Protein Alignment ssh and vhp-1

DIOPT Version :10

• Sequence 1: NP_733063.1
• Gene: ssh / 42986
• FlyBaseID: FBgn0029157
• Length: 1193
• Species: Drosophila melanogaster
• Sequence 2: NP_001343753.1
• Gene: vhp-1 / 173904
• WormBaseID: WBGene00006923
• Length: 661
• Species: Caenorhabditis elegans
• Alignment Length: 673
• Identity: 148/673 - (21%)
• Similarity: 241/673 - (35%)
• Gaps: 150/673 - (22%)

  Fly   213 TTIGLVVPI--LADTTIHLDGDGGFSVKVYEKTHIFKPVSVQAMWSALQTLHKVSKKARENNFYA 275
            :|.||...|  ..|||:.:|..|   ...|.::|:..  |:.|.:|.|     :.::..||....
 Worm    14 STCGLAALIREAPDTTLVVDCRG---FTEYNESHVRH--SMNAFFSKL-----IRRRLFENKLDD 68

  Fly   276 SGPSHDWLSSYERRIESDQSCLNEWNAMDALESRRPPSPDAIRNKPPEKEETESVIKMKLKAIMM 340
            :...|..:           ||.:....||       ...|.:.....:|....       |..:.
 Worm    69 NCLIHQLM-----------SCSSGCTKMD-------EKLDLVLYAEEDKPRGN-------KRRIA 108

  Fly   341 SVDLDEVTSKYIRGRLEEILDMDL--------GEYKSFI--------DAEMLVILGQM------- 382
            |.:..|.|:|.:|...|.:.|.|.        |.:|.|.        .:|.:..|.|.
 Worm   109 SCNAPESTAKIMRVLRERLEDTDKFRSVMVLEGGFKQFAQQYPQLCESSEGMTRLPQSLSQPCLS 173

  Fly   383 ----DAPTKIFEHVYLGSEWNASNLEELQKNGVRHILNVT---------REIDNFFPGTFEYFNV 434
                |..|.|..::||||:.::.:...|....:..::|::         :|..||       ..:
 Worm   174 QPTGDGITLITPNIYLGSQIDSLDETMLDALDISVVINLSMTCPKSVCIKEDKNF-------MRI 231

  Fly   435 RVYDDEKTNLLKYWDDTFRYITRAKAEGSKVLVHCKMGVSRSASVVIAYAMKAYQWEFQQALEHV 499
            .|.|..:..|..|:...:.::.:.:..|.|.|:||..|:|||.::.|:|.|:..:.....|..:|
 Worm   232 PVNDSYQEKLSPYFPMAYEFLEKCRRAGKKCLIHCLAGISRSPTLAISYIMRYMKMGSDDAYRYV 296

  Fly   500 KKRRSCIKPNKNFLNQLETYSGMLDAMKNKEKLQRSKSETNLKSTKDARLLPGSEPTPLIQALNQ 564
            |:||..|.||.||:.||..|..:|......:..|.|:...::.....:.|.|...|
 Worm   297 KERRPSISPNFNFMGQLLEYENVLIKDHVLDYNQASRPHRHMDYYGPSDLCPPKVP--------- 352

  Fly   565 AKSKSTGEAGVTPDGEEEDGSRMHRRSIAQKSQRRMVRRSSSTSPKTQTAVV------TKQQSQS 623
               ||.....|.| |...|.|.....|:::.|.......|||.:..:.||..      |.:|..|
 Worm   353 ---KSASSNCVFP-GSTHDESSPSSPSVSEGSAASEPETSSSAASSSSTASAPPSMPSTSEQGTS 413

  Fly   624 --------MENLTPERSVAEEPKNMRFPGSNGENYS-----------VTQNQVLHIQKHTPLSVR 669
                    ..|:|.:..:...||.:..|...|.:.:           ::.|....|...||:...
 Worm   414 SGTVNVNGKRNMTMDLGLPHRPKALGLPSRIGTSVAELPSPSTELSRLSFNGPEAIAPSTPILNF 478

  Fly   670 TRIHDLEAHRADQLPQQPVWTSLTKLI----TQTSHLGKSVSGSSSGNIDSRRDSSCSDVFSSQV 730
            |       :.....|..||.:|..::|    |..:....|.|...|.:..|...||.|.:...
 Worm   479 T-------NPCFNSPIIPVASSSREVILTLPTPAASSSSSTSSEPSFDFSSFESSSSSSIVVE-- 534

  Fly   731 DSVFAKDEGEKRQRRKTHSWTESLG-PSGGIVLDPTPQQQKQQSNAILRPRG---TRQRELP--- 788
            :..||..|        ..:.:.|:. |||.   ..||......:.:..|.:|   ...::.|
 Worm   535 NPFFASTE--------VPAGSSSISTPSGS---QSTPASASSSAASRCRMKGFFKVFSKKAPAST 588

  Fly   789 SRHASWGSGDNRCCLPQ-RTSSG 810
            |..||...|.:|...|: ..|||
 Worm   589 STPASSTPGTSRAARPECLRSSG 611

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ssh	NP_733063.1	SSH-N	21..313	CDD:212166	22/101 (22%)
		DEK_C	326..379	CDD:462592	13/68 (19%)
		DSP_slingshot	385..523	CDD:350363	40/146 (27%)
vhp-1	NP_001343753.1	DSP_MapKP	12..154	CDD:238723	36/174 (21%)
		DSP_MKP_classIII	180..320	CDD:350416	40/146 (27%)