Protein Alignment ssh and Ssh1

DIOPT Version :9

• Sequence 1: NP_733063.1
• Gene: ssh / 42986
• FlyBaseID: FBgn0029157
• Length: 1193
• Species: Drosophila melanogaster
• Sequence 2: XP_038946124.1
• Gene: Ssh1 / 304580
• RGDID: 1306038
• Length: 1040
• Species: Rattus norvegicus
• Alignment Length: 1222
• Identity: 370/1222 - (30%)
• Similarity: 516/1222 - (42%)
• Gaps: 330/1222 - (27%)

  Fly    23 ESEDDEGNSKGNDRSECFFAGKGTALVLALKDIPPLTQSERRLSTDSTRSSNSTQSNNSDIQLHL 87
            |:..||........||.||..||.||.|           ::..|....||......:..|:..||
  Rat    25 EAGSDEDRKLNLSLSESFFMVKGAALFL-----------QQGNSPQGQRSLQHPHKHAGDLPQHL 78

  Fly    88 QSMFYLLQREDTLKMAVKLESQRSNRTRYLVIASRSCCRSGTSDRRRHRIMRHHSVKVGGSAGTK 152
            |.|..||:.||.:|:||:|||..::|.||:|:.    ..||..|
  Rat    79 QVMINLLRCEDRIKLAVRLESVWTDRVRYMVVV----YTSGRQD--------------------- 118

  Fly   153 SSTSPAVPTQRQLSVEQTATEASSKCDKTADKENATAAGDNKNTSGMEESCLLGIDCNER----T 213
                                                          .||:.|||:|.:.:    .
  Rat   119 ----------------------------------------------TEENILLGVDFSSKESKSC 137

  Fly   214 TIGLVVPILADTTIHLDGDGGFSVKVYEKTHIFKPVSVQAMWSALQTLHKVSKKARENNFYASGP 278
            |||:|:.:.:||.|||||||||||....:.||||||||||||||||.|||..:.||.:|::..|.
  Rat   138 TIGMVLRLWSDTKIHLDGDGGFSVSTAGRMHIFKPVSVQAMWSALQVLHKACEVARRHNYFPGGV 202

  Fly   279 SHDWLSSYERRIESDQSCLNEWNAMDALESRRPPSPDAIRNKPPEKEETESVIKMKLKAIMMSVD 343
            :..|.:.||..|.|:|||:||||||..|||.||.||....:||.|.|.||.:||.||::||||.|
  Rat   203 ALIWATYYESCISSEQSCINEWNAMQDLESTRPDSPALFVDKPTEGERTERLIKAKLRSIMMSQD 267

  Fly   344 LDEVTSKYIRGRLEEILDMDLGEYKSFIDAEMLVILGQMDAPTKIFEHVYLGSEWNASNLEELQK 408
            |:.||||.||..||:.::.:|.|:|.|||.|||:||||||.|:.||:|:|||||||||||||||.
  Rat   268 LENVTSKEIRNELEKQMNCNLKEFKEFIDNEMLLILGQMDKPSLIFDHLYLGSEWNASNLEELQG 332

  Fly   409 NGVRHILNVTREIDNFFPGTFEYFNVRVYDDEKTNLLKYWDDTFRYITRAKAEGSKVLVHCKMGV 473
            :||.:||||||||||||||.|.|.|:||||:|.|:||.:|::.:::|.:||...||.||||||||
  Rat   333 SGVDYILNVTREIDNFFPGLFAYHNIRVYDEETTDLLAHWNEAYQFINKAKRNHSKCLVHCKMGV 397

  Fly   474 SRSASVVIAYAMKAYQWEFQQALEHVKKRRSCIKPNKNFLNQLETYSGMLDAMKNK-EKLQRSKS 537
            |||||.|||||||.:.|..::|..:||::||..:||..|:.||..|.|:|||.|.: .||.|.:.
  Rat   398 SRSASTVIAYAMKEFGWPLEKAFNYVKQKRSITRPNAGFMRQLSEYEGILDASKQRHNKLWRQQP 462

  Fly   538 --------------------ETNLKSTKDA------RLLPGSEPT----------PLIQALNQAK 566
                                :|.|...:||      |.||...|:          ||:
  Rat   463 ADDTIAEPSEFLPETLDGALDTQLPCLEDATHPGLPRSLPSGGPSLPCCFRRLSDPLL------- 520

  Fly   567 SKSTGEAGVTP--DGEEEDGSRMHRRSIAQKSQRRMVRRSSSTSPKTQTAVVTKQQSQSMENLTP 629
                     .|  ||.   |..:|...:         .|.:....:.|...|.|....|.|.
  Rat   521 ---------LPHRDGA---GGLVHLEDL---------ERDALLEDEAQPVEVRKLVPSSQEG--- 561

