Protein Alignment ssh and Ssh2

DIOPT Version :10

• Sequence 1: NP_733063.1
• Gene: ssh / 42986
• FlyBaseID: FBgn0029157
• Length: 1193
• Species: Drosophila melanogaster
• Sequence 2: XP_038941949.1
• Gene: Ssh2 / 303342
• RGDID: 1309389
• Length: 1450
• Species: Rattus norvegicus
• Alignment Length: 1288
• Identity: 402/1288 - (31%)
• Similarity: 558/1288 - (43%)
• Gaps: 314/1288 - (24%)

  Fly    21 DGESEDDEGNSKGNDRSECFFAGKGTALVLALKDIPPLTQSERRLSTDSTRSSNSTQSNNSDIQL 85
            :.:|.::|..|:....||.|...||.||.|           .|...:.:.|.|:....:..|:|.
  Rat    49 EADSGEEECRSQPRSISESFLTVKGAALFL-----------PRGNGSSTPRISHRRNKHAGDLQQ 102

  Fly    86 HLQSMFYLLQREDTLKMAVKLESQRSNRTRYLVIASRSCCRSGTSDRRRHRIMRHHSVKVGGSAG 150
            |||:||.||:.||.:::||:|||...|||||:|:.|    .:|..|
  Rat   103 HLQAMFILLRPEDNIRLAVRLESTYQNRTRYMVVVS----TNGRQD------------------- 144

  Fly   151 TKSSTSPAVPTQRQLSVEQTATEASSKCDKTADKENATAAGDNKNTSGMEESCLLGIDCNER--- 212
                                                            .|||.:||:|.:..
  Rat   145 ------------------------------------------------TEESIVLGMDFSSNDSS 161

  Fly   213 -TTIGLVVPILADTTIHLDGDGGFSVKVYEKTHIFKPVSVQAMWSALQTLHKVSKKARENNFYAS 276
             .|:|||:|:.:||.|||||||||||....:.||||||||||||||||:|||..:.||.:|:|..
  Rat   162 TCTMGLVLPLWSDTLIHLDGDGGFSVSTDNRVHIFKPVSVQAMWSALQSLHKACEVARMHNYYPG 226

  Fly   277 GPSHDWLSSYERRIESDQSCLNEWNAMDALESRRPPSPDAIRNKPPEKEETESVIKMKLKAIMMS 341
            .....|:|.||..|.||||.:||||||..::|.||.||....:.|.|:|.||.:||.||:.|||.
  Rat   227 SLFLTWVSYYESHINSDQSSVNEWNAMQDVQSHRPDSPALFTDIPTERERTERLIKTKLREIMMQ 291

  Fly   342 VDLDEVTSKYIRGRLEEILDMDLGEYKSFIDAEMLVILGQMDAPTKIFEHVYLGSEWNASNLEEL 406
            .||:.:|||.||..||..:..:|.|:|.|||.||:|||||||:||:|||||:|||||||||||:|
  Rat   292 KDLENITSKEIRTELEMQMVCNLREFKEFIDNEMIVILGQMDSPTQIFEHVFLGSEWNASNLEDL 356

  Fly   407 QKNGVRHILNVTREIDNFFPGTFEYFNVRVYDDEKTNLLKYWDDTFRYITRAKAEGSKVLVHCKM 471
            |..|||:||||||||||||||.|||.|:||||:|.|:||.||:||:::|::||..|||.||||||
  Rat   357 QNRGVRYILNVTREIDNFFPGVFEYHNIRVYDEEATDLLAYWNDTYKFISKAKKHGSKCLVHCKM 421

  Fly   472 GVSRSASVVIAYAMKAYQWEFQQALEHVKKRRSCIKPNKNFLNQLETYSGMLDAMKNK-EKLQRS 535
            |||||||.|||||||.|.|...:|.|:||:||:..|||.:|:.|||.|.|:|.|.|.: .||.||
  Rat   422 GVSRSASTVIAYAMKEYGWNLDRAYEYVKERRTVTKPNPSFMRQLEEYQGILLASKQRHNKLWRS 486

  Fly   536 KSETNLKSTKDARLLPG-----SEPTPLIQALNQAKSKSTGEA-------GVTPDGEEEDGSRMH 588
            .|:::|....:....||     .|.|.....:.:.|:..:..|       .|.|....:.|.|..
  Rat   487 HSDSDLSDHHEPICKPGLELNKKEMTTSADQITEVKTVESLAAMPPVFMEHVVPQDVNQKGLRTK 551

  Fly   589 RRSI-----AQKSQRRMVR----------------RSSSTSP----KTQTAVVTKQQSQSMENLT 628
            .|.|     :|:.....:.                .|.|..|    ....|::...|:..:.|..
  Rat   552 ERVICLEFSSQEFHAGQIEDELNLNDINGCSSGCCLSESKFPLDNCHASKALLQPGQAPDIANKF 616

