Protein Alignment ssh and Dusp8

DIOPT Version :9

• Sequence 1: NP_733063.1
• Gene: ssh / 42986
• FlyBaseID: FBgn0029157
• Length: 1193
• Species: Drosophila melanogaster
• Sequence 2: NP_032774.1
• Gene: Dusp8 / 18218
• MGIID: 106626
• Length: 663
• Species: Mus musculus
• Alignment Length: 686
• Identity: 148/686 - (21%)
• Similarity: 218/686 - (31%)
• Gaps: 273/686 - (39%)

  Fly   386 TKIFEHVYLGSEWNASNLEELQKNGVRHILNVTREIDN-FFPGTFEYFNVRVYDDEKTNLLKYWD 449
            |:|..|:||||:.:..|.:.:.:||:.::||.:..... .|.....:..:.:.|:....||.:.|
Mouse   162 TRILPHLYLGSQKDVLNKDLMTQNGISYVLNASNSCPKPDFICESRFMRIPINDNYCEKLLPWLD 226

  Fly   450 DTFRYITRAKAEGSKVLVHCKMGVSRSASVVIAYAMKAYQWEFQQALEHVKKRRSCIKPNKNFLN 514
            .:..:|.:||....:|:|||..|:||||::.|||.||........|...||.||..|.||.|||.
Mouse   227 KSIEFIDKAKLSSCQVIVHCLAGISRSATIAIAYIMKTMGMSSDDAYRFVKDRRPSISPNFNFLG 291

  Fly   515 QLETYSGMLDAMKNKEKLQRSKSETNLKSTKDARLLPGSE-PTPLIQALNQAKSKSTGEAGVTPD 578
            ||..|.      ::.:.|...:::.....|.:..:.|.:. |.|.:       ..||.|:..|
Mouse   292 QLLEYE------RSLKLLAALQTDGPHLGTPEPLMGPAAGIPLPRL-------PPSTSESAAT-- 341

  Fly   579 GEEEDGSRMHRRSIAQKSQRRMVRRSSSTSPKTQTAVVTKQQSQSMENLTPERSVAEEPKNMRFP 643
            |.|           |..:.|.....:...:|...||..|....|.:..
Mouse   342 GSE-----------AATAAREGSPSAGGDAPIPSTAPATSALQQGLRG----------------- 378

  Fly   644 GSNGENYSVTQNQVLHIQKHTPLSVRTRIHDLEAHRADQLPQQPVWTSLTKLITQTSHLGKSVSG 708
                          ||:..       .|:.|                        |:.|.:|
Mouse   379 --------------LHLSS-------DRLQD------------------------TNRLKRS--- 395

  Fly   709 SSSGNIDSRRDSSCSDVFSSQVDSVFA----------KDEGEKRQRRKTHSWTESLGPSGGIVLD 763
                             ||..:.|.:|          .|.||..:..|..|      ||||.:..
Mouse   396 -----------------FSLDIKSAYAPSRRPDFPGPPDPGEAPKLCKLDS------PSGGTLGL 437

  Fly   764 PTPQQQKQQSNAILRPRGTRQR---ELPSRHASWGSGDNRCCLPQRTSSGSYYDSNRNTTAIFEG 825
            |:|......|....|||..|:|   ..|:|..:.|.|.|            :.|:.|.|..
Mouse   438 PSPSPDSPDSVPECRPRPRRRRPPASSPARSPAHGLGLN------------FGDTARQTPR---- 486

  Fly   826 VIQDLKRSSNCNVIEGVAVAVEP-IVGVGE-----GTVKRTKQKLEESTSLKKRCQEESQELLLE 884
                          .|::....| :.|.|:     |.|
Mouse   487 --------------HGLSALSAPGLPGPGQPAGPGGWV--------------------------- 510

  Fly   885 AVDAGQRRCPSLYRSASSAHSPRQRQPLRCNSEELMHTSDIENKNTTPGDHEATVVLRVQGQTLA 949
                     |.|    .|..:|....|. |.|.|              |......|....|
Mouse   511 ---------PPL----DSPGTPSPDGPW-CFSPE--------------GAQGPGAVFSAFG---- 543

  Fly   950 DDQRIS------GNVQILKQNFEAKAGVVGTGGGGGGGTAAGSGSSSTIATSVSAVAGACSANPG 1008
               |:|      ||        .:.:|..|.|||||||...|.||||:.::|.|
Mouse   544 ---RVSAGAPGPGN--------SSSSGGGGGGGGGGGGGGGGGGSSSSNSSSSS----------- 586

  Fly  1009 KKTTSHQSLPSSPVAQHANHVSAASNSNSSASNSSD 1044
                                 |::|:|:||:|:|||
Mouse   587 ---------------------SSSSSSSSSSSSSSD 601

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ssh	NP_733063.1	SSH-N	21..313	CDD:212166
		DEK_C	328..379	CDD:285919
		DSPc	385..519	CDD:238073	47/133 (35%)
Dusp8	NP_032774.1	DSP_MapKP	10..137	CDD:238723
		DSP_DUSP8	150..300	CDD:350493	48/143 (34%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	313..367		14/73 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	404..624		72/336 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1716
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1576308at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820