  Fly   630 ERSVAEEPK-NMRFPGSNGENYSVTQNQVLHIQKHTPLSVRTRIHDLEAHRADQLPQQPVW---- 689
            :|...::.| .:.|......:.|:.|                 :.:||   .|..|:...|
  Rat   562 DRLCEKDVKRKLEFGSPKARSGSLPQ-----------------VEELE---KDGSPRPGRWRRAS 606

  Fly   690 TSLTKLITQTSHLGKSVSGSSSGNIDSRRDSSCSDVFSSQVDSVFAKDEGEKRQRRKTH-SWTES 753
            |.|.:.:....:|         .|.:|:|  ||.|.|  :.|:||    |...:.:..: |..:.
  Rat   607 TQLERGLLDQENL---------NNNNSKR--SCPDDF--ERDAVF----GILSKVKPPYTSCADC 654

  Fly   754 LGPSGGIVLDPTPQQQKQQSNAI-----LRPRGTRQRELPSRHASWGSGDNRCCLPQRTSSGSYY 813
            :.|:.|.......:.:...|:||     ..|..|..   |..|.|     ||...|:|.:||
  Rat   655 MYPAAGAPEAFMERHEDPSSSAICTQPTFLPHVTSS---PMAHTS-----NRSRAPERPTSG--- 708

  Fly   814 DSNRNTTAIFEGVIQ-DLKRSSNCNVIEGVAVAVEPIVGVGEGTVKRTKQKLEESTSLK------ 871
            .:|.:...:..|..: |:..|       |..||.||...:.|.: :.|.:.|::|...|
  Rat   709 PANTSPFLLPAGSRKPDVSGS-------GAGVAPEPPASLPEPS-RETSKALQKSLLSKNSHCDK 765

  Fly   872 ---------------KRCQEESQELLLEAVDAGQRRCPSLYRSASSAHSPRQRQPLRCNSEELM- 920
                           |:..:.|::|.|.....|::      .:|:|.....|...::.....|:
  Rat   766 NAANTEAAAKEELSTKKDPKPSKDLRLLFSQEGEK------PTANSYLMQHQESIIQLQKAGLVR 824

  Fly   921 -HTSDIENKNTTPGDHEAT----VVLRVQGQTLADDQRISGNVQILKQNFEAKAGVVGTGGGGGG 980
             ||.::|...:.|.|..:|    ...|::.....:.|.
  Rat   825 KHTKELERLKSLPSDSPSTCRDSAASRLEASIPEEGQE--------------------------- 862

  Fly   981 GTAAGSGSSSTIATSVSAVAGACSANP----------GKKTTSHQSLPSSPVAQHANHVSAASNS 1035
              .|.....|...|....|.||...:|          ..|..|...|.|:......:.:|    |
  Rat   863 --PAHPALDSQAGTEEKPVGGASQKSPPPTLLLRLDHTSKDFSKDFLKSACYTPTPSSIS----S 921

  Fly  1036 NSSASNSSDSSVSENCDRNVKGLVHKYQTTTSCSSQAAATPTVACAPLPPAGTASNISHSCSTTT 1100
            |.:.|:||||..|.   |...|||.  |......::.........:||       ..|||.:...
  Rat   922 NLTRSSSSDSIHSV---RGKPGLVK--QRAQEIETRLRLAGLTVSSPL-------KRSHSLAKLG 974

  Fly  1101 TTSFKQRPLSYYDRSLSNRSTHDYSDSR------------PPPAPVRVSHSS 1140
            :.:|....||      |...|...:||:            |..||...|.:|
  Rat   975 SLNFSTEDLS------SEADTSTIADSQDAKCTLSSFLPEPQAAPRNPSATS 1020

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ssh	NP_733063.1	SSH-N	21..313	CDD:212166	102/293 (35%)
		DEK_C	328..379	CDD:285919	28/50 (56%)
		DSPc	385..519	CDD:238073	83/133 (62%)
Ssh1	XP_038946124.1	SSH-N	3..237	CDD:212166	102/293 (35%)
		DEK_C	251..303	CDD:400903	29/51 (57%)
		PTP_DSP_cys	306..449	CDD:421693	88/142 (62%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	198	1.000	Domainoid score	I2987
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1576308at2759
OrthoFinder	1	1.000	-	-		FOG0002581
OrthoInspector	1	1.000	-	-		otm46075
orthoMCL	1	0.900	-	-		OOG6_104189
Panther	1	1.100	-	-	LDO	PTHR45864
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2719
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.920