DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ssh and Dupd1

DIOPT Version :9

Sequence 1:	NP_733063.1	Gene:	ssh / 42986	FlyBaseID:	FBgn0029157	Length:	1193	Species:	Drosophila melanogaster
Sequence 2:	XP_036014638.1	Gene:	Dupd1 / 435391	MGIID:	3647127	Length:	226	Species:	Mus musculus

Alignment Length:	233	Identity:	66/233 - (28%)
Similarity:	101/233 - (43%)	Gaps:	26/233 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   324 KEETESVIKMKLKAIMMSVDLDEVTSKYIRGRLEEILDMDLGEYKSF-----IDAEMLVILG--Q 381
            ||.|....||.......||....:.::.:..|.||      |:.:.:     .:.|.|...|  |
Mouse     3 KERTSLGSKMASGDTKTSVKHAHLCAERLSVREEE------GDAEDYCTPGAFELERLFWKGSPQ 61

  Fly   382 MDAPTKIFEHVYLGSEWNASNLEELQKNGVRHILNVTREIDNFFPG-------TFEYFNVRVYDD 439
            .....:::..:::|.|..|.:...|||.|..|:||......|...|       ..||..|...|.
Mouse    62 YTHVNEVWPRLHIGDEATALDRYGLQKAGFTHVLNAAHGRWNVDTGPDYYRDMAIEYHGVEADDV 126

  Fly   440 EKTNLLKYWDDTFRYITRA-KAEGSKVLVHCKMGVSRSASVVIAYAMKAYQWEFQQALEHVKKRR 503
            ...:|..::.....:|..| :.:.||:||||.||.||||::|:||.|.........|::.|.|.|
Mouse   127 PTFDLSIFFYSAAAFIDSALRDDHSKILVHCAMGRSRSATLVLAYLMIHKNMTLVDAIQQVAKNR 191

  Fly   504 SCIKPNKNFLNQLETYSGMLDAMKNKEKLQRSKSETNL 541
             |:.||:.||.||..    ||....|::.|....:::|
Mouse   192 -CVLPNRGFLKQLRE----LDKQLVKQRRQAGPGDSDL 224

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ssh	NP_733063.1	SSH-N	21..313	CDD:212166
		DEK_C	328..379	CDD:285919	10/55 (18%)
		DSPc	385..519	CDD:238073	46/141 (33%)
Dupd1	XP_036014638.1	DUPD1	55..214	CDD:350423	51/163 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1716
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1576308at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820