Protein Alignment ssh and Ssh3

DIOPT Version :10

• Sequence 1: NP_733063.1
• Gene: ssh / 42986
• FlyBaseID: FBgn0029157
• Length: 1193
• Species: Drosophila melanogaster
• Sequence 2: XP_038941428.1
• Gene: Ssh3 / 365396
• RGDID: 1308679
• Length: 681
• Species: Rattus norvegicus
• Alignment Length: 676
• Identity: 231/676 - (34%)
• Similarity: 325/676 - (48%)
• Gaps: 162/676 - (23%)

  Fly    18 TPRDGESEDDEGNSKGNDR---SECFFAGKGTALVL---------ALKDIPPLTQ--SERRLSTD 68
            |||........|.|....|   ::.|...:|..|.|         |..|..|:.:  .|.:.:.|
  Rat    36 TPRPDPCSSGTGPSDKTQRPAPTQSFAVLRGAVLGLQDGGEGNDAAEADPEPMEKPSGEEQPAED 100

  Fly    69 STRSSNSTQSNNSDIQ-LHLQSMFYLLQREDTLKMAVKLESQRSNRTRYLVIASRSCCRSGTSDR 132
            .|.:...:||....:| .||..|..||:.:|.:::|.:||:.|..|.|||::.|..   .|.|:
  Rat   101 QTDNGQGSQSPWKQVQKRHLHLMVELLRPQDDIRLAAQLEAARPPRLRYLLVVSTG---EGLSE- 161

  Fly   133 RRHRIMRHHSVKVGGSAGTKSSTSPAVPTQRQLSVEQTATEASSKCDKTADKENATAAGDNKNTS 197
                                                                             
  Rat   162 ----------------------------------------------------------------- 161

  Fly   198 GMEESCLLGID----CNERTTIGLVVPILADTTIHLDGDGGFSVKVYEKTHIFKPVSVQAMWSAL 258
              ||:.|||:|    .:...|:|||:|:.:||.::|||||||||....::.||||||:|.||:.|
  Rat   162 --EETILLGVDFPDSSSHSCTLGLVLPLWSDTQVYLDGDGGFSVTSGGQSRIFKPVSIQTMWATL 224

  Fly   259 QTLHKVSKKARENNFYASGPSHDWLSSYERRIESDQSCLNEWNAMDALESRRPPSPDAIRNKP-- 321
            |.||:..:.|..:.....|.:..|.:.|:.::.|||.|||||.||..|||.|||:.:..::.|
  Rat   225 QVLHQACEVALGSGLVPGGSALAWATHYQEKLNSDQGCLNEWMAMSDLESFRPPNAEPGQSVPGW 289

  Fly   322 --PEKEETESVIKMKLKAIMMSVDLDEVTSKYIRGRLEEILDMDLGEYKSFIDAEMLVILGQMDA 384
              .|:|:.|..|..:|..::.:.|||.||||.||..||..|...|.:|:.|||.:||:::.|.|.
  Rat   290 GASEQEQMEQAILAELWQVLDASDLDSVTSKEIRQALELRLGCPLQQYRDFIDNQMLLLMAQQDR 354

  Fly   385 PTKIFEHVYLGSEWNASNLEELQKNGVRHILNVTREIDNFFPGTFEYFNVRVYDDEKTNLLKYWD 449
            .::||.|:||||||||:||||||:|.|.||||:.||||||||..|.|.||||:|:|...||.:|.
  Rat   355 ASRIFPHLYLGSEWNAANLEELQRNRVSHILNMAREIDNFFPERFTYHNVRVWDEESAQLLPHWK 419

  Fly   450 DTFRYITRAKAEGSKVLVHCKMGVSRSASVVIAYAMKAYQWEFQQALEHVKKRRSCIKPNKNFLN 514
            :|.|:|..|:|:|::|||||||||||||:.|:|||||.|.|..:|||.||::.|..::||..||.
  Rat   420 ETHRFIEDARAQGTRVLVHCKMGVSRSAATVLAYAMKQYGWGLEQALIHVQELRPIVRPNPGFLR 484

  Fly   515 QLETYSGMLDA-------------------------------------------MKNKEKLQRSK 536
            ||:||.|:|.|                                           |..|...:..|
  Rat   485 QLQTYQGILTASRQSHVWEQKVGVVSPEEPLAPEVSTPLPPLPPEPGGSGEGMVMGQKGSQETPK 549

  Fly   537 SETNLKSTKDAR--------LLPGSEPTPLIQALNQAKSKSTGEAGVTPDGEEEDGSRMH---RR 590
            .|..|:...:.|        |.|.|||            :||.|||..|:....|...:|   :.
  Rat   550 EELGLRPRINLRGVMRSISLLEPSSEP------------ESTTEAGDLPEVFSSDEEPLHPFSQL 602

  Fly   591 SIAQKSQRRMVRRSSSTSPKTQTAVV 616
            |.|:..||  |.:....:.|::.:||
  Rat   603 SRAKGGQR--VCKGPWPALKSRQSVV 626

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ssh	NP_733063.1	SSH-N	21..313	CDD:212166	87/310 (28%)
		DEK_C	326..379	CDD:462592	22/52 (42%)
		DSP_slingshot	385..523	CDD:350363	84/137 (61%)
Ssh3	XP_038941428.1	SSH-N	32..279	CDD:212166	90/313 (29%)
		DEK_C	298..349	CDD:462592	22/50 (44%)
		DSP_slingshot_3	352..495	CDD:350419	86/142 (61%)