NFFPG-TFEYFNVRVYDDEK 441
               :::..::||..:.|.:..:|.:.|:.|::|...   ::|   .|:.| :.||:.:...|:..
Human   184 ---EVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDNPF 245

  Fly   442 TNLLKYWDDTFRYITRA-KAEGSKVLVHCKMGVSRSASVVIAYAMKAYQWEFQQALEHVKKRRSC 505
            .:|..|:....|||..| .....:|||||.|||||||::|:|:.|........:|::.|:..|:
Human   246 FDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQTVQAHRN- 309

  Fly   506 IKPNKNFLNQLETYSGML 523
            |.||..||.||:.....|
Human   310 ICPNSGFLRQLQVLDNRL 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ssh	NP_733063.1	SSH-N	21..313	CDD:212166	27/120 (23%)
		DEK_C	326..379	CDD:462592	2/52 (4%)
		DSP_slingshot	385..523	CDD:350363	44/145 (30%)
DUSP13B	NP_001350443.1	DUSP13B	164..327	CDD:350425	46/206 (22%)