DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ssh and CG10089

DIOPT Version :9

Sequence 1:	NP_733063.1	Gene:	ssh / 42986	FlyBaseID:	FBgn0029157	Length:	1193	Species:	Drosophila melanogaster
Sequence 2:	NP_001261803.1	Gene:	CG10089 / 39517	FlyBaseID:	FBgn0036369	Length:	447	Species:	Drosophila melanogaster

Alignment Length:	452	Identity:	101/452 - (22%)
Similarity:	171/452 - (37%)	Gaps:	69/452 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   387 KIFEHVYLGSEWNASNLEELQKNGVRHILNVTREIDNFFPGTFEYFNVRVYDDEKTNLLKYWDDT 451
            |:...:|:|:..::.:..:|::..:.||:.:........|.. .|..|...|....||.:|:...
  Fly     7 KVLPGLYVGNYRDSKDHAQLERFKISHIIAIHDSPRRLLPDK-HYLCVMASDTPDQNLSQYFSVC 70

  Fly   452 FRYITRAKAEGSKVLVHCKMGVSRSASVVIAYAMKAYQWEFQQALEHVKKRRSCIKPNKNFLNQL 516
            ..:|..|:.....||:||..|:|||.:|.:||.|.|....:::||:.|:..|:...||..|.:||
  Fly    71 NDFIHAARLREGNVLIHCLAGMSRSVTVAVAYIMTATHLNWKEALKVVRAGRAVANPNAGFQSQL 135

  Fly   517 ETYSGMLDAMKNKEKLQR------SKSETNLKSTKDARLLPGSEPTPLIQ-------ALNQAKSK 568
            :.:    :..|..|:.:|      |.:...|..||.|..|...:  .|:|       ..::.:..
  Fly   136 QEF----EQFKLSEERRRLRERFPSSALEQLDRTKVATALDNYQ--ELLQNRDICEGNCSRGEKC 194

  Fly   569 STGEAGVTPD----GEEEDGSRMHRRSIAQKSQRR----------MVRRSSSTSPKTQTAVVTKQ 619
            .||...:.|.    ......:..|.|..||.|...          ...:|..||||.....:.:
  Fly   195 PTGVCNMDPTKGLFRRRPSNASTHSRLRAQSSNANASSSSLSVSSAAAQSCPTSPKNSPLPIVR- 258

  Fly   620 QSQSMENLTPERSVAEEPKNMRFPGS-----------NGENYSVTQNQVLHIQKHTPLSVRT--- 670
            :|...|.:..:..|.|:|.......:           ..|...:.|.|.|...:.:|..|.:
  Fly   259 RSVGNERIPEDEIVLEQPPTTSREAAEYAAAFEDARREQEQRQLQQQQQLSRSQRSPRPVNSSRE 323

  Fly   671 --RIHDLEAHRADQLPQQPVWTSLTKLITQTSHLGKSVSGSSSGNIDSRRDSSCSDVFSSQVDSV 733
              |:....:.|.....:......|.:..:..|..|.....|.:| :.:...|..|.|..|:||..
  Fly   324 APRVSSAGSRRESAAREGNGSAQLQRSASTVSGFGVRPRSSPAG-LHAYTGSVPSSVHGSRVDLR 387

  Fly   734 FAKDEGE------KRQRRKTHSWTESLGPSGGIVLDPTP---------QQQKQQSNAILRPR 780
            .| |:|.      ...|..|.|.:.|.|.|||.. .|:|         ...|:.::.:.:||
  Fly   388 DA-DKGSAIYLGCSAPRASTLSISSSRGSSGGSA-PPSPCHTPPASPRHGVKRSTSLVKKPR 447

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ssh	NP_733063.1	SSH-N	21..313	CDD:212166
		DEK_C	328..379	CDD:285919
		DSPc	385..519	CDD:238073	37/131 (28%)
CG10089	NP_001261803.1	DSPc	4..139	CDD:238073	37/136 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462484
Domainoid	1	1.000	44	1.000	Domainoid score	I728
eggNOG	1	0.900	-	-		E2759_KOG1716
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1576308at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.750