DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ssh and Dusp15

DIOPT Version :9

Sequence 1:	NP_733063.1	Gene:	ssh / 42986	FlyBaseID:	FBgn0029157	Length:	1193	Species:	Drosophila melanogaster
Sequence 2:	NP_001102068.2	Gene:	Dusp15 / 362238	RGDID:	1305990	Length:	244	Species:	Rattus norvegicus

Alignment Length:	231	Identity:	61/231 - (26%)
Similarity:	99/231 - (42%)	Gaps:	27/231 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   386 TKIFEHVYLGSEWNASNLEELQKNGVRHILNVTREIDNFFPGTFEYFNVRVYDDEKTNLLKYWDD 450
            ||:...:|||:..:|.:.::|.:|.:.||::: .|..........|..:.|.|..:..:.|::.:
  Rat     6 TKVLPGLYLGNFIDAKDPDQLGRNKITHIVSI-HESPQPLLQDITYLRISVSDTPEVPIKKHFKE 69

  Fly   451 TFRYITRAKAEGSKVLVHCK--------MGVSRSASVVIAYAMKAYQWEFQQALEHVKKRRSCIK 507
            ...:|...:..|...||||.        .|:|||.:|||||.|......:|:.||.:|..|....
  Rat    70 CVHFIHSCRLNGGNCLVHCLSFTSGSFFAGISRSTTVVIAYVMTVTGLGWQEVLEAIKASRPIAN 134

  Fly   508 PNKNFLNQLETYSGMLDAMKNKEKLQRSKSETNLKSTKDARLLPGSEPTPLIQALNQAKSKSTGE 572
            ||..|..|||.: |..::.|.:.:|:....|...:..:|.|.|     .||.:...|....|...
  Rat   135 PNPGFRQQLEEF-GWANSQKLRRQLEERFGEIPFRDEEDLRAL-----LPLCRRCRQGPGTSAPS 193

  Fly   573 AGVTPDGEEEDGSRMHRRSIAQKSQRRMVRRSSSTS 608
            | .|......:|           :.:|:|.||...|
  Rat   194 A-TTASSAASEG-----------TLQRLVPRSPRES 217

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ssh	NP_733063.1	SSH-N	21..313	CDD:212166
		DEK_C	328..379	CDD:285919
		DSPc	385..519	CDD:238073	42/140 (30%)
Dusp15	NP_001102068.2	DSPc	4..146	CDD:238073	42/140 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1716
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1576308at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820