DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ssh and dusp2

DIOPT Version :9

Sequence 1:	NP_733063.1	Gene:	ssh / 42986	FlyBaseID:	FBgn0029157	Length:	1193	Species:	Drosophila melanogaster
Sequence 2:	NP_001003451.1	Gene:	dusp2 / 445057	ZFINID:	ZDB-GENE-040801-188	Length:	333	Species:	Danio rerio

Alignment Length:	388	Identity:	93/388 - (23%)
Similarity:	157/388 - (40%)	Gaps:	99/388 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   191 GDNKNTSGME--------------ESCLLGIDCNERTTIGLVVPILADTTIHLDGDGGFSVKVYE 241
            ||....||.|              ..|:: :||.         |.|           |||
Zfish     4 GDPLEISGSELVQILRTPSELFASGGCIV-LDCR---------PFL-----------GFS----- 42

  Fly   242 KTHIFKPVSVQAMWSALQTLHKVSKKARENNFYASGPSHDWLSSYERRIESDQSCLNEWNAMDAL 306
            :.||.:..:|.  |:::  |.:.||        :|..|.:||       .:|:|.|.:....|.
Zfish    43 RAHILESRNVN--WNSM--LRRRSK--------SSVVSLEWL-------VADKSLLAQLRNGDF- 87

  Fly   307 ESRRPPSPDAIRNKPPEKEETESVIKMK---LKAIMMSVDLDEVTSK-----YIRGRLEEILDM- 362
                  ||..:.:     |.:.||..:|   |.::::|....||.|.     :::|..:....:
Zfish    88 ------SPVVVLD-----ENSRSVRDLKSESLASLLISALQSEVQSASTHICFLQGGFDGFFALY 141

  Fly   363 ----------------DLGEYKSFIDAEMLVILGQMDAPTKIFEHVYLGSEWNASNLEELQKNGV 411
                            .|.|.:..:......:..| ..|.:|...::|||..::|..|.|::||:
Zfish   142 PELCFTAPAVLCSNHSTLSEPEPVMSGRKTPLYDQ-GGPVEILPFLFLGSAHHSSRRETLERNGI 205

  Fly   412 RHILNVTREIDNFFPGTFEYFNVRVYDDEKTNLLKYWDDTFRYITRAKAEGSKVLVHCKMGVSRS 476
            ..:|||:....|.|....:|..::|.|....::...:.:...:|...|..|.:|||||:.|:|||
Zfish   206 TAVLNVSSSCPNLFEEELQYKTLKVEDSLAADIRVLFPEAIHFIDSIKEGGGRVLVHCQAGISRS 270

  Fly   477 ASVVIAYAMKAYQWEFQQALEHVKKRRSCIKPNKNFLNQLETYSGMLDAMKNKEKLQRSKSET 539
            |::.:||.:.|.:....:|.:.||:||..|.||..|:.||..:.  .|.:.....|:|..|.|
Zfish   271 ATICLAYLIHAQRVRLDEAFDFVKRRRQVISPNLAFMGQLLQFE--TDVLCPYSVLERESSGT 331

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ssh	NP_733063.1	SSH-N	21..313	CDD:212166	28/135 (21%)
		DEK_C	328..379	CDD:285919	11/75 (15%)
		DSPc	385..519	CDD:238073	45/133 (34%)
dusp2	NP_001003451.1	DSP_MapKP	8..145	CDD:238723	38/193 (20%)
dusp2	NP_001003451.1	DSPc	178..314	CDD:238073	45/135 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1576308at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920