Protein Alignment ssh and DUSP4

DIOPT Version :10

• Sequence 1: NP_733063.1
• Gene: ssh / 42986
• FlyBaseID: FBgn0029157
• Length: 1193
• Species: Drosophila melanogaster
• Sequence 2: NP_001385.1
• Gene: DUSP4 / 1846
• HGNCID: 3070
• Length: 394
• Species: Homo sapiens
• Alignment Length: 365
• Identity: 87/365 - (23%)
• Similarity: 152/365 - (41%)
• Gaps: 93/365 - (25%)

  Fly   185 ENATAAG--DNKNTSGMEE--SCLLGIDCNERTTIGLVVPILADTTIHLDGDGGFSVKVYEKTHI 245
            ||...||  .:..|.|:..  .||| :||.         |.||.:..::.|    ||.|...|.:
Human    23 ENGGGAGGSGSHGTLGLPSGGKCLL-LDCR---------PFLAHSAGYILG----SVNVRCNTIV 73

  Fly   246 FK----PVSVQAMWSALQTLHKVSKKAR-ENNFYASGPSHDWLSSYERRIESDQSCLNEWNAMDA 305
            .:    .||::.:..|.:.:     :|| .:..|::...:|
Human    74 RRRAKGSVSLEQILPAEEEV-----RARLRSGLYSAVIVYD------------------------ 109

  Fly   306 LESRRPPSPDAIRNKPPEKEETESVIKMKLKAIMMSVDLDEVTSKYIRGRLEEILDMDLGEYKSF 370
               .|.|..:::|.        :|.:.:.::|:..:.:..::.  .::|..|..    ..||..|
Human   110 ---ERSPRAESLRE--------DSTVSLVVQALRRNAERTDIC--LLKGGYERF----SSEYPEF 157

  Fly   371 ID----------------AEMLVI--------LGQMDAPTKIFEHVYLGSEWNASNLEELQKNGV 411
            ..                .|.|.:        |.....|.:|...:||||.::|:..:.|...|:
Human   158 CSKTKALAAIPPPVPPSATEPLDLGCSSCGTPLHDQGGPVEILPFLYLGSAYHAARRDMLDALGI 222

  Fly   412 RHILNVTREIDNFFPGTFEYFNVRVYDDEKTNLLKYWDDTFRYITRAKAEGSKVLVHCKMGVSRS 476
            ..:|||:.:..|.|.|.::|..:.|.|:.|.::..::.:...||...|....:|||||:.|:|||
Human   223 TALLNVSSDCPNHFEGHYQYKCIPVEDNHKADISSWFMEAIEYIDAVKDCRGRVLVHCQAGISRS 287

  Fly   477 ASVVIAYAMKAYQWEFQQALEHVKKRRSCIKPNKNFLNQL 516
            |::.:||.|...:...::|.|.||:|||.|.||.:|:.||
Human   288 ATICLAYLMMKKRVRLEEAFEFVKQRRSIISPNFSFMGQL 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ssh	NP_733063.1	SSH-N	21..313	CDD:212166	27/136 (20%)
		DEK_C	326..379	CDD:462592	9/76 (12%)
		DSP_slingshot	385..523	CDD:350363	48/132 (36%)
DUSP4	NP_001385.1	DSP_MapKP	9..158	CDD:238723	35/194 (18%)
		DSP_DUSP4	196..336	CDD:350488	48/132 (36%)