DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ssh and pmp1

DIOPT Version :9

Sequence 1:	NP_733063.1	Gene:	ssh / 42986	FlyBaseID:	FBgn0029157	Length:	1193	Species:	Drosophila melanogaster
Sequence 2:	NP_595205.1	Gene:	pmp1 / 2540019	PomBaseID:	SPBC1685.01	Length:	278	Species:	Schizosaccharomyces pombe

Alignment Length:	191	Identity:	54/191 - (28%)
Similarity:	84/191 - (43%)	Gaps:	45/191 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   414 ILNVTREIDNFFPGTFEYFNVRVYDDEKTNL-------LKY----WDDTFRYIT----------- 456
            ::||.:|:.:.|     ..:.|.|.|.|.||       ::|    ||...::..
pombe    86 VINVAKEVLHPF-----RTDGRHYRDSKHNLDIQVFDHIEYVHIHWDHDTQFALELDKLVSFVAY 145

  Fly   457 RAKAEGSKVLVHCKMGVSRSASVVIAYAMKAYQWEFQQALEHVKKRRSCIKPNKNFLNQLETYSG 521
            .|.....|||::|:||:||||.::||:.||........|.|:||:|...|.||.:.:.||..|..
pombe   146 NAMQLNKKVLINCQMGISRSACLMIAFIMKTLNLNVSDAYEYVKERSPWIGPNMSLIFQLSEYQQ 210

  Fly   522 MLDAMKNKEKLQRSKSETNLKSTK---DARLL----PGSEPTPLIQALNQAKSKSTGEAGV 575
            ::    .|...|.....::||.:|   :..||    |.|...||:       |.||.|:.:
pombe   211 II----RKNSSQGPYQSSSLKQSKRKSEGNLLFPEKPHSAQLPLV-------SPSTSESSM 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ssh	NP_733063.1	SSH-N	21..313	CDD:212166
		DEK_C	328..379	CDD:285919
		DSPc	385..519	CDD:238073	38/126 (30%)
pmp1	NP_595205.1	CDC14	35..227	CDD:225297	41/149 (28%)
pmp1	NP_595205.1	DSPc	61..209	CDD:238073	38/127 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1716
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2281
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840