  Fly   629 PERSVAEEPKNMRFPGSNGENYSVTQNQVLHIQKHTPLSVRTRIHDLE----AHRADQLPQQPVW 689
            |:.:|.:                         .:...|....|:|.|.    ..|...||..|
  Rat   617 PDLAVED-------------------------LETDALKADVRVHLLPMEELTSRLKDLPMSP-- 654

  Fly   690 TSLTKLITQTSHLG--KSVSGSSSGNIDSRRDSSCSDVFSSQVDSVFAKDEGEKRQRRKTHSWTE 752
                .|.:.:...|  .::|..|:..||          |.|.::. |.:...|.|.|..:||..|
  Rat   655 ----DLESPSPQAGCQAAISDFSTDRID----------FFSALEK-FVELSQETRSRSFSHSRIE 704

  Fly   753 SLGPSGGIVLDPTPQQQKQQSNAILRPRGTRQRELPSRHASWGSGDNRCCLPQRT---SSGSYYD 814
            .||  ||                  |..|.|...:....:...:.|.|......|   |..|..|
  Rat   705 ELG--GG------------------RSEGCRLSVMEMAPSEMVTDDQRSSSLSDTPHASEESSVD 749

  Fly   815 SNRNTTAIFEGVIQDL---KRSSNCNVIEGVAVAVEPI-VGVGEGTVKRTKQKLEESTSLKKRCQ 875
            .:: ..|:.|.|..|:   ..|.|...::.:...:|.| .|||:..:|        ...|...|.
  Rat   750 EDQ-PKAVSELVSPDIIMQSHSENAISVKEIVTEIESISQGVGQVQLK--------GDILSNPCH 805

  Fly   876 EESQ----ELLLEAVDAGQRRCPSLYRSAS--SAHSPRQRQPLRCNSEE-----LMHTSDIENKN 929
            ...:    ||.||.|...:.:...|.:..|  |......|...:|..||     |..|.|:|.:.
  Rat   806 TPKKNIIHELPLERVQGPENKPGHLEQDESFCSVQLELARDSGKCAPEEGCLATLSSTGDLEEEE 870

  Fly   930 TTPGDHE---------ATVVLRVQGQTLADDQRISGNVQILKQNFEAKAGVVGTGGGGGGGTAA- 984
            ...|:|:         ......|:..||..::|       |:|..|      ..|....|.|.:
  Rat   871 PVEGEHDWGPGTHPGAKWCPGSVRRATLEFEER-------LRQEQE------NHGTASPGPTLSN 922

  Fly   985 --GSGSSSTIA----------TSVSAVAGACSANPGK---KTTSHQSLPSSPVAQHANHVSAASN 1034
              .|.:.|::|          |:.........|.|||   |.:..::.|.|    |..|..||:.
  Rat   923 RKNSKNDSSVADLMPKWKSDETASEHSLSPKEAEPGKGKGKCSGSEAGPLS----HCEHNPAAAA 983

  Fly  1035 SNSSASNSS----DSSVSENCDRNVKGLVHKYQTTTS---CSSQAAATPTVACAPLPP------- 1085
            ......:.|    |...||:.....:..:.|.:|..|   |.:||      |..|||.
  Rat   984 PQLLEHHPSPAPQDCLGSESRSEKQEEDLRKQRTVVSNQECETQA------ALLPLPKKIEIIEY 1042

  Fly  1086 AGTASNISHSCSTTTTTSFKQ------RPLSYYDRSLSNRSTHDYSDSRP-PPAPVRVSHSSNVQ 1143
            ..|.:::.|:.....||..|:      |.:. .:||::...|.|.:.:|. .|:.|.:
  Rat  1043 TPTVTSLDHTEPGGETTPSKESEKQELRKVK-MERSITMFCTLDENLNRTLDPSQVSL------- 1099

  Fly  1144 HQQQQQQQLQPEQHQQQVQIRRLAQHGKTHPLSRLSAPK-------TGFNTAA 1189
                 :.|:.|..|... :..||     |.|...||:|:       |.|.|.|
  Rat  1100 -----RPQVLPLPHSSS-EYDRL-----TDPTPMLSSPQDKGDSPSTPFKTPA 1141

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ssh	NP_733063.1	SSH-N	21..313	CDD:212166	104/295 (35%)
		DEK_C	326..379	CDD:462592	27/52 (52%)
		DSP_slingshot	385..523	CDD:350363	96/137 (70%)
Ssh2	XP_038941949.1	SSH-N	38..263	CDD:212166	104/295 (35%)
		DEK_C	277..329	CDD:462592	27/51 (53%)
		DSP_slingshot_2	332..475	CDD:350417	99/142 (70%)