Protein Alignment ssh and Styxl2

DIOPT Version :10

• Sequence 1: NP_733063.1
• Gene: ssh / 42986
• FlyBaseID: FBgn0029157
• Length: 1193
• Species: Drosophila melanogaster
• Sequence 2: NP_001178858.1
• Gene: Styxl2 / 498267
• RGDID: 1560598
• Length: 1137
• Species: Rattus norvegicus
• Alignment Length: 994
• Identity: 203/994 - (20%)
• Similarity: 361/994 - (36%)
• Gaps: 248/994 - (24%)

  Fly   291 ESDQSCLNEWNAMD--ALESR--RPPSP-------DAIRNKPPEKEETES--------------- 329
            |.:|...||.:..|  |:::.  |.|||       ||         ||||
  Rat     8 EEEQVVPNEEDEADVRAVQAHYLRSPSPSQYSVVSDA---------ETESIFMEPIHLSSAVAAK 63

  Fly   330 -VIKMKLK-----------AIMMSVDLDEVTSKYIRGRLEEILDMDLGEYKSFIDAEMLVILGQM 382
             :|..:||           .::.|.:...|...|.|.| |::.|..|......:|.:..:|..:.
  Rat    64 QIINEELKPRGLRTDTECPGMLESAEQLLVEDLYNRVR-EKMDDKSLFNTPCVLDLQRALIQDRQ 127

  Fly   383 DAP----TKIFEHVYLGSEWNASNLEELQKNGVRHILNVTREI-----DNFFPG-TFEYFNVRVY 437
            :||    .:::.:|::..:..|.|...|::.|:.||||.....     ..|:.| ..:|..|.|.
  Rat   128 EAPRNEVDEVWPNVFIAEKSVAVNKGRLKRLGITHILNAAHGTGVYTGPEFYTGLEIQYLGVEVD 192

  Fly   438 DDEKTNLLKYWDDTFRYITRA-KAEGSKVLVHCKMGVSRSASVVIAYAMKAYQWEFQQALEHVKK 501
            |..:.::.:::.....::..| .....||||..:||:||||.:|:||.|..:.....:||..|::
  Rat   193 DFPEVDISQHFRKAAEFLDEALLTYRGKVLVSSEMGISRSAVLVVAYLMIFHNMAILEALMTVRR 257

  Fly   502 RRSCIKPNKNFLNQLETYSGMLDAMKNKEKL--QRSKSETNLKSTKDARLLPGSEPTPLI----- 559
            :|: |.||..||.||...:         |||  :|.:.:...:..:||....|:....|:
  Rat   258 KRA-IYPNDGFLKQLRELN---------EKLMEEREEEDDEEEPEEDAGSTLGARVNSLMVEEED 312

  Fly   560 QALNQAKSKSTGEAG-----VTPDGEEEDGSRMHRRSIAQKSQRRMVRRSSSTSPKTQTAVVTKQ 619
            .|.:.....|.|:|.     ||...|||: .|::..   .:..:...:..:|...|...:..::|
  Rat   313 DATSHLSGSSLGKASQVSQPVTLIDEEEE-ERLYEE---WRKGQGFPKAEASQGRKGSCSASSEQ 373

  Fly   620 QSQSMENLTPERSVAE-EPKNMRFPGS-----NGENYSVTQNQVLHIQKHTPLSVRTRIHDLEAH 678
            .....|:...||.:.| :.:|.|:...     |.|.....:|.....::...||..:....:.:|
  Rat   374 DGDDCEDGAVERIIQEWQSRNERYQAKGHKQWNREEDEEEENSYTSRRRRHTLSESSASESVSSH 438

  Fly   679 RADQLPQQPVWTSLTKLITQTSHLGKSVSGSSSGNIDSRRDSSCSDVFSSQVDSVFAKDEGEKRQ 743
            ....|.||      .|..:|:.|        .....||....|..|:::.::..:      ||..
  Rat   439 DIRVLKQQ------LKRTSQSRH--------DRHRSDSESTESTWDMWNERLVEI------EKEA 483

  Fly   744 RRKTHSWTESLGPSGGIVLDPTPQQQKQQSNAILRPRGTRQRELPSRHASWGSGDNRCCLPQRTS 808
            .||..|.::.             ::....|.|     |:|.||          .|....|.:.:|
  Rat   484 ARKYRSKSKR-------------EELDADSEA-----GSRVRE----------DDEESVLSEASS 520

  Fly   809 SGSYYDSNRN-TTAIFEGVIQDLK---RSSNCNVIEGVAVAVEPIVGVGEGTVKRTKQKLEESTS 869
            ..::...|:: .||:....::.::   ...:..|::         .|..:||.:.|.:|.....:
  Rat   521 FYNFCSRNKDKLTALERWKVKRIQFGFHKKDSEVVD---------AGSEDGTEEATGEKNLSDVN 576

  Fly   870 LKKRCQEESQELLLEAVDAGQRRCPSLYRSASSAHSPRQRQPLRCNSEELMHTSDIENKNTTPGD 934
            |                        :.|::....|   |::....|.||::..|..|:.......
  Rat   577 L------------------------TAYQAWKLKH---QKKVGNENKEEVVEMSKGEDTALAKKR 614

  Fly   935 HEATVVLRVQGQTLADDQRISGNVQILKQNFEAKAGVVGTGGGGGGGTAAGSGSSS---TIATSV 996
            .....:|....||| ::.|..|:.:                  |...||:.|...|   :.|.||
  Rat   615 QRRLELLERSRQTL-EESRSMGSWE------------------GDSSTASRSIPLSAFWSAAPSV 660

  Fly   997 SAVAGACSANPGKKTTSHQS----------LPSSPVAQHANHVSAASNSNSSASNSSDSSVSENC 1051
            |......|....:...||.|          ||:.||.. .:.:|.||..|..|     |.|:|..
  Rat   661 SVDGDTASVLSAQSQHSHLSQPASNMPTTPLPNLPVGP-GDTISIASIQNWIA-----SVVNETL 719

  Fly  1052 DRNVKGLVHKYQTTTSCSSQAAATPTVAC--------------APLPPAGTASNISHSCSTTTTT 1102
            .:....::...:..:..|.:||  |..:|              ..|||.......|...|..::|
  Rat   720 AQKQNEMLTLSRAPSVASMRAA--PAASCLGDDQLSVLSTSLSGCLPPQSQGRPSSDVQSVLSST 782

  Fly  1103 SFKQRPLSYYDRSLSNRSTHDYSDSRPPPAPVRVSHSSNVQ----HQQQQQQQLQPEQHQQQVQI 1163
            |           ||::|:....:..|....|:....:.||.    .:::::.|::.::...:.::
  Rat   783 S-----------SLTSRAEGSENKVRGTSKPIYSLFADNVNLKELGRKEKEMQMELQEKMSEYKM 836

  Fly  1164 RRLAQHGKTHPLSRLSAPK 1182
            .:||...|...|.:....|
  Rat   837 EKLASDNKRSSLFKKKKAK 855

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ssh	NP_733063.1	SSH-N	21..313	CDD:212166	7/25 (28%)
		DEK_C	326..379	CDD:462592	16/79 (20%)
		DSP_slingshot	385..523	CDD:350363	42/148 (28%)
Styxl2	NP_001178858.1	DSP_iDUSP27	124..279	CDD:350424	45/164 (27%)